An examination of research studies on helicobacter infection, which describes new data on pathogenetic and pathophysiological mechanisms and new methods that are proving to be more successful at identifying the infection.
In the rapidly evolving field of Helicobacter infection newdata on pathogenetic and pathophysiological mechanism haveappeared. New methods which will be more sensitive andspecific in the diagnosis of the infection are beingdeveloped and in this proceedings the first attempt usingPCR technology is published. From the clinical point ofview, a challenging aspect that needs clarification, is theobservation which suggests an appearance of a correlationbetween the presence of the bacteria and abdominal pain andother symptoms in children whereas in old age no suchcorrelation is evident. The relationship of H. pylori andgastric cancer is studied with histopathological data andepidemiological approaches. On the treatment side schemesusing short courses and new antibiotic combinations arebeing investigated and preliminary data are reported.
I. Microbiology.- Helicobacter pylori Detection by Polymerase Chain
Reaction of the Gene Encoding 16S Ribosomal RNA in Fresh and
Paraffin-Embedded Material.- Polymerase Chain Reaction for Helicobacter
pylori.- Helicobacter pylori Strains from Duodenal Ulcer Patients Differ at
the Genomic Level from Those Patients with Simple Gastritis.- Perspectives on
the Microbiology of Helicobacter pylori.- II Epidemiology.- A Descriptive
Study of the Characteristics of People with Helicobacter pylori Infection.-
High Prevalence of Helicobacter pylori-Induced Gastritis in China: Results of
a Screening Study in 194 Adolescents.- Seroepidemiology of Helicobacter
pylori Infection in Vegans and Meat Eaters.- Seroepidemiology of Helicobacter
pylori Infection in the Armed Forces.- Helicobacter pylori Infection Clusters
in Families of Healthy Individuals.- Reinfection with Helicobacter pylori Due
to Intrafamilial Clustering of the Organism.- Epidemiology: Summary of
Workshop and Future Prospects.- III. Pathophysiology.- Superficial Components
from Helicobacter pylori That Are Adherent to Epithelial Cells.- Bismuth
Bioavailability from 205Bi-Labelled Bismuth Compounds Used in Suppression of
Helicobacter pylori and Treatment of Peptic Ulcer.- Optical and Electronic
Findings in Helicobacter pylori Infection of Antral Mucosa.- Bacteria and
Gastrin Release.- Helicobacter pylori, Gastritis, Duodenal Ulcer, and Gastric
Histamine Content.- Detection of Phospholipases and Cytotoxic Activities of
Helicobacter pylori.- IV. Pathology.- Antral Follicular Gastritis Is
Characteristic of Helicobacter pylori Infection.- Defining the Role of
Helicobacter pylori in Relationship to Relapse of Duodenal Ulcer.- Gastritis
and Helicobacter pylori Prevalence in Patients with Heterotopic Gastric
Mucosa or Gastric Metaplasia in the Duodenum.- Evolution of Gastritis After
Helicobacter pylori Eradication.- Histological Improvements in Gastritis
After Eradication of Helicobacter pylori Infection.- Helicobacter pylori in
Subtotal Gastrectomies.- Helicobacter pylori and Duodenal Ulcer.-
Helicobacter pylori and the Oesophagus.- Gastritis: A Short Appraisal of
Classification and the Sydney System.- V. Immunology.- Stress Proteins and
Local Immune Response in Helicobacter pylori-Associated Chronic Gastritis.-
Local and Systemic Antibody Responses During Helicobacter pylori Infections.-
Local Immunoglobulin A Subclass Alteration in the Gastric Mucosa of
Helicobacter pylori-Infected Patients.- Antibodies Against Helicobacter
pylori as an Indicator of Antrum Gastritis.- Antibodies to Vacuolating Toxin
of Helicobacter pylori in Dyspeptic Patients.- Cytokines and Mucosal Immune
Responses to Helicobacter pylori.- Immunological Aspects of Helicobacter
pylori Infection.- VI. Diagnostic Progress.- Usefulness of Two Enzyme-Linked
Immunosorbent Assay Systems for the Diagnosis of Helicobacter
pylori-Associated Gastritis.- VII Helicobacter pylori and Non-ulcer
Dyspepsia.- Helicobacter pylori Infection in Gastroesophageal Reflux
Disease.- Computerised History Taking for the Assessment of Helicobacter
pylori in Non-ulcer Dyspepsia: The Quest for the Clinical Syndrome.- VIII.
Helicobacter pylori and Malignant Growth.- Prevalence of Helicobacter pylori
in Patients with Malignant Growth of Gastric Mucosa.- A Role for Helicobacter
pylori in Gastric Carcinoma?.- Increased Incidence of Helicobacter pylori in
Gastric Cancer, as Shown by the Rapid Urease Test.- Evaluation of the
Presence and Amount of Helicobacter pylori in Early Gastric Cancer.-
Helicobacter pylori prevalence in Patients with Severe Dysplasia of Gastric
Epithelium and Associated Pathology.- Gastric Cancer and Helicobacter
pylori.- Role of Helicobacter pylori in Gastric Carcinogenesis: Future
Prospects.- IX. Helicobacter pylori in Children.- Epidemiology of
Helicobacter pylori Infection in Pediatrics: A Serologic Study.- Prevalence
of Antibody of Helicobacter pylori in Children in Northern Nigeria.-
Prevalence of Immunoglobulin G Antibodies to Helicobacter pylori in Mothers
of Newborns with Upper Gastrointestinal Bleeding.- Helicobacter pylori
Infection in Children.- Histological and Serological Examination of
Helicobacter pylori in Estonian Children with Abdominal Complaints.-
Helicobacter pylori in Children with Recurrent Abdominal Pain and Other
Conditions.- Helicobacter pylori-Associated Gastritis in Children.-
Helicobacter pylori Gastritis in Children: Wide Spectrum of Symptoms.-
Childhood Peptic Ulcer Can Be Cured by Eradicating Helicobacter pylori.-
Helicobacter pylori Infection and Gastroduodenal Pathology in Children.- X.
Treatment.- Solubility Characteristics of Different Bismuth Salts in Gastric
Juice.- Assessment of Susceptibility of Helicobacter pylori to Tinidazole,
Amoxicillin and Tetracycline Among 555 Patients.- In Vivo Acquired Resistance
to Fluorquinolones in Helicobacter pylori During Therapy with Ciprofloxacin
Alone or Ciprofloxacin plus Amoxicillin Clavulanate.- Treatment of
Helicobacter pylori-Positive Lesions: 13C-Urea Breath Test Monitoring and
Morphology.- Colloidal Bismuth Subcitrate Plus Amoxicillin Versus Colloidal
Bismuth Subcitrate plus Ofloxacin in the Treatment of Chronic Antral
Gastritis Positive for Helicobacter pylori.- Factors Affecting Eradication of
Helicobacter pylori with Triple Therapy.- Comparison of Three Triple
Therapies in the Eradication of Helicobacter pylori.-
Ciprofloxacin-Omeprazole Treatment for Eradication of Helicobacter pylori.-
Amoxicillin-Omeprazole Treatment for Eradication of Helicobacter pylori.-
Eradication of Helicobacter pylori Cures Duodenal Ulcer Disease.- Two-Month
Assessment of Duodenal Ulcer Healing and Helicobacter pylori Eradication
Rates in Patients Treated for One Month with Omeprazole Alone or Combined
with Antibiotics.- Helicobacter pylori and Healing of Refractory Duodenal
Ulcer: Preliminary Results of a Randomised Trial.- Treatment with Amoxicillin
and Colloidal Bismuth Subcitrate in Children with Helicobacter
pylori-Associated Peptic Disease.- Helicobacter pylori and Duodenal Ulcer
Relapse: Effect of Bismuth-Free Short-Term Triple Therapy.- Bismuth
Subnitrate in Comparison to Ranitidine in Patients with Non-ulcer Dyspepsia:
A Randomized Controlled Trial.- Colloidal Bismuth Subcitrate Versus
Amoxicillin in the Treatment of Helicobacter pylori-Associated Type B
Gastritis.- Response of Helicobacter pylori-Associated Gastritis to Colloidal
Bismuth Subcitrate Versus Ranitidine in Patients with Duodenal Ulcer: A
Detailed Histological Assessment.- Eradication of Helicobacter pylori:
Summary of Workshop.- Treatment of Helicobacter pylori Infection: Challenges
and Future Prospects.