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E-raamat: Imaging in Cellular and Tissue Engineering

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  • Formaat: 298 pages
  • Ilmumisaeg: 16-May-2013
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781439848043
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  • Formaat: 298 pages
  • Ilmumisaeg: 16-May-2013
  • Kirjastus: CRC Press Inc
  • Keel: eng
  • ISBN-13: 9781439848043
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"This book covers the full range of available imaging modalities and optical methods used to help evaluate material and biological behavior. It also highlights a wide range of optical and biological applications. Each chapter in the text describes a specific application and discusses relevant instrumentation, governing physical principles, data processing procedures, as well as advantages and disadvantages of each modality. Following a broad introduction to key topics, the main chapters are divided between in vitro and in vivo applications. The final section focuses on methods for data processing and analysis"--Provided by publisher.

Physicists, electronic and biochemical engineers, and other contributors describe how imaging is used in specific application of cellular and tissue engineering. Their topics include confocal microscopy for high-content cellular screening, magnetic resonance imaging to monitor implanted constructs, applying imaging technologies to stem-cell tracking in vivo, imaging therapeutic processes in animals using optical reporter genes, and image analysis for cellular and tissue engineering. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)

Details on specific imaging modalities for different cellular and tissue engineering applications are scattered throughout articles and chapters in the literature. Gathering this information into a single reference, Imaging in Cellular and Tissue Engineering presents both the fundamentals and state of the art in imaging methods, approaches, and applications in regenerative medicine.

The book underscores the broadening scope of imaging applications in cellular and tissue engineering. It covers a wide range of optical and biological applications, including the repair or replacement of whole tissues (such as bone, cartilage, blood vessels, and bladder) and more novel artificially created support systems (such as artificial pancreas and bioartificial liver). Each chapter describes a particular application, relevant optical instrumentation, physical principles governing the imaging method, and strengths and weaknesses of the technique. The book also presents current and emerging data processing procedures.

As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Abbreviations ix
Series Preface xiii
Preface xv
Acknowledgments xvii
Editors xix
Contributors xxi
PART I Overview
1 Introduction to Cellular and Tissue Engineering
3(8)
Hanry Yu
Abhishek Ananthanarayanan
PART II In Vitro Applications
2 Confocal Microscopy for Cellular Imaging: High-Content Screening
11(14)
Baixue Zheng
Abhishek Ananthanarayanan
3 Use of Multiphoton Microscopy for Tissue Engineering Applications
25(8)
Wei-Liang Chen
Hsuan-Shu Lee
Chen-Yuan Dong
4 Two-Photon Microscopy for Surface Mapping and Organ Characterization
33(26)
Anju Mythreyi Raja
5 Atomic Force Microscopy for Cell and Tissue Niches
59(28)
Wanxin Sun
PART III In Vivo Applications
6 Magnetic Resonance Imaging to Monitor Implanted Constructs
87(36)
Nicholas E. Simpson
Athanassios Sambanis
7 Application of Imaging Technologies to Stem-Cell Tracking In Vivo
123(16)
Sheng-Xiang Xie
Kishore Kumar Bhakoo
8 Computer Tomography and Micro-CT for Tissue Engineering Applications
139(16)
Zhang Zhiyong
Jerry K. Y. Chan
Teoh Swee Hin
9 Intravascular Optical Coherence Tomography
155(18)
Liu Linbo
Atsushi Tanaka
10 Imaging of Therapeutic Processes in Animals Using Optical Reporter Genes
173(18)
Ying Zhao
Jiakai Lin
Shu Wang
11 Imaging in Metabolic Medicine
191(22)
Jinling Lu
Kishore Kumar Bhakoo
Kai-Hsiang Chuang
George K. Radda
Philip W. Kuchel
Weiping Han
12 High-Resolution X-Ray Cone-Beam Microtomography
213(10)
Xiaochun Xu
Ping-Chin Cheng
PART IV Data Analysis
13 Image Analysis for Cellular and Tissue Engineering
223(24)
Shuoyu Xu
Piyushkumar A. Mundra
Huipeng Li
Shiwen Zhu
Roy E. Welsch
Jagath C. Rajapakse
Index 247
Hanry Yu is a professor in the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore. He is also the group leader in the Institute of Bioengineering and Nanotechnology (A*STAR), principal investigator in the Research Centre of Excellence in Mechanobiology, and visiting associate professor in the Department of Biological Engineering at the Massachusetts Institute of Technology. His research activities over the past decade involve interfacing biomaterials with tissue engineering. Dr. Yu earned a PhD in cell biology from Duke University.





Nur Aida Abdul Rahim was a postdoctoral researcher in the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore. Her research interests range from imaging intracellular fluorescent fusion protein interaction kinetics to stem cell migration and differentiation in microfluidic devices. She earned a PhD in mechanical engineering from the Massachusetts Institute of Technology.