The book is a compact yet comprehensive practical resource that highlights all must-know information on non-alcoholic fatty liver disease (NAFLD).
Covering the major issues dominating the field, this book offers a broad vision on NAFLD using key data for a deep and thorough understanding of the latest diagnostic methods, treatment options, potential complications, and disease management strategies to improve patient outcomes.
The volume bridges the trans-disciplinary divide between hepatologists, cardiologists, nephrologists, psychiatrists, oncologists and dermatologists in order to cover the complex management of NAFLD in a single volume.
It operates under a modern definition of NAFLD that acknowledges the range of presentations related to extrahepatic complications that hepatologists see in daily practice, while also delving into unanswered questions and future directions regarding treatment options.
Offering practical, clinical guidance in addition to capturing the new promising therapeutic approaches in the pipeline, this book is an essential reference for clinicians, researchers and students.
Chapter 1: The nomenclature and definition of nonalcoholic fatty liver
disease.
Chapter 2: Nonalcoholic fatty liver disease versus metabolic
associated fatty liver disease.
Chapter 3: Natural history of nonalcoholic
fatty liver disease.
Chapter 4: Hepatocellular carcinoma in nonalcoholic
fatty liver disease.
Chapter 5: Genetics and epigenetics in nonalcoholic
fatty liver disease.
Chapter 6: The place of transabdominal liver biopsy in
nonalcoholic fatty liver disease.
Chapter 7: Alternative methods for liver
biopsy - endoscopic ultrasound-guided and transjugular liver biopsy
endoscopic ultrasound-guided and transjugular liver biopsy.
Chapter 8:
Morphopathology of nonalcoholic fatty liver disease.
Chapter 9: 2D shear
wave elastography performance in the diagnosis of nonalcoholic fatty liver
disease.
Chapter 10: Vibration controlled transient elastography and
controlled attenuation parameter for staging nonalcoholic fatty liver
disease.
Chapter 11: The value ofserologic markers/scores in the assessment
of nonalcoholic fatty liver disease.
Chapter 12: Nonalcoholic fatty liver
disease within other causes of chronic liver diseases.-Chapter 13:
Pathophisiology and risk stratification in cardiovascular diseases and
NAFLD.
Chapter 14: Type 2 diabetes mellitus and insulin resistance in
nonalcoholic fatty liver disease.
Chapter 15: Nonalcoholic Fatty Liver
Disease and Chronic Kidney Disease.
Chapter 16: Endocrinopathies in
nonalcoholic fatty liver disease.
Chapter 17: Nonalcoholic Fatty liver
disease and extraheoatic malignancies.
Chapter 18: Psychological burden of
NAFLD and psychiatric disorders as extrahepatic manifestations.
Chapter 19:
Obstructive sleep apnea syndrome and nonalcoholic fatty liver disease.-
Chapter 20: Nonalcoholic fatty liver disease and psoriasis.
Chapter 21:
Current management and pipeline treatment approaches in NAFLD summary of
ongoing RCTs and future directions.
Chapter 22: Practical clinical cases in
nonalcoholic fatty liver disease.
Anca Trifan, MD, PhD, FEBGH, FRCP (London) is a Professor of Gastroenterology and Internal Medicine, and Director of the Department of Internal Medicine of the Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, Head of the Institute of Gastroenterology and Hepatology, Iasi, Romania. Her research interests include viral hepatitis, liver cirrhosis, liver transplant, acute-on chronic liver failure, non-invasive assessment of liver fibrosis, inflammatory bowel disease, biliary tract disorders, and Clostridium difficile infection. She has published numerous original papers, books and chapters of books and has been actively involved in the peer-review process of many high impact factor journals. She has been involved in the medical teaching from the beginning of her career. She received many prizes form scientific organization (e.g., Rising Stars in Gastroenterology awarded by UEG). She is past president of The Romanian Society of Gastroenterology and Hepatology,member of The Academy of Medical Sciences, member of the European Board of Gastroenterology, AGA fellow and member of The American Association for the Study of Liver Diseases.
Carol Stanciu, MD, PhD, FRCP (London) is a Professor of Gastroenterology and Internal Medicine, University of Medicine and Pharmacy Gr. T. Popa, Iasi, a Fellow of the Academy of Medical Sciences, and a Fellow of Romanian Academy. Dr. Carol Stanciu is one of the main founders of gastroenterology, diagnostic and therapeutic endoscopy in Romania. He graduated from the Faculty of Medicine, University of Medicine and Pharmacy Gr.T.Popa Iasi where he also received PhD and DSc. He is a former President of Romanian Society of Endoscopy (1996-2000), President of Romanian Society of Gastroenterology and Hepatology (2000-2008), Chairman Ethics Committee World Organization of Gastroenterology (1994-2002). He has always been involved in all areas of academic life: medical training, especiallytherapeutic endoscopy, patient care, administrative work (President of the University of Medicine and Pharmacy Gr. T. Popa between 1992-2004, and Dean between 2004-2008) and mentorship. His research interests include gastrointestinal motility, viral hepatitis, liver cirrhosis, liver transplant, acute-on chronic liver failure, non-invasive assessment of liver fibrosis, inflammatory bowel disease, biliary tract disorders, and Clostridium difficile infection. He has published numerous original papers, books and book chapters and has been actively involved in the peer-review process of prestigious high impact factor journals. He received many awards from Romanian Presidency, French Presidency, WGO, Romanian Society of Gastroenterology and Hepatology and many universities.
Cristina Muzica, MD, PhD, is an Assistant Professor of Gastroenterology and Internal Medicine, University of Medicine and Pharmacy Gr. T. Popa, Iasi. Her primary research interests are in thefield of hepatology and consist of hepatocellular carcinoma, viral hepatitis, non-alcoholic fatty liver disease and alcoholic liver diseases. During her career she published several papers including book chapters about the aforementioned themes. She is a member of the Romanian Society of Gastroenterology, United European Gastroenterology, European Association for the Study of the Liver, and Romanian Society of Neurogastroenterology.
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