Satoh presents this text on developmental genomics of the simple chordates and promising model organisms the ascidians. After an introduction to the class and an overview of larval and juvenile development, a pair of chapters address genomics, transcriptomics, proteomics, research tools and paradigms. The main content begins with a discussion of the role of maternal transcripts and then covers development of specific body parts and systems including the larval tail muscle, endoderm, epidermis, notochord, nervous systems, mesenchyme, regulatory control of the body plan, heart, germline, metamorphosis, immune and hematological systems. The last two chapters discuss colonial behavior, asexual reproduction, and the link between embryology and evolutionary research. Annotation ©2014 Ringgold, Inc., Portland, OR (protoview.com)
The simplicity and lack of redundancy in their regulatory genes have made ascidians one of the most useful species in studying developmental genomics. In Developmental Genomics of Ascidians, Dr. Noriyuki Satoh explains the developmental genomics of ascidians, stresses the simplicity of Ciona developmental system, and emphasizes single-cell level analyses. This book actively accentuates the advantages of using ascidians as model organisms in an up-and-coming field of developmental genomics.