Preface |
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xiii | |
Acknowledgments |
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xv | |
An Invitation |
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xvi | |
Authors |
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xvii | |
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1 Big Picture of the Small World |
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1 | (28) |
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1.1 Understanding the Atom: Ex Nihilo Nihil Fit |
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3 | (8) |
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1.2 Nanotechnology Starts with a Dare: Feynman's Big Little Challenges |
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11 | (4) |
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1.3 Why One-Billionth of a Meter Is a Big Deal |
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15 | (3) |
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1.4 Thinking It Through: The Broad Implications of Nanotechnology |
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18 | (7) |
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21 | (1) |
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1.4.2 Environmental Impact |
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21 | (2) |
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23 | (2) |
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1.5 The Business of Nanotech: Plenty of Room at the Bottom Line, Too |
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25 | (2) |
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27 | (1) |
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Recommendations for Further Reading |
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27 | (2) |
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2 Introduction to Miniaturization |
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29 | (18) |
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2.1 Background: The Smaller, the Better |
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29 | (1) |
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30 | (14) |
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2.2.1 The Elephant and the Flea |
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30 | (4) |
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2.2.2 Scaling in Mechanics |
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34 | (3) |
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2.2.3 Scaling in Electricity and Electromagnetism |
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37 | (1) |
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38 | (3) |
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2.2.5 Scaling in Heat Transfer |
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41 | (1) |
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42 | (1) |
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43 | (1) |
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2.3 Accuracy of the Scaling Laws |
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44 | (2) |
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Recommendations for Further Reading |
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46 | (1) |
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3 Introduction to Nanoscale Physics |
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47 | (32) |
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3.1 Background: Newton Never Saw a Nanotube |
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47 | (1) |
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3.2 One Hundred Hours and Eight Minutes of Nanoscale Physics |
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47 | (1) |
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3.3 The Basics of Quantum Mechanics |
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48 | (28) |
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3.3.1 Atomic Orbitals (Not Orbits) |
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49 | (3) |
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3.3.2 Electromagnetic Waves |
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52 | (4) |
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3.3.2.1 How Electromagnetic Waves Are Made |
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56 | (1) |
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3.3.3 The Quantization of Energy |
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57 | (4) |
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3.3.4 Atomic Spectra and Discreteness |
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61 | (1) |
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3.3.5 The Photoelectric Effect |
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61 | (5) |
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3.3.6 Wave-Particle Duality: The Double-Slit Experiment |
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66 | (1) |
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67 | (1) |
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68 | (1) |
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69 | (2) |
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3.3.7 The Uncertainty Principle |
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71 | (2) |
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73 | (3) |
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76 | (1) |
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Recommendations for Further Reading |
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77 | (2) |
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79 | (42) |
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4.1 Background: Matter Matters |
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79 | (1) |
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4.2 Bonding Atoms to Make Molecules and Solids |
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79 | (11) |
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81 | (2) |
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83 | (1) |
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84 | (1) |
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4.2.4 Walking through Waals: van der Waals Forces |
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84 | (2) |
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4.2.4.1 The Dispersion Force |
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86 | (1) |
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87 | (1) |
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4.2.4.3 van der Waals Force versus Gravity |
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88 | (2) |
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90 | (2) |
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4.4 Structures Small Enough to Be Different (and Useful) |
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92 | (26) |
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93 | (5) |
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4.4.1.1 Colloidal Particles |
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98 | (1) |
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98 | (2) |
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4.4.3 Films, Layers, and Coatings |
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100 | (3) |
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103 | (2) |
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4.4.5 Small-Grained Materials |
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105 | (3) |
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108 | (1) |
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4.4.6.1 Carbon Fullerenes and Nanotubes |
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109 | (6) |
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115 | (1) |
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115 | (3) |
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118 | (1) |
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Recommendations for Further Reading |
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119 | (2) |
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121 | (54) |
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5.1 Background: The Universe Mechanism |
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121 | (2) |
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5.1.1 Nanomechanics: Which Motions and Forces Make the Cut? |
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122 | (1) |
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5.2 A High-Speed Review of Motion: Displacement, Velocity, Acceleration, and Force |
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123 | (2) |
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5.3 Nanomechanical Oscillators: A Tale of Beams and Atoms |
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125 | (32) |
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126 | (1) |
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126 | (3) |
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5.3.1.2 Free Oscillation from the Perspective of Energy (and Probability) |
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129 | (3) |
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5.3.1.3 Forced Oscillation |
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132 | (2) |
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134 | (1) |
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5.3.2.1 The Lennard-Jones Interaction: How an Atomic Bond Is Like a Spring |
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135 | (4) |
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5.3.2.2 The Quantum Mechanics of Oscillating Atoms |
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139 | (2) |
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5.3.2.3 The Schrodinger Equation and the Correspondence Principle |
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141 | (5) |
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146 | (4) |
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5.3.3 Nanomechanical Oscillator Applications |
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150 | (1) |
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5.3.3.1 Nanomechanical Memory Elements |
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150 | (3) |
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5.3.3.2 Nanomechanical Mass Sensors: Detecting Low Concentrations |
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153 | (4) |
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157 | (15) |
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5.4.1 Scanning Probe Microscopes |
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158 | (1) |
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5.4.1.1 Pushing Atoms Around with the Scanning Tunneling Microscope |
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158 | (1) |
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5.4.1.2 Skimming across Atoms with the Atomic Force Microscope |
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159 | (5) |
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5.4.1.3 Pulling Atoms Apart with the AFM |
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164 | (4) |
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5.4.1.4 Rubbing and Mashing Atoms with the AFM |
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168 | (2) |
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5.4.2 Mechanical Chemistry: Detecting Molecules with Bending Beams |
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170 | (2) |
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172 | (1) |
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Recommendations for Further Reading |
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173 | (2) |
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175 | (44) |
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6.1 Background: The Problem (Opportunity) |
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175 | (1) |
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6.2 Electron Energy Bands |
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175 | (4) |
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6.3 Electrons in Solids: Conductors, Insulators, and Semiconductors |
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179 | (3) |
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182 | (3) |
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6.5 Density of States for Solids |
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185 | (1) |
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6.5.1 Electron Density in a Conductor |
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186 | (1) |
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6.6 Turn Down the Volume! (How to Make a Solid Act More Like an Atom) |
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186 | (1) |
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187 | (11) |
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189 | (2) |
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6.7.1.1 Uses for Quantum Structures |
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191 | (1) |
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6.7.2 How Small Is Small Enough for Confinement? |
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192 | (1) |
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6.7.2.1 Conductors: The Metal-to-Insulator Transition |
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193 | (1) |
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6.7.2.2 Semiconductors: Confining Excitons |
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194 | (2) |
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6.7.3 The Band Gap of Nanomaterials |
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196 | (2) |
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198 | (4) |
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6.9 Single-Electron Phenomena |
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202 | (9) |
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6.9.1 Two Rules for Keeping the Quantum in Quantum Dot |
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205 | (1) |
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6.9.1.1 Rule 1: The Coulomb Blockade |
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206 | (1) |
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6.9.1.2 Rule 2: Overcoming Uncertainty |
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207 | (1) |
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6.9.2 Single-Electron Transistor (SET) |
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208 | (3) |
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6.10 Molecular Electronics |
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211 | (5) |
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6.10.1 Molecular Switches and Memory Storage |
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215 | (1) |
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216 | (1) |
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Recommendations for Further Reading |
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216 | (3) |
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7 Nanoscale Heat Transfer |
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219 | (18) |
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7.1 Background: Hot Topic |
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219 | (1) |
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7.2 All Heat Is Nanoscale Heat |
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219 | (2) |
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7.2.1 Boltzmann's Constant |
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220 | (1) |
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221 | (9) |
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7.3.1 Thermal Conductivity of Nanoscale Structures |
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224 | (1) |
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7.3.1.1 Mean Free Path and Scattering of Heat Carriers |
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224 | (3) |
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7.3.1.2 Thermoelectrics: Better Energy Conversion with Nanostructures |
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227 | (2) |
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7.3.1.3 Quantum of Thermal Conduction |
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229 | (1) |
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230 | (2) |
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232 | (3) |
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7.5.1 Increased Radiation Heat Transfer: Mind the Gap! |
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232 | (3) |
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235 | (1) |
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Recommendations for Further Reading |
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236 | (1) |
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237 | (30) |
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8.1 Background: The Lycurgus Cup and the Birth of the Photon |
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237 | (1) |
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8.2 Photonic Properties of Nanomaterials |
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238 | (18) |
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238 | (2) |
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240 | (1) |
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240 | (1) |
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241 | (2) |
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8.2.4.1 Permittivity and the Free Electron Plasma |
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243 | (1) |
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8.2.4.2 Extinction Coefficient of Metal Particles |
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244 | (3) |
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8.2.4.3 Colors and Uses of Gold and Silver Particles |
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247 | (2) |
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249 | (1) |
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8.2.5.1 Tuning the Band Gap of Nanoscale Semiconductors |
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249 | (2) |
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8.2.5.2 Colors and Uses of Quantum Dots |
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251 | (3) |
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8.2.5.3 Lasers Based on Quantum Confinement |
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254 | (2) |
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256 | (6) |
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8.3.1 Limits of Light: Conventional Optics |
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257 | (2) |
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8.3.2 Near-Field Optical Microscopes |
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259 | (3) |
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262 | (1) |
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8.5 Photonic Crystals: A Band Gap for Photons |
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263 | (1) |
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264 | (1) |
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Recommendations for Further Reading |
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265 | (2) |
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9 Nanoscale Fluid Mechanics |
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267 | (30) |
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9.1 Background: Becoming Fluent in Fluids |
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267 | (5) |
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9.1.1 Treating a Fluid the Way It Should Be Treated: The Concept of a Continuum |
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267 | (2) |
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9.1.1.1 Fluid Motion, Continuum Style: The Navier-Stokes Equations |
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269 | (1) |
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9.1.1.2 Fluid Motion: Molecular Dynamics Style |
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270 | (2) |
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9.2 Fluids at the Nanoscale: Major Concepts |
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272 | (10) |
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9.2.1 Swimming in Molasses: Life at Low Reynolds Numbers |
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272 | (1) |
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273 | (2) |
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9.2.2 Surface Charges and the Electrical Double Layer |
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275 | (1) |
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9.2.2.1 Surface Charges at Interfaces |
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276 | (1) |
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9.2.2.2 Gouy-Chapman-Stern Model and Electrical Double Layer |
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276 | (3) |
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9.2.2.3 Electrokinetic Phenomena |
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279 | (1) |
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9.2.3 Small Particles in Small Flows: Molecular Diffusion |
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279 | (3) |
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9.3 How Fluids Flow at the Nanoscale |
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282 | (8) |
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282 | (1) |
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9.3.2 Ions and Macromolecules Moving through a Channel |
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283 | (3) |
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9.3.2.1 The Convection-Diffusion-Electromigration Equation: Nanochannel Electrophoresis |
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286 | (4) |
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9.3.2.2 Macromolecules in a Nanofluidic Channel |
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290 | (1) |
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9.4 Applications of Nanofluidics |
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290 | (3) |
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9.4.1 Analysis of Biomolecules: An End to Painful Doctor Visits? |
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291 | (2) |
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9.4.2 EO Pumps: Cooling Off Computer Chips |
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293 | (1) |
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293 | (1) |
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293 | (2) |
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Recommendations for Further Reading |
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295 | (2) |
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297 | (34) |
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10.1 Background: Our World in a Cell |
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297 | (2) |
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10.2 Introduction: How Biology Feels at the Nanometer Scale |
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299 | (6) |
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10.2.1 Biological Shapes at the Nanoscale: Carbon and Water Are the Essential Tools |
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299 | (2) |
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10.2.2 Inertia and Gravity Are Insignificant: The Swimming Bacterium |
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301 | (1) |
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10.2.3 Random Thermal Motion |
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302 | (3) |
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10.3 The Machinery of the Cell |
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305 | (22) |
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10.3.1 Sugars Are Used for Energy (but Also Structure) |
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306 | (1) |
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307 | (3) |
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10.3.2 Fatty Acids Are Used for Structure (but Also Energy) |
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310 | (2) |
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312 | (3) |
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10.3.3 Nucleotides Are Used to Store Information and Carry Chemical Energy |
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315 | (1) |
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10.3.3.1 Deoxyribonucleic Acid |
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315 | (5) |
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10.3.3.2 Adenosine Triphosphate |
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320 | (3) |
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10.3.4 Amino Acids Are Used to Make Proteins |
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323 | (1) |
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324 | (3) |
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10.4 Applications of Nanobiotechnology |
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327 | (2) |
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10.4.1 Biomimetic Nanostructures |
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328 | (1) |
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328 | (1) |
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329 | (1) |
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Recommendations for Further Reading |
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330 | (1) |
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331 | (18) |
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11.1 What Is Nanomedicine? |
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331 | (1) |
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11.2 Medical Nanoparticles |
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332 | (6) |
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332 | (3) |
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11.2.2 Lipid-Based Nanoparticles |
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335 | (2) |
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11.2.3 Polymer-Based Nanoparticles |
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337 | (1) |
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11.2.4 Drug Delivery Using Nanoparticles |
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337 | (1) |
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11.3 Nanomedicine and Cancer |
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338 | (2) |
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11.4 Biomimicry in Nanomedicine |
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340 | (4) |
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344 | (1) |
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11.6 Environmental Concerns |
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345 | (1) |
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11.7 Ethical Implications |
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346 | (1) |
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11.8 Commercial Exploration |
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346 | (1) |
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347 | (1) |
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Recommendations for Further Reading |
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347 | (2) |
Glossary |
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349 | (16) |
Index |
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365 | |