The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed—whether natural and synthetic—and the improvement, such as modifications of synthetic approach and polymerization technique, of their physicochemical and biological properties to synthetize high performing carriers for specific uses, i.e. stimuli-responsive materials, molecularly imprinted polymers, mucoadhesive materials, carrier for the delivery of high molecular weight drugs, and gene-delivery.
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1 Design of Stimuli-Responsive Drug Delivery Hydrogels: Synthesis and Applications |
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1 | (23) |
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2 Nanocomposite Hydrogels as Drug Delivery Systems |
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24 | (28) |
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Teresa del Castillo Castro |
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Maria Monica Castillo Ortega |
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Dora Evelia Rodriguez Felix |
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Jose Carmelo Encinas Encinas |
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3 Vesicles, Micelles and Cyclodextrins Immobilized into Hydrogel: Multi-component Devices for Controlled Drug Delivery |
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52 | (12) |
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4 Molecularly Imprinted Hydrogels for the Selective Release of Therapeutics |
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64 | (24) |
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5 Prodrugs and Bioconjugate Hydrogels: A Valuable Strategy for the Prolonged-Delivery of Drugs |
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88 | (25) |
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6 Carbohydrate based Hydrogels for Controlled Release of Cancer Therapeutics |
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113 | (41) |
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7 Porous Hydrogels as Carrier for Delivery of Macromolecular Drugs |
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154 | (43) |
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8 Biopolymer-based Interpenetrating Network Hydrogels for Oral Drug Delivery |
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197 | (37) |
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9 Stimuli-Responsive Hydrogels for Parenteral Drug Delivery |
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234 | (25) |
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10 Hydrogels for Vaginal Drug Delivery |
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259 | (44) |
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11 Advances in Composite Hydrogels for Ocular Drug Delivery and Biomedical Engineering Application |
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303 | (24) |
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12 Hydrogels for Pulmonary Drug Delivery |
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327 | (26) |
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| Index |
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353 | |
Spizzirri received his degree in Chemistry cum laude in 2001 and his PhD in 2005 from the University of Calabria. He is currently a member of the Department of Pharmacy, Health and Nutrition Science of the same University. His teaching experience comes from tutorial activity for Pharmaceutical Technology and Commodity Economics Science and as a professor of Systems for Pharmaceutical Industry and Food Chemistry. In 2004, he was visiting researcher at the University of Texas at Austin. His research activities are mainly related to polymer chemistry and technology for the preparation of stimuli-responsive drug delivery systems, functional polymer for food industry, and new analytical methodologies for food quality and safely assessment. He is author and coauthor of more than 90 publications, including research and review articles as well as invited book chapters.
Cirillo received his degree in Pharmaceutical Chemistry and Technology cum laude in 2005 and his PhD in Methodologies for the Development of Molecules of Pharmaceutical Interest in 2008 from University of Calabria. He is currently in a post-doctoral position at the same University. He was tutor for Pharmaceutical Technology and Commodity Economics Science and a Contract professor of Chemistry and Biotechnology of Fermentations at the Faculty of Pharmacy, Nutritional and Health Sciences of University of Calabria. His research interests are the development of functional polymers with tailored biological activity, the design of smart hydrogels for drug delivery, the study of the activity of innovative functional foods and nutraceuticals, and the synthesis and functionalization of carbon nanotubes-based devices for biomedical applications. During 2008 and from 2012 to 2014, he was visiting researcher at Leibniz Institute for Solid State and Materials Research Dresden (Germany). He is author and co-author of more than 80 publications, including research and review article as well as invited book chapters.
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