Intended for researchers and graduate students in the biology of ageing, this book provides a general overview of biomedical gerontology and an update to previous editions. It focuses on three major sources of influence on ageing: biological, psychological and social.
Part 1 Introduction to ageing: demography and epidemiology of ageing in
the United States, D.B. Brock, et al; ageing in protoxoa, J. Smith-Sonneborn;
caenorhabditis elegans offers the potential for molecular dissection of the
ageing processes, T.E. Johnson. Part 2 Methodology for biological ageing
studies: design, conduct and analysis of human ageing research, J.W. Rowe, et
al; animal models in ageing research, E.J. Masoro. Part 3 Molecular and
cellular ageing: alternations in gene expression with ageing, D.B.Danner and
N.J. Holbrook; modifications of proteins and nucleic acids by reducing sugars
- possible role in ageing, A.T. Lee and A.H. Cerami; ageing at the cellular
level - the human fibroblastlike cell model, T.H. Norwood, et al. Part 4
Physiology of ageing: ageing and the immune response, R.A. Miller; heart and
circulation, E.G. Lakatta. Part 5 Neurobiology: age-related changes in
synaptic neurochemistry - 1983-1988, D.G. Morgan and P.C. May; synaptic
plasticity, neurotrophic factors, and transplantation in the aged brain, C.W.
Cotman; circadian rhythms and ageing, G.S. Richardson; central nervous system
disorders in ageing, T.B. Horvath and K.L. Davis; the adrenocortical axis,
R.M. Sapolsky. Part 6 Human biology: pharmacology and ageing, R.E. Vestal and
B.J. Cusack; nutrition and ageing, L.M. Ausman and R.M. Russell; physical
exercise in the elderly, A.P. Goldberg and J.M. Hagberg; chemical senses and
ageing, L.M. Bartoshuk and J.M. Weiffenbach.
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