Hansens disease (leprosy) is endemic in more than 100 countries worldwide, with over 200,000 new diagnoses each year and more than 4 million people living with some form of HD-related impairment. The World Health Organizations Global Leprosy Strategy timeline for Hansens disease elimination indicates that it will be encountered in clinical practice in endemic countries for at least another decade. Increasing north-to-south migration, global travel and overseas medical work mean that physicians in non-endemic countries will also encounter patients with Hansens disease, which can affect people for many years before diagnosis and after treatment. For busy clinicians, it represents a challenge, in terms of disease learning and updating knowledge and skills.
This book provides a concise, up-to-date, and comprehensive source of information on Hansens disease clinical practice. It covers essential topics on all clinical aspects, complemented by history, epidemiology, paleopathology, and the social impact of the disease. Edited and written by contributors with decades of experience, its divided into twenty-six chapters clarifying the genetics and neurological manifestations, physical disabilities and its prevention; oral, ophthalmological, and bone changes, among others.
For the primary audience of practicing physicians, it is an affordable point of reference, whilst also being suitable for student and trainee doctors. Its also accessible to general practitioners and specialists in dermatology, neurology, pediatrics, infectious disease, family and community medicine, and orthopedics, as well as to non-specialists and other healthcare professionals.
Chapter 1: Introduction to Hansens disease.- Chapter 2: The journey to
a scientific understanding of leprosy: a brief outline.- Chapter 3: The
origin, evolution and history of leprosy through a paleopathological
lens.- Chapter 4: Hansens disease and Human Rights.- Chapter 5: Leprosy
agents and principal methods of detection, identification and
characterization of the leprosy agents.- Chapter 6: Epidemiology of Hansens
Disease.- Chapter 7: Hansens Disease and One Health.- Chapter 8: Metabolic,
genetic and immunological mechanisms in susceptibility to leprosy.- Chapter
9: Clinical aspects and classification of Hansens disease.- Chapter
10: Reaction in Hansens disease.- Chapter 11: Hansens disease in
children.- Chapter 12: Neuropathophysiology in Hansens disease: mechanisms
of nerve injury.- Chapter 13: Neurological manifestations.- Chapter
14: Evaluation, monitoring, and prevention of disabilities in Hansens
disease.- Chapter 15: Ophthalmological alterations in Hansens
disease.- Chapter 16: Ear, nose, throat and mouth alterations in Hansens
disease.- Chapter 17: Osteoarticular alterations in Hansens
disease.- Chapter 18: Diagnostic Imaging in Hansens Disease: Conventional
Radiography, Computed Tomography, Magnetic Resonance Imaging, and Dual-energy
X-ray Absorptiometry.- Chapter 19: Coinfection and immunosuppression in
Hansens disease.- Chapter 20: Differential diagnosis of cutaneous lesions of
Hansens disease.- Chapter 21: Differential diagnoses of the neurological
manifestations of Hansens disease.- Chapter 22: Immune and Chemoprophylaxis
in Hansens disease.- Chapter 23: Psychosocial aspects of Hansens
diseases.- Chapter 24: Peripheral Nerve by Ultrasound in Hansens
Disease.- Chapter 25: Electroneuromyography in Hansens Disease.- Chapter 26:
Treatment of Hansens disease.
EDITOR
Professor Patrícia D. Deps is a physician specializing in dermatology and Hansens disease and Professor at the Department of Social Medicine, from Federal University of Espirito Santo, Vitoria, Brazil. She is member of the following medical societies: Brazilian Society of Dermatology; Brazilian Society of Hansenology; European Academy of Dermatology and Venereology; Sociétè Française de Dermatologie. Dr. Deps holds a Masters degree in Infectious Diseases (UFES, 1998) and a Ph.D. in Dermatology (UNIFESP, 2003). She undertook post-doctoral training in Tropical Dermatology at the London School of Hygiene and Tropical Medicine (2008) and in Medical Anthropology at the Université Versailles Saint-Quintin-en-Yvelines (2018/2019). She is active in the fields of Hansens disease, clinical and tropical dermatology, public health, medical history and ethics, paleopathology, anthropology, and medical education, and teaches medical and postgraduate students at UFES. Professor Deps has written and published peer-reviewed scientific articles, a bilingual book The day I changed my name Hansens disease and stigma (Édition de Boccard, Paris, 2019), and literary works. She is Vice-President for the Americas in the International Leprosy Association (2023-2026), member of the Scientific Review Committee of the Leprosy Research Initiative (2020-2024), member of the World Health Organization, Technical Advisory Group-Leprosy (2022-2025), Global Leprosy Programme, and Technical Adviser.
ASSOCIATE EDITORS
Professor Marcos Cesar Florian is a physician specializing in dermatology and Hansens disease. He has been member of the Brazilian Society of Dermatology since 1995 and of the Brazilian Society of Hansenology since 2001. Dr. Marcos holds Masters and PhD in Dermatology (Federal University of São Paulo). He is Affiliate Professor of Department of Dermatology at Federal University of Sao Paulo and Professor of Medicine at University Nove de Julho. He is member of the Research Ethics Committee of the Faculty of Pharmaceutical Sciences at University of São Paulo. Professor Florian is active in the following areas: Hansens disease, skin diseases and immunodepression, clinical and tropical dermatology, diseases in indigenous populations, dermatology in primary care, and medical education. He has published several peer-reviewed scientific articles and the book Dermatological Atlas - Indigenous People (Springer, 2017).
Professor Marcos da Cunha Lopes Virmond is a physician specializing in reconstructive plastic surgery and Hansens disease, and teaches medical and postgraduate students at FOB-USP. Heis former President of the Brazilian Society of Hansenology and of the International Leprosy Association, and former director of the Instituto Lauro de Souza Lima (ILSL). Professor Virmond holds a PhD in Surgery (State University of Sao Paulo) and is member of the Brazilian Society of Plastic Surgery. He has experience in the field of Hansenology, working mainly in the areas of rehabilitation, public health, restorative surgery, epidemiology, and disabilities. He is former editor of the journals Salusvita and Mimesis. Dr. Virmond also holds a PhD in music and teaches and researches musicology.
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