This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, and looking ahead to future prospects.
This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine.
- The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine
- Edited by a leader in the field, with contributions from a team of experienced medical physicists
- Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history
This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine.
| Preface |
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| Editor |
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| Contributors |
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Chapter 1 The History of Nuclear Medicine |
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1 | (14) |
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Chapter 2 Basic Atomic and Nuclear Physics |
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15 | (24) |
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Chapter 3 Basics of Radiation Interactions in Matter |
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39 | (30) |
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Chapter 4 Radionuclide Production |
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69 | (20) |
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89 | (18) |
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Chapter 6 Scintillation Detectors |
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107 | (22) |
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Chapter 7 Semiconductor Detectors |
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129 | (16) |
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Chapter 8 Gamma Spectrometry |
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145 | (30) |
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Chapter 9 Properties of the Digital Image |
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175 | (22) |
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Katarina Sjogreen Gleisner |
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Chapter 10 Image Processing |
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197 | (24) |
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Chapter 11 Machine Learning |
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221 | (16) |
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Chapter 12 Image File Structures in Nuclear Medicine |
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237 | (14) |
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Chapter 13 The Scintillation Camera |
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251 | (14) |
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Chapter 14 Collimators for Gamma Ray Imaging |
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265 | (14) |
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Chapter 15 Image Acquisition Protocols |
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279 | (18) |
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Chapter 16 Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging |
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297 | (18) |
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Chapter 17 Dedicated Tomographic Single Photon Systems |
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315 | (18) |
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333 | (10) |
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Chapter 19 Dead-time Effects in Nuclear Medicine Imaging Studies |
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343 | (12) |
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Chapter 20 Principles of Iterative Reconstruction for Emission Tomography |
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355 | (34) |
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Chapter 21 PET-CT Systems |
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389 | (8) |
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Chapter 22 Clinical Molecular PET/MRI Hybrid Imaging |
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397 | (30) |
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Chapter 23 Quality Assurance of Nuclear Medicine Systems |
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427 | (28) |
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Chapter 24 Calibration and Traceability |
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455 | (8) |
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Chapter 25 Activity Quantification from Planar Images |
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463 | (16) |
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Katarina Sjogreen Gleisner |
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Chapter 26 Quantification in Emission Tomography |
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479 | (20) |
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Chapter 27 Multicentre Studies: Hardware and Software Requirements |
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499 | (16) |
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Chapter 28 Preclinical Molecular Imaging Systems |
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515 | (18) |
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Chapter 29 Monte Carlo Simulation of Nuclear Medicine Imaging Systems |
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533 | (30) |
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Chapter 30 Beta and Alpha Particle Autoradiography |
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563 | (26) |
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Chapter 31 Principles behind Computed Tomography (CT) |
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589 | (16) |
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Chapter 32 Principles behind Magnetic Resonance Imaging (MRI) |
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Michael Ljungberg is a Professor at Medical Radiation Physics, Lund, Lund University, Sweden. He started his research in the Monte Carlo field in 1983 through a project involving a simulation of whole-body counters but later changed the focus to more general applications in nuclear medicine imaging and Single Photon Emission Computed Tomography (SPECT). As a parallel to his development of the Monte Carlo code SIMIND, he started working in 1985 with quantitative SPECT and problems related to attenuation and scatter. After earning his PhD in 1990, he received a research assistant position that allowed him to continue developing SIMIND for quantitative SPECT applications and established successful collaborations with international research groups. At this time, the SIMIND program also became used worldwide. Dr. Ljungberg became an associate professor in 1994 and in 2005, after working clinically as a nuclear medicine medical physicist, received a full professorship in the Science Faculty at Lund University. He became head of the Department of Medical Radiation Physics in 2013 and a full professor in the Medical Faculty in 2015.
Besides the development of SIMIND to include a new camera system with CZT detectors, his research includes an extensive project in oncological nuclear medicine and, with colleagues, he developed dosimetry methods based on quantitative SPECT, Monte-Carlo absorbed dose calculations, and methods for accurate 3D dose planning for internal radionuclide therapy. In recent years, his work has focused on implementing Monte-Carlo based image reconstruction in SIMIND. He is also involved in the undergraduate education of medical physicists and biomedical engineers and is supervising MSC and PhD students. In 2012, Professor Ljungberg became a member of the European Association of Nuclear Medicines task group on dosimetry and served in that group for six years. He has published over a hundred original papers, 18 conference proceedings, 18 books and book chapters and 14 peer- reviewed papers.
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