Muutke küpsiste eelistusi

E-raamat: Lipid Signaling in Human Diseases

Edited by , Edited by
Teised raamatud teemal:
  • Formaat - PDF+DRM
  • Hind: 159,93 €*
  • * hind on lõplik, st. muud allahindlused enam ei rakendu
  • Lisa ostukorvi
  • Lisa soovinimekirja
  • See e-raamat on mõeldud ainult isiklikuks kasutamiseks. E-raamatuid ei saa tagastada.
Lipid Signaling in Human DiseasesSuurem pilt
Teised raamatud teemal:

DRM piirangud

  • Kopeerimine (copy/paste):

    ei ole lubatud

  • Printimine:

    ei ole lubatud

  • Kasutamine:

    Digitaalõiguste kaitse (DRM)
    Kirjastus on väljastanud selle e-raamatu krüpteeritud kujul, mis tähendab, et selle lugemiseks peate installeerima spetsiaalse tarkvara. Samuti peate looma endale  Adobe ID Rohkem infot siin. E-raamatut saab lugeda 1 kasutaja ning alla laadida kuni 6'de seadmesse (kõik autoriseeritud sama Adobe ID-ga).

    Vajalik tarkvara
    Mobiilsetes seadmetes (telefon või tahvelarvuti) lugemiseks peate installeerima selle tasuta rakenduse: PocketBook Reader (iOS / Android)

    PC või Mac seadmes lugemiseks peate installima Adobe Digital Editionsi (Seeon tasuta rakendus spetsiaalselt e-raamatute lugemiseks. Seda ei tohi segamini ajada Adober Reader'iga, mis tõenäoliselt on juba teie arvutisse installeeritud )

    Seda e-raamatut ei saa lugeda Amazon Kindle's. 

Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their reaction products have been implicated in fundamental cellular processes including cell proliferation, division and migration. These enzymes and their products underlie the molecular mechanisms of numerous human diseases, in particular metabolic disease (diabetes), cancer, neurodegenerative disease and cardiovascular disease.

Over the last decade, studies have advanced to the point that a number of inhibitors for these enzymes have been developed to attempt to ameliorate these conditions; some of the inhibitors are currently in human clinical trial. The need for this book is to review the current status of this field and the prospect for the inhibitors to be clinically important.

 

Part 1. New Roles for Sphingolipid Signaling and Cell Function.-
1. Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma.-
2. Exploring the Therapeutic Landscape of Sphingomyelinases.-
3. Sphingosine kinases as druggable targets.- Part 2. Phospholipase D and Mitogen Phosphatidic Acid in Human Disease.-
4. Prospects for PLD inhibition in cancer and thrombotic disease.-
5. Phospholipase D and the Mitogen Phosphatidic Acid in Human Disease: Inhibitors of PLD at the Crossroads of Phospholipid Biology and Cancer.-
6. Role of Phospholipase D-Derived Phosphatidic Acid in Regulated Exocytosis and Neurological Disease.- Part 3. Lipid Kinases and Novel Regulatory Pathways.-
7. Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors.-
8. Functions of Nuclear Polyphosphoinositides.- Part 4. Bioactive Lipids in Health and Disease.-
9. Platelet-Activating Factor as an Effector for Environmental Stressors.-
10. Phospholipase D and Choline Metabolism.- Part 5- Lipids and Membrane Microdomains.-
11. Regulation of Inositol Biosynthesis: Balancing Health and Pathophysiology.-
12. Lipids and Membrane Microdomains: The Glycerolipid and Alkylphosphocholine Class of Cancer Chemotherapeutic Drugs.- Part 6. Nuclear Trafficking of Lipids.-
13. Inositide-Dependent Nuclear Signalling in Health and Disease.-
14. Lipids in Exosome Biology.
Lisainfo e-raamatute kohta Lisainfo e-raamatute kohta
Püsilink: https://www.kriso.ee/db/97830303366842e.html
Märksõnad: