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E-raamat: Modeling Biology: Structures, Behaviors, Evolution

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Abstract and conceptual models have become an indispensable tool for analyzing the flood of highly detailed empirical data generated in recent years by advanced techniques in the biosciences. Scientists are developing new modeling strategies for analyzing data, integrating results into the conceptual framework of theoretical biology, and formulating new hypotheses. In Modeling Biology, leading scholars investigate new modeling strategies in the domains of morphology, development, behavior, and evolution.

The emphasis on models in the biological sciences has been accompanied by a new focus on conceptual issues and a more complex understanding of epistemological concepts. Contributors to Modeling Biology discuss models and modeling strategies from the perspectives of philosophy, history, and applied mathematics. Individual chapters discuss specific approaches to modeling in such domains as biological form, development, and behavior. Finally, the book addresses the modeling of these properties in the context of evolution, with a particular emphasis on the emerging field of evolutionary developmental biology (or evo-devo).

Contributors:
Giorgio A. Ascoli, Chandrajit Bajaj, James P. Collins, Luciano da Fontoura Costa, Kerstin Dautenhahn, Nigel R. Franks, Scott Gilbert, Marta Ibanes Miguez, Juan Carlos Izpisua-Belmonte, Alexander S. Klyubin, Thomas J. Koehnle, Manfred D. Laubichler, Sabina Leonelli, James A. R. Marshall, George R. McGhee Jr., Gerd B. Muller, Chrystopher L. Nehaniv, Karl J. Niklas, Lars Olsson, Eirikur Palsson, Daniel Polani, Diego Rasskin Gutman, Hans-Jorg Rheinberger, Alexei V. Samsonovich, Jeffrey C. Schank, Harry B. M. Uylings, Jaap van Pelt, and Iain Werry

Experts examine new modeling strategies for the interpretation of biological data and their integration into the conceptual framework of theoretical biology, detailing approaches that focus on morphology, development, behavior, or evolution.
Series Foreword ix
Preface xi
I. INTRODUCTION
1(10)
Models in Theoretical Biology
3(8)
Manfred D. Laubichler
Gerd B. Muller
II. CONCEPTUAL ISSUES
11(60)
What Is in a Model? Combining Theoretical and Material Models to Develop Intelligible Theories
15(22)
Sabina Leonelli
Experimental Model Systems: An Epistemological Apercu from the Perspective of Molecular Biology
37(10)
Hans-Jorg Rheinberger
The Role of Complex Networks in Biological Modeling and Systems Biology
47(24)
Luciano da Fontoura Costa
III. FORM
71(68)
Modeling the Spectrum of Existent, Nonexistent, and Impossible Biological Form: A Research Program
75(16)
George R. McGhee
Computational Models of Dendritic Morphology: From Parsimonious Description to Biological Insight
91(24)
Alexei V. Samsonovich
Giorgio A. Ascoli
Geometric Modeling and Quantitative Visualization of Virus Ultrastructure
115(24)
Chandrajit Bajaj
IV. DEVELOPMENT
139(78)
Modeling Developmental Asymmetries
143(22)
Diego Rasskin-Gutman
Marta Ibanes Miguez
Juan Carlos Izpisua-Belmonte
Modeling Wave Propagation, Chemotaxis, Cell Adhesion, and Cell Sorting: Examples with Dictyostelium, Using a 3-D Cell-Based Model
165(30)
Eirikur Palsson
Modeling Neuronal Growth and Shape
195(22)
Jaap van Pelt
Harry B. M. Uylings
V. BEHAVIOR
217(84)
Modeling Complex Biobehavioral Systems
219(22)
Jeffrey C. Schank
Thomas J. Koehnle
Information-Theoretic Modeling of Sensory Ecology: Channels of Organism-Specific Meaningful Information
241(42)
Chrystopher L. Nehaniv
Daniel Polani
Lars Olsson
Alexander S. Klyubin
Human-Robot Interaction as a Model for Autism Therapy: An Experimental Study with Children with Autism
283(18)
Iain Werry
Kerstin Dautenhahn
VI. EVOLUTION
301(78)
Modeling Optimization and Early Land Plant Evolution
305(30)
Karl J. Niklas
Computer Modeling in Behavioral and Evolutionary Ecology: Whys and Wherefores
335(20)
James A. R. Marshall
Nigel R. Franks
Modeling in EvoDevo: How to Integrate Development, Evolution, and Ecology
355(24)
James P. Collins
Scott Gilbert
Manfred D. Laubichler
Gerd B. Muller
Contributors 379(2)
Index 381