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E-raamat: Exploring the Frontiers of Innovation to Tackle Microbial Threats: Proceedings of a Workshop

  • Formaat: 178 pages
  • Ilmumisaeg: 10-Aug-2020
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309675369
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  • Formaat: 178 pages
  • Ilmumisaeg: 10-Aug-2020
  • Kirjastus: National Academies Press
  • Keel: eng
  • ISBN-13: 9780309675369

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On December 4-5, 2019, the National Academies of Sciences, Engineering, and Medicine held a 1.5-day public workshop titled Exploring the Frontiers of Innovation to Tackle Microbial Threats. The workshop participants examined major advances in scientific, technological, and social innovations against microbial threats. Such innovations include diagnostics, vaccines (both development and production), and antimicrobials, as well as nonpharmaceutical interventions and changes in surveillance. This publication summarizes the presentations and discussions from the workshop.

Table of Contents



Front Matter 1 Introduction 2 Pivotal Role of Innovations in Tackling Microbial Threats: Lessons from Past Outbreaks 3 Harnessing Lessons from Emerging Scientific, Technological, and Social Innovations 4 Overcoming Barriers in the Field to Bolster Access and Practical Use of Innovations 5 Systems Approaches to Spur Innovations in Tackling Antimicrobial Resistance 6 Breaking Down Barriers and Fostering Partnerships to Enable Innovation 7 Nurturing Innovations Through Novel Ecosystems to Accelerate Research and Development 8 Visionary Statements on Priorities for Innovation References Appendix A: Workshop Statement of Task Appendix B: Workshop Agenda Appendix C: Speaker Biographies
Acronyms And Abbreviations xix
1 Introduction
1(4)
Workshop Objectives
2(1)
Organization of the Proceedings of the Workshop
3(2)
2 Pivotal Role Of Innovations In Tackling Microbial Threats: Lessons From Past Outbreaks
5(14)
Lessons Learned from Innovation in Polio Eradication
5(4)
Advancing Innovation on the Ground in the Fight Against Ebola
9(6)
Discussion
15(4)
3 Harnessing Lessons From Emerging Scientific, Technological, And Social Innovations
19(18)
The Role of Innovation in the Evolution of Global Vector Control Response
20(3)
Applying Modeling to Inform Infectious Disease Surveillance and Outbreak Response
23(4)
Unbiased Metagenomics Sequencing to Counter Microbial Threats: Lessons from Bangladesh
27(3)
Digital Process Innovations for HIV Self-Testing
30(3)
Discussion
33(4)
4 Overcoming Barriers In The Field To Bolster Access And Practical Use Of Innovations
37(22)
Digital Innovation to Improve Immunization Service Delivery
38(2)
Using Data and Modeling to Improve Detection and Response
40(3)
Outbreak-Related Data Sharing and Collaboration: Challenges and Opportunities
43(5)
Addressing Health Challenges with Behavioral Insights and Tools
48(6)
Discussion
54(5)
5 Systems Approaches To Spur Innovations In Tackling Antimicrobial Resistance
59(20)
Applying Lessons from One Health Surveillance to Tackle Antimicrobial Resistance
60(4)
Sparking Antibiotic Discovery Through Data Sharing and Scientific Collaboration
64(3)
Incentivizing Novel Diagnostic Tests to Counter Antibiotic Resistance
67(3)
Strengthening Systems to Overcome Barriers to Innovation
70(4)
Discussion
74(5)
6 Breaking Down Barriers And Fostering Partnerships To Enable Innovation
79(16)
Enabling Biotechnologies Through Partnerships
80(2)
Fostering New Partnerships to Enable Innovation
82(4)
Private-Sector Partnerships to Address Global Health Needs
86(2)
Discussion
88(7)
7 Nurturing Innovations Through Novel Ecosystems To Accelerate Research And Development
95(22)
Biomedical Advanced Research and Development Authority
95(2)
Decoding the Human Immune System to Transform Human Health
97(3)
Reverse Innovation
100(3)
Nurturing Innovation to Accelerate Research and Development
103(3)
Spurring Innovation in Diagnostic Tools
106(5)
Discussion
111(6)
8 Visionary Statements On Priorities For Innovation
117(18)
Innovations Against Vector-Borne Diseases in Brazil
117(1)
Innovations to Address Antimicrobial Resistance in Canada
118(2)
Innovations to Maximize Impact in AIDS, Tuberculosis, and Malaria
120(2)
Final Synthesis and Discussion
122(3)
References
125(10)
APPENDIXES
A Workshop Statement Of Task
135(2)
B Workshop Agenda
137(6)
C Speaker Biographies
143