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E-raamat: Molecular Hydrogen in Health and Disease

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Molecular hydrogen (H2) has emerged as a promising therapeutic and preventive medical gas. Hydrogen gas has garnered significant attention in recent years due to its remarkable antioxidant and anti-inflammatory properties. H2 exhibits exceptional pharmacokinetics, swiftly traversing cellular biomembranes to access subcellular organelles indirectly regulating hormones and cytokines through various signal transduction pathways. H2 has the potential to address a wide range of issues, including clinical medical treatment in the areas of healthcare: myocardial ischemia, heart failure, cardiac arrest, metabolic syndrome, advanced-stage cancer, inflammatory diseases, Alzheimer's dementia, aging-related disorders, sports activities, and even beauty, agriculture, etc.

Selected world-known authors in the field provide readers with a comprehensive overview of molecular hydrogen's remarkable effects and its physical, chemical, and therapeutic properties and potential in biomedical applications. This contributed volume fills the current gap in information and is intended for everyone who wants to be better informed about the wide possibilities of using molecular hydrogen. However, it is mainly intended for use by medical students, physiologists, pharmacologists, physicians, and other healthcare personnel who can use molecular hydrogen to improve the health of everyone who needs it.


Hydrogen: From Stars to Fuel to Medicine.- An exploration of the direct
biological targets of molecular hydrogen.- Prospects of hydrogen medicine
based on its protective effects on mitochondrial function.- Molecular
hydrogen: A new treatment strategy of mitochondrial disorders.- Autonomic
cardiac regulation in response to exercise and molecular hydrogen
administration in well-trained athletes.- The Clinical Use of Hydrogen as a
Medical Treatment.- Homeostatic and endocrine response underlying protective
effects by molecular hydrogen.- Radiation-induced heart disease: potential
role for molecular hydrogen.- Short-lasting supplementation with molecular
hydrogen and vitamin E upregulates myocardial connexin-43 in irradiated and
non-irradiated rat heart.- Molecular hydrogen: a new protective tool against
radiation-induced toxicity.- Role of Matrix Metalloproteinases in Effects of
Molecular Hydrogen.- Perioperative mitigation of oxidative stress with
molecular  hydrogen during simulated heart transplantation in pigs.-
Application of Hydrogen in Hemodialysis: A brief review with emphasis on the
quantification of dissolved H2.- Hydrogen as a potential therapeutic approach
in the treatment of cancer: from bench to bedside.- The Role of the Smallest
Molecule  Hydrogen Overcoming Ageing-Related Disease.- Dihydrogen and Hepatic
Function: Systematic Review and Meta-Analysis.- Hydrogen-rich water using as
a modulator of gut microbiota and managing the inflammatory bowel diseases.-
Effects of Molecular Hydrogen in the  Pathophysiology and Management of
Metabolic and Non-communicable Diseases.- Consumption of Hydrogen-Treated
Foods Provides Nutritional and Health Benefits.- Differential effects of
carbohydrates on the generation of hydrogen and methane in low- and
high-methane-producing rats.- Natural Biomolecules, Plant Extracts and
Molecular Hydrogen New Antioxidant Alternatives in the Management of Male
Infertility.- Comparison of free-radical scavenging activity of various
sources of molecular hydrogen.- Development of a preclinical tool for
measuring percutaneous transfer of dihydrogen, with a view to optimizing
medical devices adapted to focal therapies in dermatology.- Intraosseous
Administration of Molecular Hydrogen: A Novel Technique From Molecular
Effects To Tissue Regeneration.- Perspective of nanomaterials and
nanomedicine procedures in molecular hydrogen therapy.- The emergence,
development, and future mission of hydrogen medicine and biology.