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E-raamat: Evidence-based Clinical Chinese Medicine - Volume 14: Unipolar Depression

Editor-in-chief (Guangdong Provincial Hospital Of Chinese Medicine, China), (Rmit Univ, Australia), Editor-in-chief (Rmit Univ, Australia), (Guangdong Provincial Hospital Of Chinese Medicine, China)
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"This book is the fourteenth volume in the Evidence-based Clinical Chinese Medicine series and is essential for Chinese medicine practitioners interested in treating unipolar depression using Chinese medicine. It uses a 'whole evidence' approach and provides an in-depth analysis of Chinese medicine treatments for depression, including a summary of Chinese medicine treatments used in classical Chinese medicine literature, as well as treatments that have been tested in clinical trials. High-quality and rigorous scientific methodology is used to evaluate the clinical trial literature of Chinese medicine treatments for unipolar depression, treatment modalities including Chinese herbal medicine, acupuncture and other Chinese medicine therapies. The findings are analyzed and potential implications for clinical practice and research are explored. Chinese medicine practitioners and students who want to keep up to date with the latest research to support and incorporate into their clinical practice, this book is ideal. The different modalities of treatment for unipolar depression covered in this book includes herbal medicine, acupuncture and combination of these therapies. Treatment effects for depression are described in change in depression severity, change in quality of life and relapse rate. Further, herbal formulae, herb ingredients and acupuncture points are analyzed and discussed in relation to treatment. Findings from this book can provide guidance for Chinese medicine practitioners when treating depression."

Disclaimer v
Foreword vii
Purpose of the Monograph xi
Authors and Contributors xv
Member of Advisory Committee and Panel xvii
Professor Charlie Changli Xue, PhD xix
Professor Chuanjian Lu, MD xxi
Acknowledgements xxiii
List of Figures
xxxv
List of Tables
xxxvii
1 Introduction to Unipolar Depression
1(20)
Definition and Clinical Presentation of Unipolar Depression
1(1)
Epidemiology
2(1)
Burden
2(2)
Risk Factors
4(1)
Pathological Processes
4(2)
Diagnosis
6(3)
Management
9(6)
Treatment Phases
10(1)
Acute Phase Treatment
10(1)
Continuation Phase Treatment
11(1)
Maintenance Phase Treatment
11(1)
Discontinuation of Treatment and Monitoring
12(1)
Pharmacological Treatments
12(2)
Non-pharmacological Treatments
14(1)
Prevention
15(1)
Prognosis
15(1)
References
16(5)
2 Unipolar Depression in Chinese Medicine
21(14)
Introduction
21(1)
Aetiology and Pathogenesis
22(1)
Syndrome Differentiation and Treatments
23(8)
Treatment Based on Syndrome Differentiation
24(1)
Liver Qi Stagnation
25(1)
Liver Qi Stagnation and Phlegm Stagnation
25(1)
Liver Qi Stagnation and Spleen Qi Deficiency
26(1)
Qi Stagnation Transforming into Fire
27(1)
Qi Stagnation with Blood Stasis
27(1)
Liver-Gallbladder Damp-heat
28(1)
Yin Deficiency with Fire
29(1)
Deficiency of the Heart and Spleen
30(1)
Heart and Kidney Yin Deficiency
30(1)
Melancholy Disturbing the Mind
31(1)
Acupuncture Therapies
31(2)
Acupuncture Treatment Based on Syndrome Differentiation
32(1)
Other Management Strategies
33(1)
Diet Therapy
33(1)
References
33(2)
3 Classical Chinese Medicine Literature
35(18)
Introduction
35(1)
Search Terms
36(1)
Search Procedure and Data Coding
36(1)
Data Analysis Procedure
37(1)
Search Results
38(2)
Frequency of Treatment Citations by Dynasty
39(1)
Definitions of the Condition and Aetiology
40(1)
Chinese Herbal Medicine
41(7)
Most Frequent Formulae in Depression Citations
41(2)
Most Frequent Herbs in Depression Citations
43(2)
Herbal Wash
45(1)
Combination Therapies
45(1)
Acupuncture and related Therapies
46(2)
Discussion
48(1)
Classical Literature in Perspective
49(1)
References
50(3)
4 Methods for Evaluating Clinical Evidence
53(14)
Introduction
53(1)
Search Strategy
54(3)
Inclusion Criteria
56(1)
Exclusion Criteria
57(1)
Outcomes
57(3)
Hamilton Rating Scale for Depression
57(1)
Montgomery-Asberg Depression Rating Scale
58(1)
Beck Depression Inventory
58(1)
Zung Self-rating Depression Scale
58(1)
Edinburgh Postnatal Depression Scale
59(1)
Treatment Emergent Symptom Scale
59(1)
Rating Scale for Side Effects --- Asberg
59(1)
World Health Organisation Quality of Life Scale Brief Version
59(1)
Risk of Bias Assessment
60(1)
Statistical Analyses
61(3)
Assessment Using Grading of Recommendations Assessment, Development and Evaluation
62(2)
References
64(3)
5 Clinical Evidence for Chinese Herbal Medicine
67(50)
Introduction
67(1)
Previous Systematic Reviews
67(3)
Identification of Clinical Studies
70(2)
Chinese Herbal Medicine Treatments
72(1)
Randomised Controlled Trials of Chinese Herbal Medicine
73(3)
Risk of Bias
76(1)
Results of Meta-analyses
76(1)
Hamilton Rating Scale for Depression
77(9)
Chinese Herbal Medicine vs. Placebo
77(1)
Chinese Herbal Medicine vs. Antidepressants
77(5)
Chinese Herbal Medical plus Antidepressants vs. Antidepressants: Integrative Medicine
82(4)
Chinese Herbal Medicine plus Antidepressants and Psychotherapy vs. Antidepressants plus Psychotherapy
86(1)
Zung Self-rating Depression Scale
86(1)
Chinese Herbal Medicine vs. Antidepressants
86(1)
Chinese Herbal Medicine plus Antidepressants vs. Antidepressants
87(1)
Montgomery-Asberg Depression Scale
87(1)
Chinese Herbal Medicine vs. Antidepressants
87(1)
Chinese Herbal Medicine plus Antidepressants vs. Antidepressants
87(1)
Edinburgh Postnatal Depression Scale
87(1)
Chinese Herbal Medicine vs. Placebo
88(1)
Chinese Herbal Medicine vs. Antidepressants
88(1)
Chinese Herbal Medicine plus Antidepressants vs. Antidepressants
88(1)
Chinese Herbal Medicine plus Psychotherapy vs. Psychotherapy
88(1)
Effective Rate
88(1)
Chinese Herbal Medicine vs. Antidepressants
88(1)
Chinese Herbal Medicine plus Antidepressants vs. Antidepressants
89(1)
Chinese Herbal Medicine plus Psychotherapy vs. Psychotherapy
89(1)
Assessment Using GRADE
89(3)
Randomised Controlled Trial Evidence for Individual Formulae
92(1)
Xiao yao san/wan
92(1)
Hamilton Rating Scale for Depression
92(1)
Treatment Emergent Symptom Scale
92(1)
Adverse Events
92(1)
Chai hu shu gan san
93(1)
Hamilton Rating Scale for Depression
93(1)
Adverse Events
93(1)
Dan zhi xiao yao san
93(1)
Hamilton Rating Scale for Depression
93(1)
Self-rating Depression Scale
94(1)
Side Effect Rating Scales of Asberg
94(1)
An shen ding zhi tang
94(1)
Hamilton Rating Scale for Depression
94(1)
Treatment Emergent Symptom Scale
94(1)
Adverse Events
94(1)
Bu shen shu gan hua yu tang k
95(1)
Jia wei xiao yao capsules
95(2)
Hamilton Rating Scale for Depression
95(1)
Adverse Events
95(1)
Frequently Reported Used Herbs in Meta-analyses Showing Favourable Effect
95(2)
Safety of Chinese Herbal Medicine in Randomised Controlled Trials
97(4)
Treatment Emergent Symptom Scale
97(1)
Side Effect Rating Scales of Asberg
97(1)
Adverse Events
97(2)
Chinese Herbal Medicine vs. Placebo
99(1)
Chinese Herbal Medicine vs. Antidepressants
99(1)
Chinese Herbal Medicine plus Antidepressants vs. Antidepressants
100(1)
Chinese Herbal Medicine plus Antidepressants and Psychotherapy vs. Antidepressants and Psychotherapy
100(1)
Controlled Clinical Trials of Chinese Herbal Medicine
101(1)
Hamilton Rating Scale for Depression
101(1)
Zung Self-rating Depression Scale
101(1)
Safety of Chinese Herbal Medicine in Controlled Clinical Trials
102(1)
Non-controlled Studies of Chinese Herbal Medicine
102(2)
Safety of Chinese Herbal Medicine in Non-controlled Studies
102(1)
Clinical Evidence for Commonly Used Chinese Herbal Medicine Treatments
103(1)
Ban xia hou po tang
103(1)
Gui pi tang
103(1)
Yue ju wan
104(1)
Summary of Chinese Herbal Medicine Clinical Evidence
104(1)
Chinese Herbal Medicine
105(1)
Integrative Medicine
106(1)
References
107(10)
6 Pharmacological Actions of Frequently Used Herbs
117(16)
Introduction
117(1)
Methods
118(10)
Experimental Studies on chai hu
118(1)
Experimental Studies on shao yao
119(2)
Experimental studies on gan cao
121(1)
Experimental Studies on yuan zhi
122(1)
Experimental Studies on shi chang pu
123(1)
Experimental Studies on zhi ke
124(1)
Experimental Studies on di huang
125(1)
Experimental Studies on dan shen
125(1)
Experimental Studies on Xiao yao san
126(1)
Experimental Studies on Chai hu shu gan san
127(1)
Summary of Pharmacological Actions
128(1)
References
128(5)
7 Clinical Evidence for Acupuncture and Related Therapies
133(26)
Introduction
133(1)
Previous Systematic Reviews
134(1)
Identification and Characteristics of Clinical Studies
135(2)
Risk of Bias
137(1)
Acupuncture
138(6)
Randomised Controlled Trials of Acupuncture
138(1)
Acupuncture vs. Antidepressants
138(1)
Hamilton Rating Scale for Depression
138(3)
World Health Organization Quality of Life Questionnaire
141(1)
Acupuncture plus Antidepressants vs. Antidepressants
141(1)
Hamilton Rating Scale for Depression
141(2)
Montgomery-Asberg Depression Scale
143(1)
Zung Self-rating Depression Scale
143(1)
Relapse Rate
143(1)
Controlled Clinical Trials of Acupuncture
143(1)
Non-controlled Studies of Acupuncture
143(1)
Safety of Acupuncture
144(1)
Electroacupuncture
144(5)
Randomised Controlled Trials of Electroacupuncture
145(1)
Electroacupuncture vs. Sham Electroacupuncture
145(1)
Hamilton Rating Scale for Depression
145(1)
Zung Self-rating Depression Scale
145(1)
Electroacupuncture vs. Antidepressants
145(1)
Hamilton Rating Scale for Depression
145(2)
Zung Self-rating Depression Scale
147(1)
World Health Organization Quality of Life Questionnaire
147(1)
Electroacupuncture Plus Antidepressants vs. Antidepressants
147(1)
Hamilton Rating Scale for Depression
147(1)
Zung Self-rating Depression Scale
148(1)
Electroacupuncture vs. Psychotherapy
148(1)
Electroacupuncture plus Psychotherapy vs. Psychotherapy
148(1)
Controlled Clinical Trials of Electroacupuncture
148(1)
Non-controlled Studies of Electroacupuncture
148(1)
Safety of Electoacupuncture
148(1)
Acupuncture-related Therapies
149(1)
Transcutaneous Electrical Nerve Stimulation
149(1)
Laser Therapy
150(1)
Frequently Reported Acupuncture Points in Meta-analyses Showing Favourable Effect
150(1)
Assessment Using GRADE
150(3)
Summary of Acupuncture and Related Therapies
153(1)
References
154(5)
8 Clinical Evidence for Other Chinese Medicine Therapies
159(4)
Introduction
159(1)
Previous Systematic Reviews
159(1)
Identification of Clinical Studies
159(2)
Cupping Therapy
161(1)
Tuina
161(1)
Summary of Other Chinese Medicine
161(2)
9 Clinical Evidence for Combination Therapies
163(8)
Introduction
163(1)
Randomised Controlled Trials of Combination Therapies
163(2)
Risk of Bias
165(1)
Clinical Evidence for Combination Therapies from Randomised Controlled Trials
166(3)
Acupuncture plus Chinese Herbal Medicine vs. Antidepressants
166(1)
Acupuncture plus Chinese Herbal Medicine vs. Placebo
166(2)
Acupuncture plus Tuina vs. Antidepressants
168(1)
Acupuncture plus Moxibustion vs. Antidepressants
168(1)
Acupuncture plus Moxibustion plus Five-element Music Therapy vs. Antidepressants
168(1)
Acupuncture plus Cupping plus Psychotherapy vs. Psychotherapy
168(1)
Qigong, Tuina, and Taichi plus Antidepressants vs. Antidepressants
169(1)
Controlled Clinical Trials of Combination Therapies
169(1)
Non-controlled Studies of Combination Therapies
169(1)
Summary of Combination Therapies
169(2)
10 Summary and Conclusions
171(16)
Introduction
171(1)
Chinese Medicine Syndrome Differentiation
172(1)
Chinese Herbal Medicine
173(5)
Chinese Herbal Medicine Formulae in Key Clinical Guidelines and Textbooks, Classical Literature and Clinical Studies
175(3)
Acupuncture and Related Therapies
178(2)
Other Chinese Medicine Therapies
180(1)
Limitations of Evidence
181(2)
Implications for Practice
183(1)
Implications for Research
184(1)
References
185(2)
Glossary 187(8)
Index 195