As exciting as the new field of genomics is, it has not yet produced a basicconceptual change in biology. The fundamental problems remain: the origin of life, cellorganization, the pathways of differentiation, aging, and the molecular and cellular capabilities ofthe brain. What has occurred is an explosion of molecular information obtained by genomic sequences,which will soon be followed by exhaustive catalogs of protein interactions and protein function.This wealth of information can be analyzed and manipulated only with the help of computers. Therapidly expanding role of computers in biology may usher in a profound conceptual change in how westudy living systems in the laboratory.This book focuses on current computational approaches tounderstanding the complex networks of metabolic and gene regulatory capabilities of the cell. Thecontributors look well beyond the state of the art in computational biology to anticipate whatbiological research will be like in a post-genomic world.
An overview of current computational approaches to metabolism and gene regulation.
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