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xiii | |
Introduction |
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xv | |
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1 Maximizing the Value of Engineering and Technology Research in Healthcare: Development-Focused Health Technology Assessment |
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1 | (28) |
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1 | (2) |
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3 | (1) |
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1.3 What Is Development-Focused HTA? |
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4 | (1) |
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1.4 Illustration of Features of Development-Focused HTA |
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5 | (2) |
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6 | (1) |
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1.4.2 Development-Focused HTA |
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6 | (1) |
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1.5 Activities of Development-Focused HTA |
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7 | (2) |
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1.6 Analytical Methods of Development-Focused HTA |
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9 | (6) |
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1.6.1 Clinical Value Assessment |
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11 | (1) |
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1.6.2 Economic Value Assessment |
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11 | (3) |
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1.6.3 Evidence Generation |
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14 | (1) |
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1.7 What Are the Challenges in the Development and Assessment of Medical Devices? |
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15 | (5) |
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1.7.1 What Are Medical Devices? |
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15 | (1) |
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1.7.2 Challenges Common to All medical Devices |
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16 | (1) |
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1.7.2.1 Licensing and Regulation |
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16 | (1) |
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17 | (1) |
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18 | (1) |
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1.7.3 Challenges Specific to Some Categories of Device |
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19 | (1) |
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19 | (1) |
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1.7.3.2 Short Lifespan and Incremental Improvement |
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19 | (1) |
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19 | (1) |
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1.7.3.4 Indirect Health Benefit |
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19 | (1) |
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1.7.3.5 Behavioral and Other Contextual Factors |
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20 | (1) |
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1.7.3.6 Budgetary Challenges |
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20 | (1) |
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1.8 The Contribution of DF-HTA in the Development and Translation of Medical Devices |
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20 | (2) |
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1.8.1 Case Study 1 -- Identifying and Confirming Needs |
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21 | (1) |
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1.8.2 Case Study 2 -- What Difference Could This Device Make? |
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21 | (1) |
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1.8.3 Case Study 3 -- Which Research Project Has the Most Potential? |
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21 | (1) |
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1.8.4 Case Study 4 -- What Is the Required Performance to Deliver Clinical Utility? |
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21 | (1) |
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1.8.5 Case Study 5 -- What Are the Key Parameters for Evidence Generation? |
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22 | (1) |
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22 | (7) |
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23 | (6) |
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2 Contactless Radar Sensing for Health Monitoring |
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29 | (32) |
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2.1 Introduction: Healthcare Provision and Radar Technology |
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29 | (3) |
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2.2 Radar and Radar Data Fundamentals |
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32 | (10) |
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2.2.1 Principles of Radar Systems |
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32 | (3) |
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2.2.2 Principles of Radar Signal Processing for Health Applications |
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35 | (3) |
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2.2.3 Principles of Machine Learning Applied to Radar Data |
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38 | (3) |
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2.2.4 Complementary Approaches: Passive Radar and Channel State Information Sensing |
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41 | (1) |
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2.3 Radar Technology in Use for Health Care |
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42 | (8) |
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2.3.1 Activities Recognition and Fall Detection |
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42 | (4) |
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46 | (2) |
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2.3.3 Vital Signs and Sleep Monitoring |
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48 | (2) |
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2.4 Conclusion and Outstanding Challenges |
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50 | (2) |
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52 | (9) |
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2.5.1 Paradigm Change in Radar Sensing |
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52 | (3) |
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55 | (1) |
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55 | (6) |
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3 Pervasive Sensing: Macro to Nanoscale |
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61 | (20) |
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61 | (3) |
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3.2 The Anatomy of a Human Skin |
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64 | (1) |
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3.3 Characterization of Human Tissue |
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65 | (5) |
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3.4 Tissue Sample Preparation |
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70 | (1) |
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3.5 Measurement Apparatus |
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70 | (2) |
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3.6 Simulating the Human Skin |
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72 | (4) |
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3.6.1 Human Body Channel Modelling |
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73 | (3) |
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3.7 Networking and Communication Mechanisms for Body-Centric Wireless Nano-Networks |
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76 | (2) |
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78 | (3) |
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78 | (3) |
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4 Biointegrated Implantable Brain Devices |
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81 | (14) |
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81 | (2) |
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4.2 Neural Device Interfaces |
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83 | (1) |
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4.3 Implant Tissue Biointegration |
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84 | (3) |
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4.4 MRI Compatibility of the Neural Devices |
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87 | (3) |
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90 | (5) |
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90 | (5) |
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5 Machine Learning for Decision Making in Healthcare |
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95 | (22) |
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95 | (3) |
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98 | (1) |
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99 | (6) |
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5.3.1 Collection of the Data |
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99 | (1) |
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5.3.2 Selection of the Window Size |
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100 | (1) |
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5.3.3 Extraction of the Features |
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101 | (1) |
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5.3.4 Selection of the Features |
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101 | (1) |
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5.3.5 Deployment of the Machine Learning Models |
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102 | (1) |
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5.3.6 Quantitative Assessment of the Models |
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103 | (1) |
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5.3.7 Parallel Processing |
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104 | (1) |
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105 | (3) |
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5.5 Analysis and Discussion |
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108 | (5) |
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108 | (1) |
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109 | (1) |
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5.5.3 Feature Combinations |
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109 | (2) |
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5.5.4 Machine Learning Algorithms |
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111 | (2) |
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113 | (4) |
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113 | (4) |
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6 Information Retrieval from Electronic Health Records |
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117 | (12) |
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117 | (1) |
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118 | (4) |
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6.2.1 Parallel LSI (PLSI) |
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119 | (2) |
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6.2.2 Distributed LSI (DLSI) |
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121 | (1) |
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122 | (4) |
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126 | (3) |
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126 | (3) |
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7 Energy Harvesting for Wearable and Portable Devices |
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129 | (24) |
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129 | (1) |
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7.2 Energy Harvesting Techniques |
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130 | (15) |
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130 | (4) |
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7.2.2 Piezoelectric Energy Harvesting |
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134 | (3) |
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7.2.3 Thermal Energy Harvesting |
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137 | (2) |
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139 | (2) |
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7.2.4 RF Energy Harvesting |
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141 | (4) |
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145 | (8) |
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146 | (7) |
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8 Wireless Control for Life-Critical Actions |
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153 | (16) |
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153 | (2) |
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8.2 Wireless Control for Healthcare |
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155 | (1) |
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8.3 Technical Requirements |
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156 | (1) |
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156 | (1) |
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156 | (1) |
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8.3.3 Security and Privacy |
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157 | (1) |
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8.3.4 Edge Artificial Intelligence |
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157 | (1) |
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157 | (2) |
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158 | (1) |
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159 | (1) |
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8.5 Co-Design System Model |
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159 | (6) |
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159 | (2) |
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8.5.2 Performance Evaluation Criterion |
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161 | (1) |
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8.5.2.1 Control Performance |
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161 | (1) |
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8.5.2.2 Communication Performance |
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161 | (1) |
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8.5.3 Effects of Different QoS |
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162 | (1) |
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163 | (2) |
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165 | (4) |
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165 | (4) |
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9 Role of D2D Communications in Mobile Health Applications: Security Threats and Requirements |
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169 | (18) |
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169 | (1) |
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9.2 D2D Scenarios for Mobile Health Applications |
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170 | (1) |
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9.3 D2D Security Requirements and Standardization |
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171 | (5) |
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9.3.1 Security Issues on Configuration |
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171 | (1) |
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9.3.1.1 Configuration oftheProSe Enabled UE |
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171 | (1) |
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9.3.2 Security Issues on Device Discovery |
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172 | (1) |
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9.3.2.1 Direct Request and Response Discovery |
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172 | (1) |
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9.3.2.2 Open Direct Discovery |
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173 | (1) |
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9.3.2.3 Restricted Direct Discovery |
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173 | (1) |
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9.3.2.4 Registration in Network-Based ProSe Discovery |
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173 | (1) |
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9.3.3 Security Issues on One-to-Many Communications |
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174 | (1) |
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9.3.3.1 One-to-many communications between UEs |
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174 | (1) |
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9.3.3.2 Key Distribution for Group Communications |
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174 | (1) |
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9.3.4 Security Issues on One-to-One Communication |
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175 | (1) |
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9.3.4.1 One-to-One ProSe Direct Communication |
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175 | (1) |
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9.3.4.2 One-to-One ProSe Direct Communication |
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175 | (1) |
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9.3.5 Security Issues on ProSe Relays |
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175 | (1) |
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9.3.5.1 Maintaining 3GPP Communication Security through Relay |
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175 | (1) |
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176 | (1) |
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176 | (1) |
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176 | (7) |
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176 | (2) |
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178 | (1) |
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9.4.3 Social Trust and Social Ties |
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178 | (2) |
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180 | (1) |
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9.4.5 Physical Layer Security |
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180 | (3) |
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183 | (1) |
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183 | (4) |
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183 | (4) |
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10 Automated Diagnosis of Skin Cancer for Healthcare: Highlights and Procedures |
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187 | (26) |
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187 | (1) |
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10.2 Framework of Computer-Aided Skin Cancer Classification Systems |
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188 | (17) |
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188 | (1) |
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10.2.2 Image Pre-Processing |
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189 | (1) |
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10.2.2.1 Color Contrast Enhancement |
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189 | (1) |
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10.2.2.2 Artifact Removal |
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190 | (1) |
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10.2.3 Image Segmentation |
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191 | (1) |
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10.2.3.1 Thresholding-Based Segmentation |
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192 | (1) |
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10.2.3.2 Edge-Based Segmentation |
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192 | (1) |
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10.2.3.3 Region-Based Segmentation |
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193 | (1) |
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10.2.3.4 Active Contours-Based Segmentation |
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193 | (1) |
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10.2.3.5 Artificial Intelligence-Based Segmentation |
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194 | (1) |
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10.2.4 Feature Extraction |
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195 | (1) |
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10.2.4.1 Color-based Features |
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196 | (1) |
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10.2.4.2 Dimensional Features |
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196 | (1) |
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10.2.4.3 Texture-Based Features |
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196 | (1) |
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10.2.4.4 Dermoscopic Rules and Methods |
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197 | (3) |
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200 | (1) |
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201 | (1) |
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10.2.7 Classification Performance Evaluation |
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202 | (1) |
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10.2.8 Computer-Aided Diagnosis Systems in Dermoscopic Images |
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203 | (2) |
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205 | (8) |
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205 | (1) |
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205 | (8) |
Conclusions |
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213 | (2) |
Index |
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215 | |