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E-raamat: Lead Compounds from Medicinal Plants for the Treatment of Cancer

(Ethnopharmacologist and Associate Professor, School of Pharmacy, University of Nottingham, Malaysia Campus)
  • Formaat: EPUB+DRM
  • Ilmumisaeg: 23-Nov-2012
  • Kirjastus: Academic Press Inc
  • Keel: eng
  • ISBN-13: 9780123983824
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Lead Compounds from Medicinal Plants for the Treatment of CancerSuurem pilt
  • Formaat: EPUB+DRM
  • Ilmumisaeg: 23-Nov-2012
  • Kirjastus: Academic Press Inc
  • Keel: eng
  • ISBN-13: 9780123983824
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Wiart, an ethnopharmacologist at the U. of Nottingham, UK, itemizes medical plants from Europe, Asia, North America, South America, and Africa that have lead compounds with the potential to treat cancer, including alkaloids, terpenes, and phenolics. Each plant description has information on its synonym, family, common names, habitat, medicinal uses, chemistry, phytopharmacology, proposed research, and rationales describing anticancer activity in vitro, anticancer mechanisms, antitumor activity in the animal model, the active component, and its derivative. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)

Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today’s most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development.

  • Provides a compilation of hundreds of medicinal plants from Europe, Asia, North and South America and Africa that contain prominent lead candidates for anti-cancer drug discovery
  • Contains primary source references and hundreds of the most relevant citations from the current literature for additional research
  • Offers cancer researchers and pharmaceutical scientists valuable tools such as chemical structures and promising pharmacological data to help them select the novel lead compounds that will best aid drug discovery.

Arvustused

"Wiart, an ethnopharmacologist at the U. of Nottingham, UK, itemizes medical plants from Europe, Asia, North America, South America, and Africa that have lead compounds with the potential to treat cancer, including alkaloids, terpenes, and phenolics." --Reference and Research Book News, August 2013

Muu info

Contains hundreds of pharmaceutical leads from medicinal plants with the therapeutic potential to help treat cancer
Foreword ix
Gordon M. Cragg
Foreword xiii
David J. Newman
Preface xv
About the Author xvii
Chapter 1 Alkaloids
1(96)
Introduction
1(1)
Topic 1.1 Amide Alkaloids
2(14)
1.1.1 Piper Boehmeriifolium (Miq.) Wall. ex C. DC
2(3)
1.1.2 Piper Caninum Blume
5(3)
1.1.3 Piper Chaba Hunter
8(2)
1.1.4 Piper Longum L.
10(3)
References
13(3)
Topic 1.2 Indole Alkaloids and Derivatives
16(19)
1.2.1 Alstonia Yunnanensis Diels
16(3)
1.2.2 Clausena Harmandiana (Pierre) Guillaumin
19(2)
1.2.3 Melodinus Henryi Craib
21(3)
1.2.4 Nauclea Orientalis Willd
24(3)
1.2.5 Winchia Calophylla A. DC
27(3)
References
30(5)
Topic 1.3 Isoquinoline Alkaloids and Derivatives
35(32)
1.3.1 Alangium Salviifolium (L. f.) Wangerin
35(3)
1.3.2 Aristolochia Cucurbitifolia Hayata
38(2)
1.3.3 Aristolochia Manshuriensis Kom
40(3)
1.3.4 Cocculus Trilobus (Thunb.) DC
43(3)
1.3.5 Corydalis Ternata (Nakai) Nakai
46(2)
1.3.6 Cyclea racemosa Oliv
48(3)
1.3.7 Goniothalamus Amuyon (Blco.) Merr
51(4)
1.3.8 Macleaya Microcarpa (Maxim.) Fedde
55(4)
References
59(8)
Topic 1.4 Terpenoid Alkaloids
67(14)
1.4.1 Daphniphyllum Glaucescens Blume
67(3)
1.4.2 Nuphar Pumila (Timm) DC
70(2)
1.4.3 Pachysandra Terminalis Siebold & Zucc
72(6)
References
78(3)
Topic 1.5 Other Alkaloids
81(16)
1.5.1 Dysoxylum Acutangulum Miq
81(3)
1.5.2 Ficus Septica Burm.f
84(8)
References
92(5)
Chapter 2 Terpenes
97(170)
Introduction
97(2)
Topic 2.1 Sesquiterpenes
99(29)
2.1.1 Atractylodes Macrocephala Koidz
99(4)
2.1.2 Curcuma Wenyujin Y.H. Chen & C. Ling
103(4)
2.1.3 Duhaldea Cappa (Buch.Ham. ex D. Don) Pruski & Anderb
107(3)
2.1.4 Ixeris Chinensis (Thunb.) Kitag
110(8)
2.1.5 Parasenecio Delphiniphyllus (H. Lev.) Y.L. Chen
118(4)
References
122(6)
Topic 2.2 Diterpenes
128(19)
2.2.1 Clerodendrum Kaichianum P.S. Hsu
128(4)
2.2.2 Euphorbia Fischeriana Steud
132(3)
2.2.3 Vitex Rotundifolia L.f
135(3)
2.2.4 Isodon Rubescens (Hemsl.) H. Hara
138(3)
References
141(6)
Topic 2.3 Triterpenes
147(120)
2.3.1 Alisma Orientale (Sam.) Juz
147(4)
2.3.2 Schisandra Henryi C.B. Clarke
151(15)
2.3.3 Cucurbita Pepo L
166(12)
2.3.4 Brucea Javanica (L.) Merr
178(13)
2.3.5 Dictamnus Dasycarpus Turcz
191(17)
2.3.6 Pulsatilla Chinensis (Bunge) Regel
208(15)
2.3.7 Clinopodium Chinense (Benth.) Kuntze
223(21)
References
244(23)
Chapter 3 Phenolics
267(114)
Introduction
267(2)
Topic 3.1 Benzopyrones
269(72)
3.1.1 Morus Australis Poir
269(20)
3.1.2 Hedyotis Biflora (L.) Lam
289(17)
3.1.3 Garcinia Oligantha Merr
306(22)
References
328(13)
Topic 3.2 Quinones
341(28)
3.2.1 Juglans Mandshurica Maxim
341(13)
3.2.2 Rubia Cordifolia L
354(7)
References
361(8)
Topic 3.3 Lignans
369(12)
3.3.1 Houpoea Obovata (Thunb.) N.H. Xia & C.Y. Wu
369(9)
References
378(3)
Index of Natural Products 381(10)
Index of Oncological and Related Terms 391(6)
Index of Plants 397(6)
Subject Index 403
Dr. Christophe Wiart is a French pharmacist who for the last 25 years has traveled in various parts of Asia to study in situ the botany, the ancient traditional knowledge, and ethnopharmacology of medicinal plants to bring global awareness both in public and academia on the tremendous pharmaceutical value of medicinal plants of Asia and the Pacific. He has authored more than 14 academic books on this subject as well as peer-reviewed research papers. He was recently interviewed by BBC Radio Crowd Science (2020). He appeared on HBO's Vice (TV Series) in season 3, episode 6 (episode 28 of the series), titled "The Post-Antibiotic World & Indonesia's Palm Bomb." aired on April 17, 2015. Dr. Wiart was a guest in Aljazeera Inside Story " For only the fourth time in its 70-year history, the United Nations is holding a special meeting devoted to a health crisis." Dr. Christophe Wiart is a French pharmacist who for the last 25 years has traveled in various parts of Asia to study in situ the botany, the ancient traditional knowledge, and ethnopharmacology of medicinal plants to bring global awareness both in public and academia on the tremendous pharmaceutical value of medicinal plants of Asia and the Pacific. He has authored more than 14 academic books on this subject as well as peer-reviewed research papers. He was recently interviewed by BBC Radio Crowd Science (2020). He appeared on HBO's Vice (TV Series) in season 3, episode 6 (episode 28 of the series), titled "The Post-Antibiotic World & Indonesia's Palm Bomb." aired on April 17, 2015. Dr. Wiart was a guest in Aljazeera Inside Story " For only the fourth time in its 70-year history, the United Nations is holding a special meeting devoted to a health crisis."
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