Liquid chromatography (LC), particularly high performance LC, is an important technique for the analysis of chemical mixtures used in laboratories in the life and pharmaceutical sciences. International contributors discuss developments in this field; models of chromatography; liquid separation technology; LC phases, principles, and instrumentation of various types of chromatography; detectors for LC; and related theory and methodologies. Trends such as miniaturization of HPLC systems are also discussed. The book includes guidelines for selecting solvents, and supporting figures, tables, and equations. The editors' affiliations are as follows: Fanali (Institute of Chemical Methodologies, Italian National Council of Research, Rome); Haddad (chemistry, U. of Tasmania, Australia); Poole (chemistry, Wayne State U., Detroit, US); Schoenmakers (analytical chemistry, University of Amsterdam, the Netherlands); and Lloyd (mechanical engineering, Griffiths U., Brisbane, Australia). Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)
A single source of authoritative information on all aspects of the practice of modern liquid chromatography suitable for advanced students and professionals working in a laboratory or managerial capacity
- Chapters written by authoritative and visionary experts in the field provide an overview and focused treatment of a single topic
- Comprehensive coverage of modern liquid chromatography from theory, to methods, to selected applications
- Thorough selected references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision making
- Extensive original tables and figures, placing recent research developments into a general context
- Worked examples, intuitive explanations, and clear figures reinforce learning
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"...written for a wide array of scientists from novices to more experienced analytical chemists...provides the tools needed in a research lab to help establish and select liquid phase separation methods." -Analytical and Bioanalytical Chemistry, Oct 30, 2014
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A single source of authoritative information on all aspects of the practice of modern liquid chromatography suitable for advanced students and professionals working in a laboratory or managerial capacity
Milestones in the Development of Liquid Chromatography
Kinetic Theory of Liquid Chromatography
Column Technology in Liquid Chromatography
Reversed-phase Liquid Chromatography
Secondary Chemical Equilibria in Reversed-Phase Liquid Chromatography
Hydrophilic Interaction Liquid Chromatography
Hydrophobic Interaction Liquid Chromatography
Liquid-Solid Chromatography
Ion Chromatography
Size-exclusion chromatography
Solvent Selection for Liquid Chromatography
Method development in Liquid Chromatography
Theory and Practice of Gradient Elution Liquid Chromatography
Coupled-Column Liquid Chromatography
General Instrumentation
Advanced Spectroscopic Detectors for Identification and Quantification: Mass
Spectrometry
Advanced Spectroscopic Detectors for Identification and Quantification: FTIR
and Raman
Advanced Spectroscopic Detectors for Identification and Quantification:
Nuclear Magnetic Resonance
Data Analysis Methods
Quantitative Structure-Retention and Property Relationships
Modeling of Preparative Liquid Chromatography
Process Concepts in Preparative Liquid Chromatography
Preparative Chromatography of Biopolymers
Miniaturization and Microfluidics
Capillary Electrochromatography
Salvatore Fanali is Director of Research at the Institute of Chemical Methodologies, Italian National Research Council (C.N.R.) in Monterotondo (Rome), Italy, and head of the Capillary Electromigration and Chromatographic Methods Unit at the same Institute. His research activity is mainly focused on separation science including the development of modern miniaturized techniques (electrodriven and liquid chromatography). He also studies hyphenation with mass spectrometry and development of new stationary phases. Separation methods developed are currently applied to food, pharmaceuticals, chiral environment, and biomedical analysis. He is Editor of the Journal of Chromatography A and a member of the advisory editorial board of seven international scientific journals. Fanali is the author of about 300 publications including some book chapters. He received several awards including the Liberti Medal” in Separation Science from the Italian Chemical Society. Paul Haddad is currently a Distinguished Professor of Chemistry and Australian Research Council Federation Fellow at the University of Tasmania, as well as Director of the Pfizer Analytical Research Centre. He has more than 500 publications in this field and has presented in excess of 450 papers at local and international scientific meetings. He is an editor of Journal of Chromatography A, a contributing editor for Trends in Analytical Chemistry, and was an editor of Analytica Chimica Acta for 6 years. He is currently a member of the editorial boards of 10 other journals of analytical chemistry or separation science.
He is the recipient of several national and international awards, including the ACS Award in Chromatography, the Marcel Golay Award, the AJP Martin Gold Medal awarded by the Chromatographic Society, the Royal Society of Chemistry Analytical Separation Methods Award, the RACI HG Smith and Analytical Division medals, and more. Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial International Symposium on High-Performance Thin-Layer Chromatography”. David Lloyd obtained his PhD from the Department of Chemistry, University of York, UK, working with Prof. David Goodall on the development of laser-based polarimetry as a chiral detection method. He then completed postdoctoral research on bioanalytical capillary electrophoresis (CE) with Prof. Irving Wainer at St. Jude Childrens Research Hospital in Memphis, TN. He has since worked both in academia (McGill University, Departments of Oncology and Experimental Medicine) and the pharmaceutical industry (DuPont Pharmaceuticals and Bristol-Myers Squibb). Whilst at McGill, Dr. Lloyds analytical research focused on microscale bioanalysis by CE and on chiral CE. Since moving to the pharmaceutical industry, his responsibilities have been in analytical R&D for projects ranging from the late discovery stage through worldwide registrational filings, with a primary focus on separations science. From 1995 2002, Dr. Lloyd was Contributing Editor of TrAC - Trends in Analytical Chemistry; and from 1999 - 2011, he was Editor of the Journal of Chromatography B.
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