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E-raamat: Evidence-based Clinical Chinese Medicine - Volume 3: Chronic Urticaria

Editor-in-chief (Guangdong Provincial Hospital Of Chinese Medicine, China), (Rmit Univ, Australia), Editor-in-chief (Rmit Univ, Australia), (Guangdong Provincial Hospital Of Chinese Medicine, China)
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In the third volume of the Evidence-based Clinical Chinese Medicine series, the authors focus on a challenging dermatological condition chronic urticaria. Chronic urticaria can have a significant impact on quality of life, and while medical management can be effective, many people experience frequent and unpredictable recurrence.This book unearths treatments used in classical Chinese medicine textbooks, many of which are inaccessible to non-Chinese speaking Chinese medicine practitioners. Oral and topical Chinese herbal medicines used in pre-modern China for urticaria are identified, some of which are still in use today. Evidence from clinical studies has been subject to rigorous evaluation, with analyses conducted using the internationally recognized Cochrane-GRADE approach. Chinese herbal medicine formulas and acupuncture therapies which offer the most potential for treatment of chronic urticaria are highlighted.This book provides an easy to use reference for clinicians who are interested in Chinese medicine management of chronic urticaria.The authors are internationally recognized, well-respected leaders in the field of Chinese medicine and evidence-based medicine with strong track records in research.
Disclaimer v
Foreword vii
Purpose of the Monograph xi
Authors and Contributors xv
Members of the Advisory Committee and Panel xvii
Professor Charlie Changli Xue, PhD xix
Professor Chuanjian Lu, MD xxi
Acknowledgements xxiii
List of Figures
xxxi
List of Tables
xxxiii
1 Introduction to Chronic Urticaria
1(12)
Definition of Urticaria
1(2)
Clinical Presentation and Subtypes of Chronic Urticaria
1(1)
Epidemiology
2(1)
Burden
3(1)
Risk Factors
3(1)
Pathological Processes
3(2)
Diagnosis
5(1)
Management
6(2)
Pharmacological
6(2)
Non-Pharmacological
8(1)
Prognosis
8(2)
Limitations of Conventional Therapy
9(1)
References
10(3)
2 Chronic Urticaria in Chinese Medicine
13(12)
Introduction
13(1)
Aetiology and Pathogenesis
13(1)
Syndrome Differentiation and Treatments
14(1)
Oral Chinese Herbal Medicine Treatment Based on Syndrome Differentiation
15(6)
Exterior Heat Syndrome
15(1)
Exterior Cold Syndrome
16(1)
Dampness-heat in Stomach and Intestine
17(1)
Defense-exterior Insecurity
18(1)
Dual Deficiency of qi and Blood
19(1)
Qi--Blood Stagnation and Stasis
20(1)
Blood Deficiency and Wind-dryness
20(1)
Topical Chinese Herbal Medicine Treatment
21(1)
Acupuncture Therapies and Other Chinese Medicine Therapies
22(1)
Other Management Strategies
23(1)
References
24(1)
3 Classical Chinese Medicine Literature
25(18)
Introduction
25(1)
Search Terms
26(1)
Search Procedure and Data Coding
26(1)
Data Analysis Procedure
27(1)
Search Results
28(2)
Citations Related to Urticaria
29(1)
Definitions of Urticaria and Aetiology
29(1)
Chinese Herbal Medicine
30(10)
Frequency of Treatment Citations by Dynasty
30(1)
Symptoms Described in Treatment Citations
31(1)
Treatment with Chinese Herbal Medicine
31(1)
Most frequent formulae in possible urticaria citations
31(1)
Most frequent herbs in possible urticaria citations
32(1)
Most frequent formulae in most likely urticaria citations
32(6)
Most frequent herbs in most likely urticaria citations
38(1)
Discussion
39(1)
Acupuncture and Related Therapies
40(1)
Discussion
40(1)
Classical Literature in Perspective
41(1)
References
42(1)
4 Methods for Evaluating Clinical Evidence
43(12)
Introduction
43(1)
Search Strategy
44(1)
Inclusion Criteria
45(2)
Exclusion Criteria
47(1)
Outcomes
47(1)
Risk of Bias Assessment
48(2)
Statistical Analyses
50(1)
Assessment Using Grading of Recommendations Assessment, Development and Evaluation
50(2)
References
52(3)
5 Chinese Herbal Medicine
55(36)
Introduction
55(1)
Previous Systematic Reviews
56(1)
Characteristics of Chinese Herbal Medicine Clinical Studies
56(2)
Randomised Controlled Trials of Chinese Herbal Medicine
58(25)
Risk of Bias
63(1)
Disease Activity: Urticaria Activity Score
64(1)
Health-related Quality of Life: Dermatology Life Quality Index
64(1)
Effective Rate
65(2)
Relapse Rate
67(1)
Symptom Severity Reduction Index
68(2)
Assessment Using Grading of Recommendations Assessment, Development and Evaluation
70(2)
Chinese herbal medicine vs. second-generation antihistamines
72(1)
Chinese herbal medicine as integrative medicine vs. second-generation antihistamines
72(1)
Randomised Controlled Trial Evidence for Individual Formulae
72(7)
Randomised Controlled Trial Evidence from Formulae Commonly Used in Clinical Practice
79(1)
Frequently Reported Herbs in Meta-Analyses Showing Favourable Effect
80(1)
Safety of Chinese Herbal Medicine in Randomised Controlled Trials
80(3)
Controlled Clinical Trials of Chinese Herbal Medicine
83(2)
Controlled Clinical Trial Evidence for Individual Formulae
84(1)
Controlled Clinical Trial Evidence for Formulae Commonly Used in Clinical Practice
85(1)
Safety of Chinese Herbal Medicine in Controlled Clinical Trials
85(1)
Clinical Evidence from Non-Controlled Studies
85(6)
Non-Controlled Studies of Individual Formulae
86(1)
Non-Controlled Studies of Formulae Used in Clinical Practice
86(1)
Safety of Chinese Herbal Medicine in Non-Controlled Studies
87(1)
Summary of Chinese Herbal Medicine Clinical Evidence
88(1)
References
89(2)
6 Pharmacological Actions of the Frequently Used Herbs
91(16)
Introduction
91(1)
Experimental Studies on Fang Feng
91(1)
Experimental Studies on Can Cao
92(1)
Experimental Studies on Dang Gui
93(1)
Experimental Studies on Jing Jie
94(1)
Experimental Studies on Huang Qi
94(1)
Experimental Studies on Di Huang
95(1)
Experimental Studies on Bai Zhu
95(1)
Experimental Studies on Bai Shao
96(1)
Experimental Studies on Chan
97(1)
Experimental Studies on Bai Xian Pi
97(1)
Experimental Studies on Mu Dan Pi
98(1)
Experimental Studies on Herbal Formulae
99(1)
Summary of Pharmacological Actions of the Common Herbs
100(1)
References
100(7)
7 Clinical Evidence for Acupuncture and Related Therapies
107(14)
Introduction
107(1)
Previous Systematic Reviews
108(1)
Characteristics of Acupuncture and Related Therapies Clinical Studies
108(2)
Randomised Controlled Trials of Acupuncture and Related Therapies
110(8)
Risk of Bias
110(1)
Acupuncture
111(1)
Acupuncture alone
112(1)
Acupuncture as integrative medicine
112(1)
Acupuncture plus moxibustion as integrative medicine
112(1)
Frequently reported acupuncture points in meta-analyses showing favourable effect: acupuncture
113(1)
Assessment using GRADE
113(1)
Acupuncture versus second-generation antihistamines
113(3)
Acupuncture as integrative medicine vs. second-generation antihistamines
116(1)
Moxibustion
116(1)
Moxibustion alone
116(1)
Assessment using GRADE
116(2)
Randomised Controlled Trial Evidence for Interventions Commonly Used in Clinical Practice
118(1)
Clinical Evidence from Controlled Clinical Trials
118(1)
Clinical Evidence from Non-Controlled Studies
118(1)
Non-Controlled Trial Evidence for Interventions Commonly Used in Clinical Practice
118(1)
Summary of Acupuncture and Related Therapies Clinical Evidence
119(1)
References
119(2)
8 Clinical Evidence for Combination Therapies
121(6)
Introduction
121(1)
Randomised Controlled Trials of Combination Therapies
121(3)
Risk of Bias
123(1)
Results of Combination Therapies
124(1)
Safety of Combination Therapies
124(1)
Summary of Combination Therapies Evidence
124(3)
9 Summary and Conclusions
127(12)
Introduction
127(1)
Chinese Herbal Medicine
128(4)
Chinese Herbal Medicine Formulae in the Contemporary and Classical Literature, and Clinical Studies
129(3)
Acupuncture and Related Therapies
132(1)
Acupuncture Therapies in the Contemporary and Classical Literature, and Clinical Studies
133(1)
Implications for Practice
133(2)
Implications for Research
135(2)
Clinical Trial Design
136(1)
References
137(2)
Appendix 1 All Included Clinical Studies 139(12)
Glossary 151(14)
Index 165