"Greenfield's is the world's leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The two volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Expert coverage from an international team of Editors and contributors ensures authoritative and up to date content. The two volume set includes a downloadable and easily used e-version. This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease"--
Greenfield's 10e is the world’s leading neuropathology reference.The two volume work provides a comprehensive account of the pathological findings in neurological disease,their biological basis,and their clinical manifestations.The key reference for scientists, clinicians, researchers, and students who wish to learn about neurological disease.
Greenfield's is the world’s leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The two volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Expert coverage from an international team of Editors and contributors ensures authoritative and up to date content. The two volume set includes a downloadable and easily used e-version.
This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease.
Volume One. Section 1: General Pathology of the Nervous System. Diseases
of brain synapses and neuronal architecture. Astrocyte functions in health
and disease. Oligodendrocytes. Microglia. Ependymal cells and choroid plexus.
Cellular inclusions and artefacts. Basic Pathophysiology. Section 2:
Cerebrovascular Disorders.Vascular disease, hypoxia and consequences. Section
3: Developmental Neuropathology and Metabolic Disorders. Normal development
of the nervous system. Acquired disorders of childhood. Malformations.
Metabolic and degenerative disorders of childhood. Lysosomal disorders.
Peroxisomal disorders,Mitochondrial disorders. Section 4: Epilepsy.Epilepsy
pathology. Section 5: Neuroinflammatory Disorders Demyelinating
disorders.Immune-related disorders.Section 6: Neurodegenerative
disorders.Neurodegenerative diseases:classification. Pathogenesis and
concepts. Movement disorders. Degenerative ataxic disorders. Motor neurone
disorders.Cognitive decline.PrP proteinopathies. Alzheimers disease (A-beta
and Tau proteinopathy). Synuclein proteinopathies.Tau proteinopathies. TDP-43
proteinopathies.FUS/FET proteinopathies.Trinucleotide repeat disorders.
Miscellaneous proteinopathies and neurodegenerative conditions.
Ageing-related pathologies of the brain. Mixed pathologies of the ageing and
neurodegenerating brain.Diagnostic approach to the neuropathology of
neurodegenerative diseases.
Volume Two. Section 7:Infections of the Nervous System.Viral infections of
the nervous system. Bacterial, fungal, protozoal and parasitic infections of
the nervous system.Section 8: Nutritional and Toxic Disorders. Nutritional
and toxic disorders.Section 9: Neurotrauma. The neuropathology of traumatic
brain injury Section 10: Neuro-oncology. Introduction to tumours. Adult-type
diffuse gliomas. Paediatric-type diffuse gliomas. Circumscribed astrocytic
gliomas. Glioneuronal and neuronal tumours. Ependymal tumours. Choroid plexus
tumours. Embryonal tumours. Pineal tumours. Tumours of the peripheral nerves.
Meningiomas. Mesenchymal non-meningothelial tumours. Germ cell tumours.
Melanocytic tumours. Lymphomas and haematopoietic neoplasms. Pituitary and
suprasellar tumours. Cysts and tumour-like conditions. Metastatic disease.
Hereditary tumour syndromes. CNS reactions to anti-neoplastic
therapies.Section 11: Psychiatric and Neurodevelopmental Disorders Pathology
of psychiatric and neurodevelopmental disorders.Section 12: Neuromuscular
Disorders Peripheral nerve pathology. Skeletal muscle disorders
Professor Colin Smith, Chair of Neuropathology, Centre for Clinical Brain Sciences,Centre for Comparative Pathology,The University of Edinburgh, Scotland, UK. Graduated MBChB from Glasgow 1992, and FRCPath 2000. Appointed Senior Lecturer in Pathology in 2001 and has both a diagnostic and research component to his role. Main research interests lie around neurotrauma and neurovascular disease, and particularly assessment of human tissue in these disorders. Professor Tom Jacques, Professor of Paediatric Neuropathology, ICH Development Bio & Cancer Programme,UCL GOS Institute of Child Health, London, UK. Gabor G Kovacs, MD, PhD, FRCPC is Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, a Consultant Neuropathologist at the Laboratory Medicine Program (LMP) at the University Health Network (UHN) and a Principal Investigator at the Tanz Centre for Research in Neurodegenerative Disease. He is also a Senior Scientist at the Krembil Brain Institute, a Faculty member of the Edmond J. Safra Program in Parkinson's Disease and the Co-Director of the Rossy Program for Progressive Supranuclear Palsy Research (UHN).
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