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E-raamat: Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products

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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 09-Jun-2011
  • Kirjastus: John Wiley & Sons Inc
  • Keel: eng
  • ISBN-13: 9781118025321
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  • Formaat: EPUB+DRM
  • Ilmumisaeg: 09-Jun-2011
  • Kirjastus: John Wiley & Sons Inc
  • Keel: eng
  • ISBN-13: 9781118025321

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An in-depth look at cutting-edge research on the body's innate immune system

Innate immunity is the body's first line of protection against potential microbial, viral, and environmental attacks, and the skin and oral mucosa are two of the most powerful barriers that which we rely on to stay well. The definitive book on the subject, Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products provides a comprehensive overview of these systems, including coverage of antimicrobial peptides and lipids and microbial challenges and stressors that can influence innate immunity.

Designed to help experts and newcomers alike in fields like dermatology, oral pathology, cosmetics, personal care, and pharmaceuticals, the book is filled with suggestions to assist research and development. Looking at the many challenges facing the innate immune system, including the impact of topically applied skin products and medications, Innate Immune System of Skin and Oral Mucosa paves the way for next generation treatment avenues, preventative approaches, and drug development.
Preface ix
Contributors xi
PART I OVERVIEW OF SKIN AND MUCOSAL INNATE IMMUNITY: HISTORY, ETHICS, AND SCIENCE
Chapter 1 Germ Free: Hygiene History and Consuming Antimicrobial and Antiseptic Products
3(40)
Jennifer Tebbe-Grossman
Martha N. Gardner
Chapter 2 Ethical Responsibilities in Formulating, Marketing, and Using Antimicrobial Personal Products
43(16)
Kenneth A. Richman
Chapter 3 Role of Stratum Corneum in Permeability Barrier Function and Antimicrobial Defense
59(16)
Peter M. Elias
PART II ANTIMICROBIAL LIPIDS AND PEPTIDES
Chapter 4 Antimicrobial Lipids of the Skin and Oral Mucosa
75(8)
Kim A. Brogden
David R. Drake
Deborah V. Dawson
Jennifer R. Hill
Carol L. Bratt
Philip W. Wertz
Chapter 5 Resident Microflora and Antimicrobial Peptides of Skin
83(26)
Shamim A. Ansari
Chapter 6 Defensins
109(8)
Neelam Muizzudin
Chapter 7 Antimicrobial Peptides of Skin and Oral Mucosa
117(28)
Whasun O. Chung
Henrik Dommisch
Chapter 8 Vernix Caseosa and Innate Immunity
145(28)
Steven B. Hoath
Vivek Narendran
Marty O. Visscher
PART III HOST CELLULAR COMPONENTS OF INNATE IMMUNITY
Chapter 9 Sentinel Role of Mast Cells in Innate Immunity
173(22)
Zhenping Wang
Anna Di Nardo
Chapter 10 Cellular Immunity of the Skin: Langerhans Cells and Dendritic Cells
195(22)
Karen E. Burke
Niroshana Anandasabapathy
PART IV INNATE IMMUNITY RESPONSE TO STRESS AND AGING
Chapter 11 Changes in Skin Immunity with Age and Disease
217(42)
Barbara Geusens
Ilse Mollet
Chris D. Anderson
Sarah Terras
Michael S. Roberts
Jo Lambert
Chapter 12 Epidermis as a Shield from Radiation and Oxidative Stress
259(16)
Giuseppe Valacchi
Chapter 13 The Impact on the Skin's Innate Immunity by Cosmetic Products Applied to the Skin and Scalp
275(6)
Rudranath Persaud
Thomas Re
Chapter 14 UV-Induced Immunosuppression of Skin
281(26)
Roger L. McMullen
PART V INNATE IMMUNITY MICROBIAL CHALLENGES
Chapter 15 Deranged Antimicrobial Barrier in Atopic Dermatitis: Roles of Sphingosine, Hexadecenoic Acid, and Beta-Defensine-2
307(18)
Gengi Imokawa
Chapter 16 Resident Microflora of the Skin and Oral Mucosa
325(8)
David R. Drake
Chapter 17 Corynebacterium Species and their Role in the Generation of Human Malodor
333(18)
Carol L. Bratt
Nava Dayan
Index 351
Nava Dayan PhD, is the R&D Director at Lipo Chemicals Inc. and an Associate Adjunct Professor in the Ernest Mario School of Pharmacy at Rutgers University. During her twenty four years of experience she has specialized in a variety of areas related to skin treatment, especially in the research and understanding of the interaction between topically applied compounds and the skin. Dr. Dayan has received numerous awards for excellence for various papers she has authored. She is the author and coauthor of more than a hundred and fifty publications, including book chapters, and has been granted eight patents. She is also the editor of three books, including Formulating, Packaging, and Marketing of Natural Cosmetic Products (Wiley). Philip W. Wertz PhD, is a Professor in the Department of Oral Pathology, Radiology, and Medicine at the University of Iowa College of Dentistry and in The Dows Institute for Dental Research. He is currently on the Editorial Advisory Board of the International Journal of Cosmetic Science and the Editorial Board of the TransDermal and Journal of Lipids.