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E-raamat: Handbook of Metallonutraceuticals

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  • Formaat: 350 pages
  • Sari: Nutraceuticals
  • Ilmumisaeg: 28-Apr-2014
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781040210192
  • Formaat - EPUB+DRM
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  • Formaat: 350 pages
  • Sari: Nutraceuticals
  • Ilmumisaeg: 28-Apr-2014
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781040210192

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"Reviewing the health applications of selected metallic elements and the inorganic, organic, and bio-chemistry underlying the formulation of metallonutraceuticals, this comprehensive work provides a detailed description of the fundamentals and end-use applications of a series of metals vital to the metabolic and nutritional activities of human beings. Assuming a basic understanding of the role of metals in human physiology, it addresses various production issues including scaling up, processing, and automation from different scientific perspectives, as well as FDA regulations, institutional regulations, and ethics for industrial operations and corporate transactions"--Provided by publisher.

Contributors from pharmacy, chemistry, and biotechnology explore the role of metals in the borderlands between food and drugs. Their topics include roles of metals in metabolism, the ethnopharmacology and ethnomedicine of metals, therapeutic applications of nanometals, metallo-nano-therapeutics for neurodegenerative diseases, nanometals and complexes in cancer diagnosis and therapy, the relevance of metalloenzymes in biological systems and potential applications, and gold nanoparticles as a promising nanometallic drug delivery system with many therapeutic applications. Annotation ©2014 Ringgold, Inc., Portland, OR (protoview.com)

The nutritional and medicinal value of metals, such as zinc, calcium, and iron, has been known in traditional medicine for a long time. Other metals, such as silver and gold, may also have therapeutic and health benefits. Ancient medicines have long incorporated their use in the treatment of diseases, and they have also more recently been explored for treatment in allopathic medicine, birthing the concept of metallonutraceuticals. The challenge of using metals in the human body is to find forms that are safe and effective.

Handbook of Metallonutraceuticals presents basic concepts related to the nutritional and therapeutic use of metals, product development strategies, and some ideas ready to be applied for condition-specific metallonutraceuticals. The book begins with an overview of the nutraceuticals field and the need for metallonutraceuticals. It considers the roles of various metals in metabolism, reviews the ethnopharmacology and ethnomedicine of metals, and covers the characterization and possible properties of metallonutraceuticals. It also examines bioavailability and drug interactions, and therapeutic applications of nanometals including use as imaging agents, in cancer diagnosis and treatment, as antibacterials and antivirals, in ocular disease, and in neurodegenerative diseases.

The book explores the use of metals in traditional Chinese medicine, potential applications for metalloenzymes, the use of nanosilver in nutraceuticals, and the potential of gold nanoparticles as a drug delivery system. In addition, it addresses intellectual property rights and regulatory considerations regarding metallonutraceuticals. Using an interdisciplinary approach, this user-friendly text provides a knowledge base and inspiration for new research in this exciting field.

Series Preface ix
Foreword xi
Preface xiii
Editors xv
Contributors xvii
1 Concept, Definition, and Need for Metallonutraceuticals
1(14)
Jayant Lokhande
Yashwant Pathak
2 Roles of Metals in Metabolism
15(18)
Jatin Shah
Jayant Lokhande
3 Ethnopharmacology and Ethnomedicine of Metals
33(62)
Jayant Lokhande
Shriniwas Samant
Ganesh Shinde
Yashwant Pathak
4 Characterization of Metallonutraceuticals
95(28)
Jayant Lokhande
Yashwant Pathak
5 Characterization, Bioavailability, and Drug Interactions of Metallonutraceuticals
123(12)
Charles Preuss
6 Therapeutic Applications of Nanometals
135(26)
Amy Broadwater
Bhaskar Mazumder
Yashwant Pathak
7 Metallonanotherapeutics for Neurodegenerative Diseases
161(24)
Komal Vig
Shivani Soni
8 Nanometals and Complexes in Cancer Diagnosis and Therapy
185(40)
Sajid Bashir
Srinath Palakurthi
Hong-Cai Zhou
Jingbo Liu
9 Application of Metals in Traditional Chinese Medicine
225(18)
Bhaskar Mazumder
Shufeng Zhou
Jiayou Wang
Yashwant Pathak
10 Metalloenzymes: Relevance in Biological Systems and Potential Applications
243(20)
Ravi Ramesh Pathak
11 Application of Nanosilver in Nutraceuticals
263(18)
Pranab Jyoti Das
Bhaskar Mazumder
Charles Preuss
12 Regulatory Pathways and Intellectual Property Rights for Metallonutraceuticals
281(10)
Vishal Kataria
Jayant Lokhande
Vrinda Vedi
Yashwant Pathak
13 Gold Nanoparticles: A Promising Nanometallic Drug Delivery System with Many Therapeutic Applications
291(30)
Anastasia Groshev
Danielle Dantuma
Vaibhav Alandikar
Samuel Rapaka
Yashwant Pathak
Vijaykumar Sutariya
Index 321
Yashwant V. Pathak, Ph.D., is currently the associate dean for faculty affairs at the newly launched College of Pharmacy, University of South Florida, Tampa. With extensive experience in academia and industry, Dr. Pathak has over 120 publications, research papers, abstracts, book chapters, and reviews to his credit. He has also coedited six books on nanotechnology and drug delivery systems, four books on nutraceuticals, and several books on cultural studies. Dr. Pathak is the holder of one patent.

Jayant Lokhande, M.D., is an expert in botanical drug product (BDP) and biotechnology business management with integrated economics and regulatory aspects. He has worked for several nutraceuticals companies in the United States and India and has formulated successful strategies for marketing nutraceuticals worldwide. He has significant clinical experience in botanical drugs and the application of nutraceuticals in chronic diseases. He recently started his own company Indus Inc and Indus Extracts in the United States, for which his responsibilities include business analysis, product development, and technical marketing and sales.