Cancer care has changed dramatically with the development of new treatments. Overall survival, as well as disease free survival and progression free survival, has been changing in favor of prolonged times making surgical approaches different when musculoskeletal metastasis developed and allowing the development of new technologies as well.
This book brings together current evidence-based approaches to surgically treat musculoskeletal metastasis keeping in consideration a multidisciplinary approach. Chapters not only describe state-of-the-art surgical techniques and options to treat these patients, but also different scenarios of metastatic spread and how other specialties intervene to obtain the best oncological and functional outcomes in these patients.
This book will serve as a comprehensive guide for musculoskeletal oncology surgeons, medical oncologists, radiation oncologists and other healthcare professionals involved in the multidisciplinary management of musculoskeletal metastasis. The combination of practical principles, advanced technologies, and ethical considerations aims to provide a holistic approach to enhance patient care and outcomes.
Section I: General Concepts.-1. Overview of Musculoskeletal
Metastases.-2. Understanding Musculoskeletal Metastasis.-3. Multidisciplinary
Treatment of Musculoskeletal Metastases.- Section II: Patient Assessment &
Diagnostic Approach.-4. Patient Assessment and Selection.-5. Nutritional
Evaluation of Patients with Metastatic Disease.-6. Radiological Assessment:
From Plain Radiographs to Advanced Cross-Sectional Studies.-7. Obtaining
tissue samples: Whats the best approach?.-8. Pathological Assessment of
metastatic disease to the musculoskeletal system.-9. Has my cancer spread?
Staging strategies.-10. I am not crazy: Why do I need to see a mental health
specialist?.- Section III: Principles of Surgical Intervention.-11. Overview
of surgical indications and outcomes.-12. Oops ... this is about to
break!Impending Pathological Fractures of long bones.-13. Management of
Spinal Metastatic Disease.-14. Management of pelvic metastasis Minimally
Invasive Pelvic Surgery.-15. Management of pelvic metastasis: Open Surgical
Techniques.-16. Management of Shoulder Gridle Metastatic Disease.-17.
Management of Diaphyseal Humeral Metastases.-18. Management of Metastatic
Disease Around the Elbow.-19. Management of metastatic disease around the
forearm, wrist & hand.-20. Management of metastatic disease to the proximal
femur.-21. Management of metastatic desiase to the femoral diaphysis.-22.
Management of metastatic disease around the Knee.- Management of metastatic
disease to the tibial shaft.-24. Management of metastatic disease to the foot
and ankle.- Section IV: Principles of Medical Treatment.-25.Medical
management of musculoskeletal metastasis from breast cancer.-26. Medical
management of musculoskeletal metastasis from prostate cance.-27. Medical
management of musculoskeletal metastasis from lung cancer.-28. Medical
management of musculoskeletal metastasis from renal cell carcinoma.-29.
Medical management of musculoskeletal metastasis from thyroid carcinoma.-30.
Medical management of Multiple Myeloma: An Orthopedic Blood Cancer.-31.
Radiation Oncology Strategies for the management of musculoskeletal
metastasis..- Section V: Rehabilitation & Post-operative Care.-32. Physical
Therapy Strategies.-33. Pain Management Protocols.-34. Multidisciplinary Care
Clinics for Patients with Metastatic Bone Disease.- Section VI:
Oligometastatic Disease.-35. Metastasectomy for Musculoskeletal
OligometastasesSurgical Point of View.-36. Principles of Surgical
Management: Ablative Techniques for Skeletal Metastases.-37. Radiation
Strategies in Oligometastatic disease.- Section VII: Especial
Scenarios.-38.Skeletal Metastasis of Unknown Primary: Now What should I
do?.-39. Isolated Lytic Lesions- where is this coming from?.-40. Soft tissue
metastases from carcinomas and sarcomas - what is this about?.-41.
Post-radiation pathological fractures - this bone is not healing !!!.-42.
Ethical Considerations in Musculoskeletal Metastasis Management.-43.
Comprehensive Percutaneous Intervention for Skeletal Metastases:
Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF).- Section VIII:
What comes after treatment & Future Direction.-44. Survivorship and Quality
of Life.-45. Future Directions in Multidisciplinary Musculoskeletal Oncology.
Juan A. Pretell, MD, FAAOS
Professor, Orthopedic Surgery
Florida International University
Program Director, Orthopedic Surgery Program
Baptist Health South Florida / Florida International University.
Chief of Musculoskeletal Oncology
Miami Cancer Institute
Baptist Health of South Florida.
Kendall, FL
Santiago Lozano-Calderon, MD, PhD, FAAOS, FAOA
Program Director Harvard Combined Musculoskeletal Oncology Fellowship
Musculoskeletal Oncology Service
Department of Orthopaedic Surgery
Massachusetts General Hospital
Mass General Brigham Cancer Institute Endowed Chair VII
Associate Professor in Orthopedic Surgery
Harvard Medical School
Boston, MA