| Contributor contact details |
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xv | |
| Woodhead Publishing Series in Biomaterials |
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xix | |
| Acknowledgements and dedication |
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xxv | |
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Part I Fundamentals of decontamination in hospitals and healthcare |
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1 | (112) |
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1 The importance of decontamination in hospitals and healthcare |
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3 | (17) |
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3 | (1) |
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1.2 Microbial resistance and infection control |
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4 | (3) |
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1.3 Current water system contamination issues |
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7 | (1) |
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1.4 The impact of prion discovery on sterilisation techniques |
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8 | (6) |
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14 | (1) |
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15 | (5) |
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2 The history of decontamination in hospitals |
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20 | (22) |
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20 | (2) |
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2.2 Healthcare-acquired infection (HAI) |
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22 | (1) |
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2.3 Key figures in decontamination control |
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23 | (3) |
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2.4 Heat for sterilisation and disinfection |
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26 | (8) |
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2.5 Chemical disinfectants |
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34 | (2) |
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2.6 Testing disinfectant activity |
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36 | (1) |
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2.7 European Medical Devices Directives |
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37 | (2) |
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2.8 Incidents of contamination as a result of human error |
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39 | (1) |
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40 | (1) |
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40 | (1) |
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2.11 References and further reading |
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41 | (1) |
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3 The role of standards in decontamination |
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42 | (18) |
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42 | (1) |
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3.2 Relationship of standards to law and guidance |
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43 | (2) |
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3.3 Key aims and principles of standards |
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45 | (1) |
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46 | (1) |
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46 | (1) |
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47 | (1) |
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3.7 International standards |
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48 | (1) |
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3.8 How standards are drafted |
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48 | (3) |
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3.9 How to read and understand a standard |
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51 | (1) |
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3.10 Accessing the most relevant standards and guidance documents |
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52 | (1) |
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3.11 Conclusion and future trends |
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53 | (1) |
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3.12 Sources of further information and advice |
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53 | (1) |
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54 | (1) |
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3.14 Appendix: standards in decontamination |
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54 | (6) |
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4 Infection control in Europe |
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60 | (32) |
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60 | (3) |
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4.2 Data available in Europe |
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63 | (5) |
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4.3 Standards for structures and organizations |
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68 | (1) |
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4.4 Training of personnel |
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69 | (16) |
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4.5 Conclusion and future trends |
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85 | (2) |
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87 | (1) |
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87 | (4) |
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4.8 Appendix: abbreviations |
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91 | (1) |
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5 Future trends in decontamination in hospitals and healthcare |
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92 | (21) |
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92 | (2) |
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5.2 Decontamination in water systems |
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94 | (5) |
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99 | (1) |
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5.4 Control of microorganisms in the built environment |
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100 | (1) |
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101 | (1) |
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5.6 Hand contact sites and environmental cleaning |
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101 | (1) |
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102 | (1) |
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5.8 Automated decontamination systems |
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102 | (1) |
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5.9 Decontamination of prions |
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103 | (3) |
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106 | (7) |
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Part II Decontamination practices in hospitals and healthcare |
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113 | (388) |
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6 Decontamination in primary care: dental and hospital perspectives |
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115 | (27) |
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115 | (1) |
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6.2 Historic background of dental surgery |
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116 | (1) |
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6.3 Potential evidence of infections associated with dentistry |
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117 | (2) |
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6.4 The role of variant Creutzfeldt-Jakob disease (vCJD) in raising standards |
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119 | (2) |
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6.5 Challenges associated with dental instrument decontamination |
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121 | (3) |
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6.6 Instrument decontamination processes for dental surgery |
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124 | (3) |
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6.7 Centralization of dental instrument reprocessing |
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127 | (3) |
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6.8 Quality management systems (QMS) |
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130 | (4) |
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134 | (1) |
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134 | (3) |
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6.11 Sources of further information and advice |
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137 | (1) |
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137 | (5) |
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7 The role of the nurse in decontamination |
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142 | (24) |
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142 | (1) |
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7.2 Regulatory standards and decontamination |
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143 | (1) |
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144 | (1) |
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7.4 Challenges associated with nursing and contamination |
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145 | (5) |
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7.5 Provision of cleaning services |
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150 | (1) |
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7.6 Management of cleaning services |
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151 | (6) |
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7.7 Decontamination of patient equipment |
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157 | (6) |
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163 | (1) |
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7.9 Sources of further information and advice |
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163 | (1) |
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164 | (2) |
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8 Minimising microbial contamination in dental unit water systems and microbial control in dental hospitals |
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166 | (42) |
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8.1 Historical development of the dental chair unit |
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166 | (1) |
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8.2 Dental unit waterlines (DUWLs) |
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167 | (11) |
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8.3 Microorganisms identified in DUWL output water |
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178 | (1) |
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8.4 Evidence to date for infection or disease linked to DUWL biofilm |
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179 | (4) |
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8.5 A microbiological quality standard for DUWL output water |
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183 | (1) |
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8.6 Management of biofilm contamination of DUWLs |
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184 | (9) |
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8.7 Decontamination of DUWLs in dental hospitals |
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193 | (3) |
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8.8 Management of bacterial contamination of washbasin taps and output water in the dental hospital setting |
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196 | (2) |
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8.9 Outlook for the future |
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198 | (1) |
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199 | (9) |
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9 Control of waterborne microorganisms and reducing the threat from Legionella and Pseudomonas |
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208 | (24) |
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208 | (1) |
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208 | (5) |
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9.3 Pseudomonas aeruginosa |
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213 | (4) |
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9.4 The control of Legionella and Pseudomonas in water distribution systems |
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217 | (8) |
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225 | (1) |
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226 | (6) |
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10 The role of continuous microbial debulking in the hospital environment and its effect on reducing hospital-acquired infections (HAI) |
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232 | (22) |
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232 | (2) |
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10.2 Microbes: a clear and present danger common to the built hospital environment |
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234 | (2) |
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10.3 Alterations to the hospital environment and behavior mitigate risk |
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236 | (1) |
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10.4 Risk mitigation: impact of the application of continuously active no-touch solution |
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237 | (8) |
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10.5 Microbial debulking of the environment mitigates hospital-acquired infection (HAI) risk |
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245 | (1) |
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246 | (2) |
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248 | (6) |
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11 Provision and control of water for healthcare purposes |
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254 | (45) |
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254 | (4) |
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11.2 Water quality and water systems in the healthcare environment |
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258 | (3) |
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11.3 Water treatment and water purification technology |
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261 | (9) |
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11.4 Water quality monitoring |
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270 | (1) |
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11.5 Specialist departments and their unique requirements for water quality control |
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270 | (9) |
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11.6 Water Safety Group: an integrated or multi-modal approach |
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279 | (4) |
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11.7 Sustainability and conservation in healthcare water management |
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283 | (1) |
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11.8 Conclusion and future trends' |
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284 | (1) |
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11.9 References and further reading |
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285 | (14) |
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12 Use of gaseous decontamination technologies for wards and isolation rooms in hospitals and healthcare settings |
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299 | (26) |
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299 | (2) |
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12.2 Challenges and considerations for gaseous decontamination in a healthcare setting |
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301 | (8) |
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12.3 Validation methods to determine efficacy |
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309 | (4) |
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12.4 Practical use of gaseous decontamination in hospitals |
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313 | (6) |
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12.5 Conclusion and future trends |
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319 | (1) |
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12.6 Sources of further information and advice |
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320 | (1) |
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320 | (5) |
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13 Biocides and decontamination agents including sporicides for decontamination in hospitals |
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325 | (21) |
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325 | (4) |
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13.2 Currently available biocides and sporicides for use in healthcare and their limitations |
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329 | (5) |
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13.3 Testing standards for actives and sporicides |
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334 | (4) |
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13.4 Incidence of resistance and risk to the hospital patient |
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338 | (2) |
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13.5 Strengths/weaknesses of different disinfectants for a range of microorganisms |
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340 | (1) |
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341 | (1) |
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13.7 Sources of further information and advice |
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342 | (1) |
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342 | (4) |
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14 Decontamination of prions |
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346 | (24) |
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346 | (1) |
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14.2 Prion diseases: transmissible spongiform encephalopathies (TSEs) |
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347 | (1) |
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348 | (1) |
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14.4 Clinical transmission risks |
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349 | (2) |
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14.5 Decontamination investigations |
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351 | (13) |
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364 | (1) |
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365 | (5) |
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15 Cleaning and decontamination of the healthcare environment |
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370 | (28) |
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370 | (1) |
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15.2 Pathogen survival time in the hospital environment |
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371 | (1) |
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15.3 Identifying the main reservoirs of microorganisms |
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372 | (2) |
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15.4 Transmission of contaminants by hands during healthcare |
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374 | (1) |
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15.5 The role of cleaning in reducing the infection risk for patients |
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375 | (6) |
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15.6 Contaminated cleaning equipment and fluids |
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381 | (1) |
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15.7 Assessment of environmental cleanliness |
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382 | (1) |
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15.8 Current and future trends |
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383 | (2) |
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385 | (1) |
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385 | (13) |
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16 The role of protective clothing in healthcare and its decontamination |
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398 | (15) |
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398 | (2) |
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400 | (1) |
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401 | (2) |
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403 | (3) |
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16.5 Cleansing and disposal |
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406 | (4) |
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16.6 Conclusions and future trends |
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410 | (1) |
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410 | (3) |
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17 A guide to no-touch automated room disinfection (NTD) systems |
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413 | (48) |
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413 | (1) |
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17.2 Reasons to consider a no-touch automated room disinfection (NTD) system |
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414 | (1) |
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17.3 What level of surface contamination is a risk for transmission? |
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415 | (3) |
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17.4 Limitations of conventional cleaning and disinfection |
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418 | (2) |
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17.5 Overview of NTD systems |
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420 | (23) |
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17.6 When to consider an NTD system |
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443 | (2) |
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17.7 Using, validating and regulating NTD systems |
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445 | (3) |
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17.8 Sources of further information and advice |
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448 | (1) |
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449 | (1) |
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450 | (11) |
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18 New technologies to control the presence of microorganisms in hospitals |
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461 | (22) |
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461 | (2) |
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18.2 Designing out hospital infection |
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463 | (1) |
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18.3 Modifications to ward layout and design |
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464 | (3) |
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18.4 Modifications to the bed space |
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467 | (4) |
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18.5 Modifications to specific surfaces/patient care items |
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471 | (5) |
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18.6 Conclusion and future trends |
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476 | (1) |
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18.7 Sources of further information and advice |
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477 | (1) |
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477 | (6) |
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19 Testing strategies and international standards for disinfectants |
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483 | (18) |
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483 | (1) |
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19.2 How today's modern efficacy methods differ from those used historically |
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484 | (1) |
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19.3 The use of disinfectants and the role efficacy testing has to play in their selection |
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485 | (1) |
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19.4 The use of international standards in practice |
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486 | (11) |
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497 | (1) |
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498 | (3) |
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Part III Decontamination of surgical instruments and endoscopes |
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501 | (150) |
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20 An overview of current decontamination practices of surgical instruments and medical devices |
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503 | (45) |
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503 | (1) |
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20.2 Purpose of decontamination practice of surgical instruments in central decontamination units (CDUs) |
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504 | (3) |
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20.3 Current regulations, standards and guidance |
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507 | (12) |
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20.4 Risk minimization strategy |
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519 | (2) |
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20.5 Decontamination process |
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521 | (12) |
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20.6 Activities impacting on the decontamination process and the quality of sterile instruments |
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533 | (3) |
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536 | (2) |
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538 | (1) |
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538 | (10) |
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21 An overview of the Choice Framework for local Policy and Procedures (CFPP) for decontamination of surgical instruments |
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548 | (39) |
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548 | (9) |
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21.2 Essential quality requirements (EQR) and best practice (BP) |
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557 | (3) |
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21.3 Application of EQR in surgical instrument and endoscope decontamination |
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560 | (1) |
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21.4 Choice Framework for local Policy and Procedures (CFPP) access |
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561 | (3) |
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21.5 Comparing CFPP with the established Health Technical Memorandum (HTM) model |
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564 | (14) |
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21.6 Conclusions and future trends |
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578 | (3) |
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21.7 Sources of further information and advice |
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581 | (1) |
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582 | (1) |
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21.9 References and further reading |
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582 | (5) |
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22 An overview of new technologies for the decontamination of surgical instruments and the quantification of protein residues: low-pressure radiofrequency (RF) gas-plasma decontamination and epifluorescence scanning (EFSCAN) detection |
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587 | (11) |
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587 | (2) |
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22.2 Radiofrequency (RF) gas-plasma removal of prion infectivity |
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589 | (1) |
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22.3 Potential future processes for prion removal |
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590 | (1) |
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22.4 RF gas-plasma inactivation of bacterial contamination |
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590 | (1) |
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22.5 An example of instrument decontamination using low-pressure gas-plasma |
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591 | (1) |
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22.6 Monitoring decontamination |
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591 | (1) |
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22.7 Epifluorescence scanning (EFSCAN) |
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592 | (2) |
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22.8 EFSCAN contamination monitoring for RF gas-plasma treated instruments |
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594 | (1) |
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594 | (1) |
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595 | (1) |
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595 | (3) |
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23 Efficacy of current and novel cleaning technologies (ProReveal) for assessing protein contamination on surgical instruments |
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598 | (22) |
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598 | (3) |
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23.2 General principles of protein detection |
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601 | (2) |
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23.3 Current general methods of protein detection (ninhydrin, Biuret, dyes): sensitivity, specificity and validation |
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603 | (4) |
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23.4 Methods of protein detection based on fluorescence |
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607 | (7) |
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23.5 Other possible technologies |
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614 | (1) |
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23.6 Strengths and weaknesses of new technologies |
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615 | (2) |
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617 | (1) |
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618 | (2) |
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24 Decontamination of flexible endoscopes |
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620 | (19) |
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620 | (2) |
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622 | (3) |
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24.3 Flexible endoscope decontamination |
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625 | (1) |
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24.4 Decontamination process |
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626 | (2) |
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24.5 Assessing and selecting endoscope washer-disinfector (EWD) systems |
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628 | (1) |
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24.6 Water treatment and potential machine contamination issues |
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629 | (1) |
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24.7 Endoscopy accessories |
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629 | (1) |
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24.8 Tracking and traceability |
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630 | (1) |
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24.9 Recontamination risks and preventative storage of endoscopes |
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631 | (2) |
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24.10 Testing for rinse water contamination |
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633 | (1) |
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24.11 Decontamination facilities |
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634 | (3) |
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24.12 Reasons for decontamination failure |
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637 | (1) |
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638 | (1) |
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638 | (1) |
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25 Sterilisation of flexible endoscopes |
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639 | (12) |
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25.1 Introduction: key principles of sterilising flexible endoscopes |
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639 | (1) |
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25.2 Why sterilise flexible endoscopes? |
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640 | (2) |
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25.3 Problems associated with sterilisation of flexible endoscopes |
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642 | (1) |
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25.4 Methods used in the sterilisation of endoscopes |
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642 | (4) |
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25.5 Testing effectiveness and application of standards |
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646 | (1) |
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25.6 Example of an `in use' application |
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647 | (1) |
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648 | (1) |
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25.8 Sources of further information and advice |
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648 | (1) |
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649 | (2) |
| Index |
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651 | |