E-raamat: Environmental Stressors in Health and Disease

Series Introduction iii Lester Packer Enrique Cadenas Preface vii Contributors xiii I. Molecular and Cellular Aspects of Prooxidant Environmental Xenobiotics Free Radical Reactions in Human Disease 1(16) Barry Halliwell Radicals and Inflammation: Mediators and Modulators 17(36) Claire A. Davies David R. Blake Paul G. Winyard Autoimmunity Caused by Oxidizing Foreign Compounds 53(28) Kaye H. Kilburn Role of Oxidative Stress in Chemical Carcinogenesis 81(22) James E. Klaunig Lisa M. Kamendulis Proposed Mechanisms of Arsenic Toxicity Carcinogenesis 103(12) Michael I. Luster Petia P. Simeonova Redox Regulation of Gene Expression and Transcription Factors in Response to Environmental Oxidants 115(20) Hiroshi Masutani Akira Nishiyama Yong-Won Kwon Yong-Chul Kim Hajime Nakamura Junji Yodoi II. Target Organs of Environmental Oxidants: Lung Cigarette Smoking and Pulmonary Oxidative Damage 135(22) Ching K. Chow Health Effects of Diesel Exhaust and Diesel Exhaust Particles 157(28) Masaru Sagai Takamichi Ichinose The Role of Free Radicals in Asbestos- and Silica-Induced Fibrotic Lung Diseases 185(18) Arti Shukla Cynthia R. Timblin Brooke T. Mossman Andrea Hubbard Reactive Oxygen Species and Silica-Induced Carcinogenesis 203(22) Xianglin Shi Min Ding Fei Chen Val Vallyathan Vince Castranova Atmospheric Oxidants and Respiratory Tract Surfaces 225(12) Carroll E. Cross Samuel Louie Sunye Kwack Pat Wong Sharanya Reddy Albert van der Vliet III. Target Organs of Environmental Oxidants: Skin Redox Modulation and Oxidative Stress in Dermatotoxicology 237(34) Jurgen Fuchs Maurizio Podda Thomas Zollner Dermatotoxicology of Environmental and Occupational Chemical Hazards: Agents and Action 271(48) Jurgen Fuchs Photooxidative Stress in Skin and Regulation of Gene Expression 319(16) Lee Ann Laurent-Applegate Stefan Schwarzkopf Ozone Stress in the Skin Barrier 335(10) Stefan U. Weber Lester Packer Immunotoxicity of Environmental Agents in the Skin 345(20) Santosh K. Katiyar Hasan Mukhtar IV. Target Organs of Environmental Oxidants: Eye Environmental Stressors and the Eye 365(16) John R. Trevithick Kenneth P. Mitton Free Radicals and Aging of Anterior Segment Tissues of the Eye 381(42) Keith Green The Role of Ocular Free Radicals in Age-Related Macular Degeneration 423(34) Paul S. Bernstein Nikita B. Katz Nutritional Influences on Risk for Cataract 457(32) Allen Taylor Index 489

Jurgen Fuchs is Research Associate and clinical faculty member, Department of Dermatology, Johann Wolfgang Goethe University, Frankfurt, Germany. The author of approximately 200 published articles and the coeditor of Lipoic Acid in Health and Disease, Oxidative Stress in Dermatology, Vitamin C in Health and Disease, and Vitamin E in Health and Disease (all titles, Marcel Dekker, Inc.), he received the Ph.D. degree (1985) in biology and the M.D. degree (1986) from the University of Frankfurt, Germany. Lester Packer is an Adjunct Professor of Molecular Pharmacology and Toxicology at the University of Southern California School of Pharmacy, Los Angeles. The recipient of the Optolind Skin Research Prize 2000, he is the author, coauthor, editor, or coeditor of over 700 journal articles, book chapters, and books, including Antioxidants in Diabetes Management, Biothiols in Health and Disease, Flavonoids in Health and Disease, Free Radicals in Brain Pathophysiology, the Handbook of Antioxidants, the Handbook of Synthetic Antioxidants, Lipoic Acid in Health and Disease, Nutraceuticals in Health and Disease Prevention, Oxidative Stress in Dermatology, Redox Regulation in Cell Signaling and Its Clinical Application, Retinoids, Understanding the Process of Aging, Vitamin C in Health and Disease, and Vitamin E in Health and Disease (all titles, Marcel Dekker, Inc.). Dr. Packer received the B.S. (1951) and M.S. (1952) degrees in biology and chemistry from Brooklyn College, New York, and the Ph.D. degree (1956) in microbiology and biochemistry from Yale University, New Haven, Connecticut.