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E-raamat: Nanomedicine and Drug Delivery

Edited by (Elisabethinin Hospital, Klagenfurt, Austria), Edited by (Mahatma Gandhi University, Kerala, India), Edited by (Canadian Research and Development Center of Sciences and Cultures (CRDCSC), Montreal, Quebec, Canada)
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In this first volume of a new series, international contributors in nanobiology, applied physics, biochemistry, and clinical pharmacology shed light on recent advances in nanomedicine and drug delivery. Covering the promise and potential of nanomedicine as well as possible dangers, they consider the full range of nanomedical applications which employ molecular nanotechnology inside the human body. Some specific topics examined include colloidal delivery systems for phytochemicals, nanoparticles as adjuvants for mucosal vaccine delivery, and biosynthesis of silver nanoparticles and their antimicrobial activity. Other subjects are gold peptide nanoparticle activation of macrophages, capsules based on lipid vesicles, and effects of intranasal interferon-alpha on rat behavior. The book includes b&w images and illustrations. Sebastian is affiliated with the Ayurveda and Vein Clinic, Austria. The book is distributed in the US by CRC Press, a Taylor & Francis Group. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com)

This forward-looking book focuses on the recent advances in nanomedicine and drug delivery. It outlines the extraordinary new tools that have become available in nanomedicine and presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices into applications as quickly as possible, while also considering the possible dangers of nanomedicine.

The book considers the full range of nanomedicinal applications that employ molecular nanotechnology inside the human body, from the perspective of a future practitioner in an era of widely available nanomedicine.

Written by some of the most innnovative minds in medicine and engineering, this unique volume will help professionals understand cutting-edge and futuristic areas of research that can have tremendous payoff in terms of improving human health. Readers will find insightful discussions of nanostructured intelligent materials and devices that are considered technically feasible and which have a high potential to produce advances in medicine in the near future.

Topics include:

  • Health benefits of phytochemicals and the application of colloidal delivery systems
  • Study of non-covalent attachment of recombinant targeting proteins to polymer-modified Adenoviral gene delivery vectors
  • The role of nanoparticles as adjuvants for mucosal vaccine delivery
  • Poly(amido-amine)s as delivery styems for biologically active substances
  • Antimicrobial activity of silver nanoparticles
  • Nanomedicine in the use of cancer treatment
  • Dendrimers, capsules based on lipid vesicles for drug delivery
  • Many other recent achievements
List of Contributors
ix
List of Abbreviations
xv
Preface xix
1 Ethosomes as Non-invasive Loom for Transdermal Drug Delivery System
1(16)
C.K. Sudhakar
Nitish Upadhyay
Sanjay Jain
R. Narayana Charyulu
2 Colloidal Delivery Systems for Phytochemicals
17(16)
Ashok R. Patel
3 Polymer-modified Gene Delivery Vectors Retargeted with Recombinant Proteins
33(6)
R. Pola
M. Pechar
K. Ulbrich
R. C. Carlisle
R. A. Willemsen
L. W. Seymour
4 Study of Drug Transport Properties of Acrylic Based Iron (III) Oxide Filled IPN
39(12)
S. Goswami
K. Kiran
A. B. Panda
P. P. Sharma
S. K. Mahapatra
S. V. Bhoraskar
I. Banerjee
5 Poly(Amido-amine)s as Carriers for Intracellular Delivery of Drugs and Proteins
51(14)
Fabio Fenili
Elena Ferrari
Amedea Manfredi
Roberta Cavalli
Simon C. W. Richardson
Elisabetta Ranucci
Paolo Ferruti
6 Nanoparticles as Adjuvant(S) for Mucosal Vaccine Delivery
65(22)
PN Gupta
GD Singh
SC Sharma
S Singh
MK Tikoo
N Gupta
RK Johri
7 Biosynthesis of Silver Nanoparticles, Characterization and Their Antimicrobial Activity
87(8)
K. Mallikarjuna
G. Narasimha
B. V. Subba Reddy
B. Sreedhar
G. R. Dillip
B. Deva Prasad Raju
8 Gold-peptide Nanoparticles Activation of Macrophages
95(6)
Jagat R. Kanwar
Ganesh Mahidhara
Rupinder K. Kanwar
9 Combating Infectious Diseases: Nanotechnology-based Drug Delivery
101(30)
Zahoor Ahmad
Rajesh Panday
10 Dendrimers in Biology and Medicine
131(14)
Dzmitry Shcharbin
Volha Dzmitruk
Inessa Halets
Elzbieta Pedziwiatr-Werbicka
Maria Bryszewska
11 Capsules Based on Lipid Vesicles: Potentiality for Drug Delivery
145(16)
Brigitte Pepin-Donat
Francois Quemeneur
Marguerite Rinaudo
Clement Campillo
12 A Simulation Study on the Transport of Ions Through Ion Channels
161(14)
Keka Talukdar
Apurba Krishna Mitra
13 Effects of Intranasal Administration of Interferon-alpha on Rat Behavior
175(12)
N.A. Loginova
K. Yu. Sarkisova
O. V. Kurskaya
E. V. Loseva
14 Neurotransplantation of Neural and Mesenchymal Stem Cells for Correction of Posthypoxic Disorders
187(12)
E. V. Loseva
O. V. Podgornyi
R. A. Poltavtseva
M. V. Marey
N. A. Loginova
O. V. Kurskaya
G. T. Sukhikh
R. K. Chilachyan
M. A. Aleksandrova
15 Spray Drying in Pharmaceutical Manufacturing an Overview
199(18)
Prathima Srinivas
16 RNA nanotechnology in Nanomedicine
217(14)
Wade W. Grabow
Kirill A. Afonin
Paul Zakrevsky
Faye M. Walker
Erin R. Calkins
Cody Geary
Wojciech Kasprzak
Eckart Bindewald
Bruce A. Shapiro
Luc Jaeger
References 231(58)
Index 289
Dr. Mathew Sebastian has a degree in surgery (1976) with specialization in Ayurveda. He holds several diplomas in acupuncture, neural therapy (pain therapy), manual therapy and vascular diseases. He was a missionary doctor in Mugana Hospital, Bukoba in Tansania, Africa (1976- 1978) and underwent surgical training in different hospitals in Austria, Germany, and India for more than 10 years. Since 2000 he is the doctor in charge of the Ayurveda and Vein Clinic in Klagenfurt, Austria. At present he is a Consultant Surgeon at Privatclinic Maria Hilf, Klagenfurt. He is a member of the scientific advisory committee of the European Academy for Ayurveda, Birstein, Germany, and TAM advisory committee (Traditional Asian Medicine, Sector Ayurveda) of the Austrian Ministry for Health, Vienna. He conducted an International Ayurveda Congress in Klagenfurt, Austria, in 2010. He has several publications to his name.

Neethu Ninan is doing joint doctoral research in nanomedicine and tissue engineering at both the University of South Brittany (Lorient, France) and the Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University, Kottayam, Kerala, India.

Dr. A. K. Hagh holds a BSc in urban and environmental engineering from the University of North Carolina (USA); an MSc in mechanical engineering from North Carolina A&T State University (USA); a DEA in applied mechanics, acoustics, and materials from the Université de Technologie de Compiègne (France); and a PhD in engineering sciences from the Université de Franche-Comté (France).

He has written about 1000 original articles, 250 monographs, and 170 chapters in 40 volumes. It is apparent from this work that he has made valuable contributions to the theory and practice of chemical engineering, heat and mass transfer, porous media, industrial drying, polymers, nanofibers, and nanocomposites.

Dr Haghi is Editor-In-Chief of the International Journal of Chemoinformatics and Chemical Engineering and Editor-In-Chief of the Polymers Research Journal. He is an editorial board member for many US and internationally published journals and is also a Senior Editor for Apple Academic Press (US and Canada).

He served as an associate member of the University of Ottawa and was a member of the Canadian Society of Mechanical Engineering.