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E-raamat: Immunology E-Book: Immunology E-Book

Edited by (Professor of Biology, Department of Life Sciences, The Open University, Milton Keynes, UK), Edited by (Professor of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, ), Edited by
  • Formaat: PDF+DRM
  • Ilmumisaeg: 19-Feb-2020
  • Kirjastus: Elsevier Health Sciences
  • Keel: eng
  • ISBN-13: 9780702078460
  • Formaat - PDF+DRM
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  • Formaat: PDF+DRM
  • Ilmumisaeg: 19-Feb-2020
  • Kirjastus: Elsevier Health Sciences
  • Keel: eng
  • ISBN-13: 9780702078460

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Covering all the basic and clinical concepts you need to know for your coursework and USMLEs, Immunology, 9th Edition, offers a well-illustrated, carefully structured approach to this complex and fast-changing field. Carefully edited and authored by experts in both teaching and research, it provides cutting-edge, consistent coverage that links the laboratory and clinical practice. A user-friendly, color-coded format, including key concept boxes, explanatory diagrams, and nearly 200 photos to help you visually grasp and retain challenging concepts.

  • Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context.
  • Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more.
  • Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology.
  • Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.
  • Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams - plus more learning opportunities online, including USMLE-style questions and clinical cases.
  • Enhanced eBook version included with purchase.
  • Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. It also features full color 3-D animations to deliver a dynamic visual overview of immunological concepts.

      Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more.

      Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.

      Preface to the 9th edition vii
      Contributors ix
      SECTION 1 The Immune System and Innate Immunity
      1 Introduction to the Immune System
      1(13)
      David Male
      2 Cells, Tissues and Organs of the Immune System
      14(32)
      Peter Maldwyn Lydyard
      Nina Porakishvili
      3 Mechanisms of Innate Immunity
      46(15)
      David Male
      4 Complement
      61(18)
      Bryan Paul Morgan
      5 Mononuclear Phagocytes in Immune Defence
      79(17)
      Luisa Martinez-Pomares
      SECTION 2 Adaptive Immune Responses
      6 T-Cell Receptors and Major Histocompatibility Complex Molecules
      96(13)
      Victoria Male
      7 Antigen Presentation
      109(13)
      Victoria Male
      8 Cell-Mediated Cytotoxicity
      122(11)
      Victoria Male
      9 B-Cell Development and the Antibody Response
      133(15)
      David Male
      10 Antibodies
      148(15)
      Roy Jefferis
      Gestur Vidarsson
      Theo Rispens
      11 Immunological Tolerance
      163(15)
      David Male
      Thomas Kamradt
      12 Regulation of the Immune Response
      178(14)
      David Bending
      13 Immune Responses in Tissues
      192(10)
      David Male
      SECTION 3 Defence Against Infectious Agents
      14 Immunity to Viruses
      202(12)
      Persephone Borrow
      15 Immunity to Bacteria and Fungi
      214(19)
      Gregory J. Bancroft
      16 Immunity to Protozoa and Worms
      233(17)
      Richard John Pleass
      17 Vaccination
      250(13)
      Colin Casimir
      SECTION 4 Immunodeficiency
      18 Primary Immunodeficiencies
      263(13)
      Luigi D. Notarangelo
      19 AIDS, Secondary Immunodeficiency and Immunosuppression
      276(11)
      Yasmin Khan
      Daniel Dulek
      SECTION 5 Immune Responses Against Tissues
      20 Autoimmunity and Autoimmune Disease
      287(18)
      David Isenberg
      Arti Mahto
      21 Transplantation and Rejection
      305(14)
      Andrew George
      22 Immunity to Cancers
      319(13)
      Pramod K. Srivastava
      Hakimeh Ebrahimi-Nik
      SECTION 6 Hypersensitivity
      23 Immediate Hypersensitivity (Type I)
      332(20)
      Thomas A. E. Platts-Mills
      24 Hypersensitivity (Type II)
      352(10)
      David Male
      25 Hypersensitivity (Type III)
      362(10)
      David P. D'Cruz
      26 Hypersensitivity (Type IV)
      372(12)
      Daniel Cook
      R. Stokes Peebles Jr.
      Critical thinking: Explanations 384(10)
      Glossary 394(6)
      Index 400
      David Male is Professor of Biology in the Department of Life Sciences at The Open University, Milton Keynes. R. Stokes Peebles is Professor of Medicine in the Division of Allergy, Pulmonary and Critical Care Medicine at Vanderbilt University Medical Center, Nashville, Tennessee.