This expert volume in the
Diagnostic Pathology series is an
excellent resource for practitioners at all levels of experience and training. Covering all aspects of hospital autopsy in the way it is practiced clinically, this volume incorporates the most up-to-date scientific and technical knowledge to provide a
comprehensive overview of all key issues relevant to today’s practice, helping pathologists accurately determine the cause and mechanism of in-hospital death. Richly illustrated and easy to use,
Diagnostic Pathology: Hospital Autopsy, second edition, is
a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.
- Features complete coverage of every aspect of autopsy practice?including clinical presentation with chart review, technical and diagnostic aspects of autopsy performance, and reporting
- Presents classic autopsy techniques while also emphasizing the role of molecular studies and other laboratory and ancillary tests not commonly thought of during autopsy practice
- Contains new chapters on emerging pathogens and medical entities (deaths from COVID-19 or vaccine complications, multisystem inflammatory disorders in children, adenoviral hepatitis in children, and more), toxicity/pathology associated with new drug therapies (CAR-T, mRNA vaccine-related immune events, etc.), and new cardiac and other medical devices
- Features new or updated content on morgue/autopsy suite maintenance, enhanced biosafety techniques, the role of the autopsy practitioner in a pandemic setting, and more
- Provides important clinical and diagnostic information through more than 1,100 clinical and gross pathology photographs, histologic images, full-color illustrations, and radiologic images
- Includes case presentations highlighting important aspects of reporting that impact clinicians as well as next of kin
- Focuses on pathologists in hospital settings, but also provides value to forensic pathologists, private practice pathologists, and others involved in death investigation, such as coroners, medical examiners, law enforcement, and pathology residents
- Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference
- Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.
Arvustused
"...an updated overview of the pathology of hospital autopsy, [ and] a useful reference for any pathologist performing a hospital autopsy, forensic pathologists, pathology residents, and autopsy technicians.... includes many case presentations that put the information into a more personal and decedent-centered context, which often makes the information easier to retain. This book provides an excellent foundation for training pathologists and a good review for practicing pathologists with respect to the subject of hospital autopsy. It is well-organized, detailed, and contains many color gross photographs, photomicrographs, and diagrams to help integrate key points from the text.... a good reference book for experienced pathologists and will serve as a useful introduction text with respect to hospital autopsy for anyone studying this subject." ©Doody's Book Review Service, 2025, Elizabeth S Higginson, MD, PhD (University of Michigan Medical School)
SECTION 1: AUTOPSY FUNDAMENTALS
INTRODUCTION
4 History of Autopsy
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
8 Autopsy Safety
Billie S. Fyfe, MD
AUTOPSY PERFORMANCE
EXTERNAL EXAMINATION
10 Medical Intervention
Brandon T. Larsen, MD, PhD
14 Postmortem Changes and External Examination
Billie S. Fyfe, MD
INTERNAL EXAMINATION
18 Body Cavities
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD,
FRCPA
22 Cardiovascular System
Dylan V. Miller, MD
26 Respiratory System
Leslie A. Litzky, MD
30 Hematopoietic System
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
36 Gastrointestinal System
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
44 Hepatobiliary System
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
50 Genitourinary System
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
56 Endocrine System
Billie S. Fyfe, MD
62 Central Nervous System
Hasini Reddy, MD, DPhil
68 Peripheral Nervous System
Roy H. Rhodes, MD, PhD
72 Integumentary System
Dylan V. Miller, MD
76 Oral Cavity
Billie S. Fyfe, MD
80 Medical Devices
Brandon T. Larsen, MD, PhD
LABORATORY TESTING
84 Chemistry
Rachel Hudacko, MD
86 Microbiology
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
90 Cytology
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
POSTMORTEM IMAGING
96 Postmortem Radiography and Virtual Autopsy
Billie S. Fyfe, MD
POSTMORTEM HISTOLOGY
102 Postmortem Histology
Billie S. Fyfe, MD
AUTOPSY CONSENT AND REPORTING
AUTOPSY CONSENT
106 Consent Process and Legal Considerations
Dylan V. Miller, MD
AUTOPSY REPORTING
110 Death Certificate
Billie S. Fyfe, MD and Alex Williamson, MD
114 Autopsy Report
Corinne L. Fligner, MD and Dylan V. Miller, MD
118 Presenting Autopsy Findings
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
SECTION 2: ORGAN SYSTEM APPROACH TO AUTOPSY
SUDDEN AND UNEXPECTED DEATH
CARDIOVASCULAR
122 Pulmonary Thromboembolism
Billie S. Fyfe, MD
124 Acute Myocardial Infarction
Vidhya Nair, MD and Dylan V. Miller, MD
128 Cardiomyopathy
Dylan V. Miller, MD
132 Myocarditis
Monica P. Revelo, MD, PhD and Dylan V. Miller, MD
138 Cardiac Conduction System
Dylan V. Miller, MD
144 Aortic Dissection
Billie S. Fyfe, MD
150 Abdominal Aortic Aneurysm
Billie S. Fyfe, MD
RESPIRATORY
152 Pulmonary Edema
Leslie A. Litzky, MD
156 Pulmonary Hemorrhage
Leslie A. Litzky, MD
160 Tension Pneumothorax
Leslie A. Litzky, MD
GASTROINTESTINAL
164 Upper Gastrointestinal Hemorrhage
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD,
FRCPA
168 Lower Gastrointestinal Hemorrhage
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
172 Intestinal Ischemia
Rachel Hudacko, MD
HEPATOBILIARY
176 Hepatic Hemorrhage
Rachel Hudacko, MD
180 Hemorrhagic Pancreatitis
Rachel Hudacko, MD
184 Acute Liver Failure
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
GENITOURINARY
188 Pregnancy Complications
Corinne L. Fligner, MD
194 Acute Renal Failure
Monica P. Revelo, MD, PhD and Paisit Paueksakon, MD
ENDOCRINE
204 Adrenal Insufficiency
Dylan V. Miller, MD
208 Adrenocortical Excess
Patrick Lento, MD
CNS
212 Seizure Disorders
Hasini Reddy, MD, DPhil
216 Subdural Hemorrhage
Roy H. Rhodes, MD, PhD
220 Subarachnoid Hemorrhage
Roy H. Rhodes, MD, PhD
224 Stroke
Hasini Reddy, MD, DPhil
POSTOPERATIVE/POST-INTERVENTIONAL DEATH
IATROGENIC
230 Therapeutic Complications
Billie S. Fyfe, MD
CARDIOVASCULAR
234 Coronary Artery Bypass Grafting
Dylan V. Miller, MD
238 Coronary Artery Stenting
Dylan V. Miller, MD
242 Valve Replacement (Including Transcatheter)
Brandon T. Larsen, MD, PhD
248 Ventricular Assist Devices
Brandon T. Larsen, MD, PhD
252 Thoracic Aortic Aneurysm Repair
Billie S. Fyfe, MD and George P. Batsides, MD
GASTROINTESTINAL AND HEPATOBILIARY
258 Pancreas Resection
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
262 Gastrectomy and Esophagectomy
Rachel Hudacko, MD
266 Bariatric Surgery
Rachel Hudacko, MD
CNS
270 Central Nervous System Tumors
Roy H. Rhodes, MD, PhD
276 Cerebral Aneurysm and Vascular Malformation
Roy H. Rhodes, MD, PhD
SECTION 3: DISEASE PROCESS APPROACH TO AUTOPSY
TRANSPLANTATION
284 Heart Transplant
Dylan V. Miller, MD
290 Lung Transplant
Leslie A. Litzky, MD
294 Kidney Transplant
Monica P. Revelo, MD, PhD and Paisit Paueksakon, MD
304 Liver Transplant
Rachel Hudacko, MD and Patrick Lento, MD
310 Pancreas Transplant
Monica P. Revelo, MD, PhD
314 Bone Marrow Transplant
Dylan V. Miller, MD
318 Deceased Donor Autopsy
Billie S. Fyfe, MD
INFECTION-RELATED DEATH
SYSTEMIC INFECTION/SEPSIS OVERVIEW
320 HIV/AIDS
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
324 Shock and Sepsis
Billie S. Fyfe, MD and Christine Minerowicz, MD
ORGAN SYSTEM INFECTION
330 Bronchopneumonia
Leslie A. Litzky, MD
334 Infective Endocarditis
Dylan V. Miller, MD
338 Clostridium difficile Enterocolitis
Billie S. Fyfe, MD
342 Viral Hepatitis
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
346 Urosepsis
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
NEOPLASIA-ASSOCIATED DEATH
350 Neoplasia-Associated Death
Billie S. Fyfe, MD
356 Death Due to Paraneoplastic Effect
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
OTHER COMMON HOSPITAL DEATH
360 Chronic Obstructive Pulmonary Disease
Harold Sanchez, MD, FCAP and Rebecca A. Irvine, MD, FRCPA
364 Ventilator Dependent Respiratory Failure
Leslie A. Litzky, MD
368 Chronic Liver Failure
Rachel Hudacko, MD and Jeanine Chiaffarano, DO
374 Chronic Renal Failure
Monica P. Revelo, MD, PhD
382 Dementia and Neurodegenerative Disease
Hasini Reddy, MD, DPhil
AUTOIMMUNE DISEASE-RELATED DEATH
386 Amyloidosis
Billie S. Fyfe, MD
390 SLE/MCTD
David Priemer, MD
394 Dermatomyositis
David Priemer, MD
398 Arteritis
Billie S. Fyfe, MD
Dylan V. Miller, MD, is a clinical professor with the Department of Pathology at the University of Utah School of Medicine. Dr. Miller is also Director of Electron Microscopy and Immunostains at
Intermountain Central Laboratory in
Salt Lake City, Utah
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