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E-raamat: Muscle Diseases: A Guide to Differential Diagnosis, Investigation and Management

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  • Formaat: 226 pages
  • Ilmumisaeg: 05-Feb-2025
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9780429769641
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  • Formaat: 226 pages
  • Ilmumisaeg: 05-Feb-2025
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9780429769641

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A how-to-guide on the clinical assessment and investigation of patients presenting with muscle-related symptoms. Featuring a case-based approach, this accessible text is suitable for a wide range of clinical specialists who see patients presenting with both common and rare muscle diseases.

This volume is a how-to guide on the clinical assessment and investigation of patients presenting with muscle-related symptoms. Featuring a case-based approach, this accessible text is suitable for a wide range of clinical specialists who see patients presenting with both common and rare muscle diseases.

Muscle diseases are often initially missed or misdiagnosed, as they are uncommon disorders and can present in a variety of ways, often mimicking other more common disorders. Careful assessment of the history, physical examination and appropriate choice of investigations is therefore essential to reaching a diagnosis and providing short- and long-term effective management plans. Key features of this resource include:

  • A case-based approach using real cases seen in clinical practice and highlighting different clinical presentations
  • Case vignettes that cover patient history, examination, investigations, diagnosis and discussion points to assist the reader in developing a mental framework for thinking about muscle disease and approaching diagnosis
  • The relevant investigations (including muscle biopsy, neurophysiology and muscle imaging) required for each clinical scenario, aiding the clinician in clinicopathological correlation
  • Being concise, practical and complemented by a wide range of figures to enhance understanding

Patients with muscle diseases may be referred to one of several medical or surgical specialties, including neurology, rheumatology, neuropathology, neurophysiology, cardiology, respiratory medicine, intensive care medicine, gastroenterology, ophthalmology, orthopaedic and spinal surgery, before the correct diagnosis is considered. This accessible text is an ideal resource for clinicians.



A how-to-guide on the clinical assessment and investigation of patients presenting with muscle-related symptoms. Featuring a case-based approach, this accessible text is suitable for a wide range of clinical specialists who see patients presenting with both common and rare muscle diseases.

Preface. About the editors. List of contributors. Introduction. Abbreviations.
Chapter 1 History.
Chapter 2 Muscle examination.
Chapter 3 Serological tests.
Chapter 4 Muscle antibodies.
Chapter 5 Neurophysiology.
Chapter 6 Muscle biopsy.
Chapter 7 Muscle imaging.
Chapter 8 Genetic investigations in neuromuscular diseases.
Chapter 9 Management, treatment and therapy for neuromuscular conditions.
Chapter 10 Closing comments. Section Cases. Case
1. Case
2. Case
3. Case
4. Case
5. Case
6. Case
7. Case
8. Case
9. Case
10. Case
11. Case
12. Case
13. Case
14. Case
15. Case
16. Case
17. Case
18. Case
19. Case
20. Case
21. Case
22. Case
23. Case
24. Case
25. Case
26. Case
27. Case
28. Case
29. Case
30. Case
31. Case
32. Case
33. Case
34. Case
35. Case
36. Index.

Dr Andria FA Merrison, MA MBChB MD FRCP is a Consultant Neurologist based in North Bristol NHS Trust and is the Director of the South West Neuromuscular Operational Delivery Network and the Bristol Motor Neurone Disease Centre.

Dr Stefen Brady BA, MB, BCh, BAO, FRCP, DPhil is a Consultant Neurologist and Clinical Lead of the Oxford Adult Muscle and Spinal Muscular Atrophy (SMA) Services, Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford.