E-raamat: Imaging Mass Spectrometry: Methods and Protocols

Edited by Malcolm R Clench, Edited by Laura M Cole

Formaat: PDF+DRM
Sari: Methods in Molecular Biology 2688
Ilmumisaeg: 06-Jul-2023
Kirjastus: Springer-Verlag New York Inc.
Keel: eng
ISBN-13: 9781071633199

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Formaat: PDF+DRM
Sari: Methods in Molecular Biology 2688
Ilmumisaeg: 06-Jul-2023
Kirjastus: Springer-Verlag New York Inc.
Keel: eng
ISBN-13: 9781071633199

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This second edition details new and updated chapters on key methodologies and breakthroughs in the mass spectrometry imaging (MSI) field. Chapters guide readers through nano-Desorption Electrospray Ionisation (nDESI), Matrix Assisted Laser Desorption Ionisation-2 (MALDI-2), Laser Ablation - Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) ,Imaging Mass Cytometry (IMC) with a variety of diverse samples including eye tissue, crop analysis, 3D cell culture models, and counterfeit goods analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Imaging Mass Spectrometry: Methods and Protocols, Second Edition aims to be a useful and practical guide to new researchersand experts looking to expand their knowledge.

MALDI and Trace Metal Analysis in Age Related Macular
Degeneration.- HistoSnap: a novel software tool to extract m/z-specific
images from large MSHC datasets.- Spatially resolved quantitation of drug in
skin equivalents using Mass Spectrometry Imaging (MSI).- Update DESI Mass
Spectrometry Imaging (MSI).- Update Liquid Extraction Surface Analysis Mass
Spectrometry Imaging of Denatured Intact Proteins.- MALDI MS imaging of
cucumbers.- The adaptation of the QV600 LLI Milli-Fluidics System to house ex
vivo gastrointestinal tissue suitable for drug absorption and permeation
studies, utilising MALDI-MSI and LC-MS/MS.- Ambient Mass Spectrometry Imaging
by Water-Assisted Laser Desorption Ionization For Ex Vivo And In Vivo
Applications.- Cytological cytospin preparation for the spatial proteomics
analysis of thyroid nodules using MALDI-MSI.- Matrix effects free imaging of
thin tissue sections using pneumatically assisted nano-DESI MSI.- Laser
Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant
Materials.- Sample Preparation for Metabolite Detection in Mass Spectrometry
Imaging.- Multimodal Mass Spectrometry Imaging of an Aggregated 3D Cell
Culture Model.- Visualization of Small Intact Proteins in Breast Cancer FFPE
tissue.- Negative Ion-mode N-glycan Mass Spectrometry Imaging by
MALDI-2-TOF-MS.- MS1-based data analysis approaches for FFPE tissue imaging
of endogenous peptide ions by mass spectrometry histochemistry (MSHC).- Mass
Spectrometry Imaging: The Next Five Years.

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