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E-raamat: Mitochondrial Medicine: Volume 3: Manipulating Mitochondria and Disease- Specific Approaches

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  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2277
  • Ilmumisaeg: 02-Jun-2021
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071612705
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  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2277
  • Ilmumisaeg: 02-Jun-2021
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071612705
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This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine. Volume III guides readers through chapters on intercellular mitochondrial transfer, Cytoplasmic transfer methods, Ndufs4 knockout mouse, in vivo assessment of mitochondrial oxygen consumption, mitochondrial network analysis by imaging, mitochondrial respiration in platelets, Heterologous Inferential Analysis (HIA), bioenergetic profiling, integrative methods for studying cardiac energetics, and isolation and deep sequencing of mitochondrial DNA.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and accessible, Mitochondrial Medicine, Second Edition, Volume 3: Manipulating Mitochondria and Disease- Specific Approaches aims to be a comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.

 

 

Allotopic Expression of ATP6 in the Mouse as a Transgenic Model of
Mitochondrial Disease.- Mitochondrial Transplantation for Ischemia
Reperfusion Injury.- Quantitatively Controlled Intercellular Mitochondrial
Transfer by Cell Fusion-Based Method Using a Microfluidic Device.- Lipophilic
Conjugates for Carrier-Free Delivery of RNA Importable Into Human
Mitochondria.- Drug Discovery Assay to Identify Modulators of the
Mitochondrial Ca2+ Uniporter.- Cytoplasmic Transfer Methods for Studying the
Segregation of Mitochondrial DNA in Mice.- Electron Attachment to Isolated
Molecules as a Probe To Understand Mitochondrial Reductive Processes.-
Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function
in Severe Inflammation.- Assessment of the Effects of Drugs on Mitochondrial
Respiration.- The Ndufs4 Knockout Mouse: A Dual Threat Model of Childhood
Mitochondrial Disease and Normative Aging.- Suborganellar Localisation of
Mitochondrial Proteins and Transcripts in Human Cells.- In vivo Assessment of
Mitochondrial Oxygen Consumption.- Update of Mitochondrial Network Analysis
by Imaging: Proof of Technique in Schizophrenia.- Heterologous Inferential
Analysis (HIA) and other Emerging Concepts In Understanding Mitochondrial
Variation in Pathogenesis: There is no More Low Hanging Fruit.- Accurate
Measurement of Cellular and Cell-Free Circulating Mitochondrial DNA Content
from Human Blood Samples Using Real Time Quantitative PCR.- Measurement of
Mitochondrial Respiration in Platelets.- Isolation and Electron Microscopic
Analysis of Liver Cancer Cell Mitochondria.- Assessment of Mitochondrial
Reactive Oxygen Species and Redox Regulation in Stem Cells.- Single Cell
Approaches for Studying the Role of Mitochondrial DNA in Neurodegenerative
Disease.- A New Method for Sequencing the Mitochondrial Genome by Using Long
Read Technology.- Mitochondrial DNA as a Sensitive Biomarker of UV-induced
Cellular Damage in Human Skin.- Isolation of Mitochondria-associated ER
Membranes (MAMs), Synaptic MAMs and Glycosphingolipid Enriched Microdomains
(GEMs) from Brain Tissues and Neuronal Cells.- Mitochondrial Diagnostics: A
Discovery-Based Biochemical Platform for Phenotyping Human Peripheral Blood
Cell Mitochondria.- Bioenergetic Profiling Of Human Pluripotent Stem Cells.-
Integrative Methods for Studying Cardiac Energetics.- Isolation of
Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application
Of High Resolution Respirometric Assay (XFe96 Seahorse assay).- The Isolation
and Deep Sequencing of Mitochondrial DNA.- Ultrastructure of the
Mitochondria-Associated Membranes in Human Tumor Specimens.