E-raamat: Genomics and Health in the Developing World

Contributors ; Part I: Genomics in Medicine and Health-General ;
1.
Genes and Genomes in Health and Disease: An Introduction ; Dhavendra Kumar ;
2. The Human Variome Project and the Developing World ; Richard G.H. Cotton ;
3. Human Genomic Variation Initiatives in Emerging Economies and Developing
Countries ; Beatrice Seguin, Billie-Jo Hardy, Peter A. Singer, and Abdallah
S. Daar ;
4. The Genomic Map of Population Diversity in Asia ; Dhavendra
Kumar ;
5. Ancestry, Disease and Variable Drug Response in the Genomic Era ;
Charles Rotimi and Lynn Jorde ;
6. The Next Steps for Genomic Medicine:
Challenges and Opportunities for the Developing World ; Billie-Jo Hardy,
Beatrice Seguin, Federico Goodsaid, Gerardo Jimenez-Sanchez, Peter A. Singer,
and Abdallah S. Daar ;
7. Consumer Perspectives on Genomics and Healthcare ;
Alastair Kent ;
8. Transcultural Perspectives on Genetics and Genomics ;
Dhavendra Kumar ;
9. Medical Genetics and Genomics Research in the Muslim
World ; Aida I. Al-Aqeel ;
10. The Progress of Genomics in the Developing
World: Rising Social, Economic, and Ethical Concerns ; Minakshi Bhardwaj ;
11. Genetic Outcomes of Consanguineous Marriages ; Alan H. Bittles and
Michael L. Black ;
12. Autosomal Recessive Conditions and Autozygosity
Mapping ; Colin A. Johnson and Eamonn R. Maher ;
13. Genetic Contribution to
Malaria Susceptibility and Resistance ; Susana G. Campino and Taane G. Clark
;
14. Glucose 6-Phosphate Dehydrogenase Deficiency: Genetics,
Pharmacogenetics, and Malaria Selection ; Lucio Luzzatto ;
15. Infections,
Genomics, and Global Public Health ; Tikki Pang ;
16. Microbial Genomics and
Global Health ; Rino Rappuoli ;
17. Pharmacogenetics and Pharmacogenomics in
the Developing World ; Warren E. Hochfeld, Sahle M. Asfaha, Marco
Alessandrini, Tyren M. Dodgen, Renier Myburgh, Arinda Eloff, and Michael S.
Pepper ;
18. Nutrigenomic Research in World Populations ; Jim Kaput ;
19.
Transgenic Foods and Nutritional Health in Developing Countries ; Dhavendra
Kumar and Joel Cohen ;
20. The Burden of Inherited Disease in the Developing
World: The Example of Inherited Blood Diseases ; David J. Weatherall ;
21.
Health Implications of Inherited Disorders of Iron Overload ; Chun Yo Lok,
Alison T. Merryweather-Clarke, and Kathryn J.H. Robson ;
22. Inherited
Factors in Diabetes Mellitus and Related Metabolic Disorders in the
Developing World ; Dwaipayan Bharadwaj, Nikhil Tandon, and Anubha Mahajan ;
23. Global Health Implications of Genetic Studies of Obesity and Type 2
Diabetes ; Jessica Buxton, Julia El-Sayed Moustafa, Haya Al-Saud, and
Alexandra Blakemore ;
24. Health Implications of Familial Hyperlipidemia ;
Deepak Bhatnagar ;
25. Global Health Implications of Inherited Renal Diseases
; Wendy Jones and Anand Saggar ;
26. The Burden of Congenital Anomalies on
Global Health ; Dhavendra Kumar ;
27. Inherited Eye Diseases in Developing
Countries ; Tiziana Cogliati, James Friedman, Norimoto Gotoh, Neeraj Agarwal,
and Anand Swaroop ;
28. Principles and Practice of Newborn Screening-The
Lessons from the Developed World ; Rodney J. Pollitt ;
29. Diagnostic
Laboratory Genetic Testing - Models for the Developing World ; Peter Lunt ;
30. Ethical Issues Arising in Medical Genetics in Developing Countries ;
Angus Clarke ;
31. Genetic and Genomics Services in Emerging Economies of the
Developing World ; Robert George Elles ; Part II: Genomics in Medicine and
Health-Regional ; Africa ;
32. Anthropology and Population Heterogeneity in
North Africa ; Rym Kefi ;
33. The Genetic Landscape of Sub-Saharan African
Populations ; Himla Soodyall and Carina M. Schlebusch ;
34. Genetic Disorders
in North African Populations ; Romdhane Lilia and Abdelhak Sonia ;
35.
Genetic Neurological Diseases in Tunisia ; Neziha Gouider-Khouja and Ibtihel
Rebai ;
36. Hemoglobinopathies in Africa ; Ambroise Wonkam and Amanda Krause
;
37. The Burden of Birth Defects and Genetic Disease in Sub-Saharan Africa ;
Ambroise Wonkam ;
38. Genetic Epidemiology of South Atlantic Oceanic Islands
; Peter Beighton ;
39. Genetic Disorders in Minority Groups in South Africa ;
Peter Beighton ;
40. Hereditary Deafness in Southern Africa ; Peter Beighton
and Sean Sellars ;
41. Heritable Disorders of the Skeleton in South Africa ;
Peter Beighton ;
42. Heritable Disorders of Connective Tissue in South Africa
; Peter Beighton ;
43. Genetic Perspectives of Tuberculosis in Southern
Africa ; Erika de Wit, Marlo Moller, and Eileen Hoal ;
44. Familial Cancer
Syndromes in Africa ; Yonglan Zheng, Toshio F. Yoshimatsu, and Olufunmilayo
I. Olopade ;
45. Genetic Counseling in South Africa ; Jacquie Greenberg,
Jennifer Kromberg, Kelly Loggenberg, and Tina-Marie Wessels ;
46. Prenatal
Diagnostic Services and Prevention of Birth Defects in South Africa ; Michael
Urban and Lut Geerts ;
47. Sociocultural Perspectives of Inherited Diseases
in Southern Africa ; Claire Penn and Jennifer Watermeyer ;
48. Ethical,
Legal, and SocioCultural Issues and Genetic Services in Southern Africa ;
Jennifer G.R. Kromberg and Trefor Jenkins ;
49. The Genomic Research and
Health Applications in South Africa ; Billie-Jo Hardy, Beatrice Seguin, Raj
Ramesar, Peter A. Singer and Abdallah S. Daar ; Arab and Middle East ;
50.
Hereditary Disorders in Arabs ; Ghazi Omar Tadmouri and Mahmoud Taleb Al Ali
;
51. Community Health Implications of Consanguinity in Arab Populations ;
Ghazi O. Tadmouri, Pratibha Nair, Tasneem Obeid, and Hanan Hamamy ;
52.
Clinical Dysmorphology in the Arab World ; Lihadh Al-Gazali and Hanan Hamamy
;
53. The Population Genetics and Hereditary Diseases of Bahrain ; Shaikha
Salim Al-Arrayed ;
54. Genetic Diseases in the Sultanate of Oman ; Anna Rajab
and Michael A.Patton ;
55. Genetic Disorders in Lebanon: Challenges and
Opportunities ; Issam I. Khneisser, Salim. M. Adib, and Andre Megarbane ;
56.
Genetic Disease in Palestine and Palestinians ; Bassam Abu-Libdeh, Peter D.
Turnpenny, and Ahmed Teebi ;
57. Genetic Skin Diseases in the Arab World ;
Mourad Mokni, Cherine Charfeddine, and Sonia Abdelhak ;
58. Hereditary
Diseases of the Nervous System in Arabs ; Nisrine Bissar-Tadmouri, Mohamad
Al-Homssi, and Pratiba Nair ;
59. Preimplantation Genetic Diagnosis in Saudi
Arabia ; Serdar Coskun, Wafa Qubbaj, and Aida I. Al-Aqeel ; Asia-Pacific ;
60. Genomics for Universal Healthcare in Thailand ; Beatrice Seguin,
Billie-Jo Hardy, Peter A. Singer, and Abdallah S. Daar ;
61. Screening
Newborns in the Asia-Pacific Region ; Carmencita D. Padilla and Bradford L.
Therrell ;
62. Clinical Dysmorphology and Birth Defects Registry in the
Asia-Pacific Region ; Meow Keong Thong ;
63. Prevention and Control of
Thalassemia in Thailand ; Chanane Wanapirak, Jintana Pattanapongthorn, Pranee
Winichagoon, and Suthat Fucharoen ;
64. Inherited Metabolic Disorders in
Thailand and the Asia-Pacific ; Pornswan Wasant ;
65. Genetic Skeletal
Dysplasias in Thailand ; Pornswan Wasant ;
66. Medical Genetic Services in
the Philippines ; Carmencita Padilla, Eva Maria Cutiongco-de la Paz, and
Catherine Lynn Silao ; Chinese Subcontinent ;
67. Community and Public Health
Genetics in China ; Manshu Song, Youxin Wang, Lijuan Wu, Yun Wang, and Wei
Wang ;
68. Genetic Epidemiology in China ; Peng-Gao Li, Yan He and Wei Wang ;
69. Traditional Chinese Medicine in the Area of Genomics ; Hong-Min Yun,
Manshu Song, and Wei Wang ;
70. Inherited Factors in Cardiovascular Disease
in China ; Ling Zhang Ying Dai, and Wei Wang ;
71. Familial and Genetic
Cancer in China ; Fen Liu and Wei Wang ;
72. Genomic Medicine in Taiwan:
Research and Developments ; Ming Ta Michael Lee, Chien-Hsiun Chen, and
Yuan-Tsong Chen ; Indian Subcontinent ;
73. The Indian Subcontinent and its
People ; Dhavendra Kumar ;
74. Genomic Perspectives of Peopling and Languages
of the Indian Subcontinent ; Ganesh Prasad Arunkumar, Varatharajan
Santhakumari Arun, Adhikarla Syama, Valampuri John Mary Selvam Kavitha, and
Ramasamy M. Pitchappan ;
75. Genomic Diversity of HLA in the Indian
Subcontinent ; Narinder K. Mehra and Gurvinder Kaur ;
76. Genomic
Applications in Medicine and Health in India ; Billie-Jo Hardy, Beatrice
Seguin, Peter A. Singer, Mitali Mukerji, Samir K. Brahmachari and Abdallah S.
Daar ;
77. Epidemiology of Genetic Diseases in the Indian Subcontinent ;
Ishwar C. Verma and Dhavendra Kumar ;
78. Genetic Services in India: A Model
for Developing Countries ; Ratna D. Puri and Ishwar C. Verma ;
79. The
Practice of Genetic Counseling in India ; Meenakshi Bhatt ;
80. Social and
Cultural Aspects of Customary Consanguineous Marriages in South Asia ; Rafat
Hussain ;
81. Medical Genetics and Genomics in Sri Lanka ; Vajira H.W.
Dissanayake ;
82. Inherited Factors in Obstructive Lung Diseases in India ;
Amrendra Kumar Gupta, Balaram Ghosh, and Anurag Agrawal ;
83. Inherited
Metabolic Disease in India ; Bal N. Apte ;
84. Genetic Variation and Genetic
Epidemiology of Sri Lanka ; Deepthi C. de Silva ;
85. Familial Cancer and
Cancer Genetics in the Indian Subcontinent ; Dhavendra Kumar ;
86. Inherited
Disorders of the Eye in the Indian Subcontinent ; Govindasamy
Kumaramanickavel ;
87. Type 2 Diabetes Mellitus in India ; Radha Venkatesan,
Kanthimathi Sekar and Viswanathan Mohan ;
88. Hereditary Spinocerebellar
Ataxias in India ; Mohammed Faruq, Uma Mittal, Achal K. Srivastava, and
Mitali Mukerji ;
89. Malformation Syndromes in India ; Shubha Phadke ;
90.
Thalassemias and Abnormal Hemoglobins of the Indian Subcontinent ; John Old ;
91. The Management of Inherited Blood Diseases in the Indian Subcontinent ;
Reena Das ;
92. Conventional and Molecular Cytogenetics in India ; Prochi F.
Madon ;
93. Genetic Studies of Parkinson's Disease in India ; Jharna Ray ;
94. The Genetic Basis of Alcoholism in India ; Meera Vasani ;
95. The
Genetics of Autism in India ; G.K. Chetan, K.R. Manjunatha, Sam Balu, H.N.
Venkatesh, and S.C. Grimaji ;
96. The Genetics of Leprosy in India ;
Mariakuttikan Jayalakshmi, Narayanan Kalyanaraman, and Ramasamy Pitchappan ;
97. The Current Status of Medical Genetics in India ; Neerja Gupta and
Madhulika Kabra ;
98. The Indian Landscape of Human/Medical Genetics Research
and Service ; Swati Naik, Arvind Rup Singh, and Jai Rup Singh ; Latin America
and the Caribbean ;
99. Design and Implementation of a Platform for Genomic
Medicine in Mexico ; Gerardo Jimenez-Sanchez, Julio Frenk, and Guillermo
Soberon ;
100. Anthropological and Medical Implications of Genetic Admixture
in the Mexican Mestizo Population ; Ricardo M. Cerda-Flores and Augusto
Rojas-Martinez ;
101. Medical and Human Genetics in Ecuador ; Cesar
Paz-y-Mino ;
102. The Brazilian Ancestrome ; Sergio D.J. Pena ;
103. The
Practice of Medical Genetics in Brazil ; Dafne Dain Gandelman Horovitz,
Antonia Paula Marques-de-Faria, and Victor Evangelista de Faria Ferraz ;
104.
Population Medical Genetics in Brazil ; Lavinia Schuller-Faccini and Roberto
Giugliani ;
105. Medical Genetic Services in Latin America: Focus in
Argentina ; Victor B. Penchaszadeh ;
106. Hereditary Ataxias in Cuba ; Luis
Velazquez-Perez, Jose Miguel Laffita-Mesa, and Roberto Rodriguez-Labrada ;
107. Latin American School of Human and Medical Genetics and Latin American
Network of Human Genetics: promoting education, interaction and networking
across Latin America ; Roberto Giugliani, Guilherme Baldo, and Ursula Matte ;
Russia, Central Asia, and Europe ;
108. Genetic Legacy of Populations in
Eurasia ; I.A. Kutuev, B.B. Yunusbayev, and E.K. Khusnutdinova ;
109. MtDNA
and Y-chromosomal Variation in Populations of Sakha (Yakutia) ; Sardana A.
Fedorova, Elza K. Khusnutdinova, and Richard Villems ;
110. Epidemiology of
Hereditary Diseases in the European Sector of Russia ; E.K. Ginter and R.A.
Zinchenko ;
111. Hereditary Diseases among the Yakuts ; Nadezda R. Maksimova
and Anna N. Nogovitsina ;
112. Hereditary Diseases in Siberian Populations ;
Ludmila P. Nazarenko and V.P. Puzyrev ;
113. Hereditary Diseases in the
Volga-Ural Region of Russia ; Irina M. Khidiyatova, Irina R. Gilyazova, Vita
L. Akhmetova and Elza K. Khusnutdinova ;
114. Inherited Neuropsychiatric
Disorders in Russia ; D. Gaysina, A. Zainullina, and E. Khusnutdinova ;
115.
Genetic and Genomic Perspectives of Medical and Health Education in Hungary ;
Bela Melegh ;
116. Human and Medical Genetics in Hungary ; Bela Melegh ;
117.
The Genetics of Alcohol Dependence in Russia ; A. Kazantseva, G.
Faskhutdinova, and E. Khusnutdinova ;
118. Medical Genetics Teaching and
Training in Russia ; S.I. Kozlova and E.K. Ginter ;
119. Ethical and Legal
Aspects of Medical Genetics in Russia ; V.L. Izhevskaya and V.I. Ivanov ;
120. Bioethical Aspects of Genetics and Genomics in Yakut (Siberia) ; S.K.
Kononova, S.A. Fedorova, and E. Khusnutdinova ;
121. Inherited Metabolic
Diseases among Migrant Ethnic Populations in the United Kingdom ; Anupam
Chakrapani and Maureen Cleary ;
122. Views of Inherited illness among British
Pakistani Users of Genetic Services ; Alison Shaw and Jane Hurst ;
123.
Social, Cultural, and Religious Issues Related to Genetic Diseases among the
Bangladeshis in the UK ; Santi Rozario and Sophie Gilliat-Ray

Dhavendra Kumar, MD, FRCP, FACMG, is Professor, the University of Glamorgan, and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom.