Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection.
Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease.
- Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules
- Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules
- Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells
- Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells
Arvustused
"...Volume 1 deals with numerous natural endogenous and exogenous (including animal, vegetal-, fungal-, bactericidal, and marine-derived molecules) while Volume 2 covers natural molecules of plant origin and how they could act as neuroprotective agents especially in neurodegenerative and neuroinflammatory diseases.... Renowned scientists experienced in research on the impact of natural molecules on health and disease have written all the chapters. The book has several colored illustrations which facilitate easy grasp of the subject. The book indeed covers vast knowledge in the field of natural molecules in neuroprotection and neurotoxicity. [ E]asy to understand,... a valuable resource on the subject written by well-known researchers from all over the world.... [ I]mmensely helpful,... quite unique." --©Doodys Review Service, 2024, Omer Iqbal, MD, FACC, FESC (Loyola University Medical Center)
Volume 1 Part I. Overview on Neuroprotection and Neurotoxicity
1.
Natural Molecules in Neuroprotection and Neurotoxicity in Neurodegenerative
Diseases Ines Moreno-Gonzalez, Ines Lopez del Castillo, Laura Vegas-Gomez and
Joana A. Loureiro
2. The Sea as a Source of Neuroprotective and other
Health-Protective Molecules
3. Can venoms be used in neuroprotection?
4.
Polyphenols-gut microbiota interplay in neuroprotection
5. Medical Potentials
of Natural Neuroprotectants Derived from Herbal Extracts and Their
Phytochemicals
6. Redox impairment in affective disorders and therapeutic
potential of phenolic bioactive
7. How the endoplasmic reticulum staggers
towards failure: New targets for neuroprotection
8. Modulation of
neuroinflammation by natural molecules
9. Epigenetic modulations induced by
natural molecules
10. Nutraceuticals and enteric glial cells
11. Natural
molecules in the treatment of schizophrenia
12. Anti-tumor effects induced by
natural molecules in the brain
13. Understanding the Neurogenic Potential of
Flavonoids and their Application for Neurodegenerative Diseases
14.
Transcriptomics in Neurotoxicity and Neuroprotection Part II. Neuroprotection
mediated by natural molecules Algae-derived Molecules
15. Neuroprotection
induced by Fucoxanthin
16. Phycocyanobilin Animal-derived Molecules
17. Bee
venom
18. Frog-derived peptides and neuroprotection
19. Snake venom
20.
Spider venom Human Endogenous Molecules
21. Acetyl-L-carnitine
22. Coenzyme
Q10
23. Creatine in neuroprotection and neurotoxicity
24. Neuroprotection
induced by erythropoietin
25. Neuroprotection by estrogens
26. Sex hormones
in neuroprotection and neurodegeneration
27. Melatonin
28. Neuroprotection
induced by neurotrophic factors
29. Neuroprotective Nucleosides
30. Taurine
Role in Neuroprotection Part III. Natural Molecules-associated
Nanotechnology-related Strategies Utilized in Neuroprotection
50.
Neuroprotection through Nanotechnology
51. Natural antioxidant nanoparticles
in neuroprotection
52. Nanomaterials-based approach in stroke
53.
Nanoparticles and the treatment of depression
54. Anti-tumor effects of
natural molecules in the brain: a nanotechnology-based approach Part IV.
Natural Molecules-associated Nanotechnology-related Strategies Utilized in
Neuroprotection
50. Neuroprotection through Nanotechnology
51. Natural
antioxidant nanoparticles in neuroprotection
52. Nanomaterials-based approach
in stroke
53. Nanoparticles and the treatment of depression
54. Anti-tumor
effects of natural molecules in the brain: a nanotechnology-based approach
Volume 2 Part I. Neuroprotection mediated by natural molecules Plant-derived
Molecules
1. Neuroprotection induced by agathisflavone
2. Alkaloids
3.
Andrographolide
4. Anthocyanins
5. Neuroprotection induced by apigenin
6.
Ascorbic acid
7. Neuroprotection induced by baicalein and baicalin
8.
Neuroprotection induced by biochanin A
9. Epigallocatechin gallate
10.
Carnosic Acid, mitochondria, and neuroprotection
11. Neuroprotection induced
by catechins in aging
12. Neuroprotection induced by chrysin
13. Citrus
Flavonoids - Mechanisms of neuorprotection and preclinical evidence
14.
Neuroprotection induced by coumarins in central nervous system disease models
15. Curcumin
16. Neuroprotection induced by dimethyl fumarate
17.
Neuroprotection induced by edible oils
18. Garlic components
19. Ginger
components
20. Green tea polyphenols for Neuroprotection: Effects against
Alzheimers and Parkinsons Diseases
21. Honey compounds
22. Neuroprotective
actions of hydroxytyrosol
23. Hydroxytyrosol: Focus on the
anti-neuroinflammatory action
24. Kaempferol
25. Neuroprotection induced by
lycopene
26. Neuroprotection induced by terpenes: focus on Alzheimer's
disease and Parkinson's disease
27. Olive oil components
28. Omega-3
polyunsaturated fatty acids
29. Neuroprotection induced by phloretin and
phloridzin
30. Phytomelatonin
31. Quercetin
32. Neuroprotection induced by
salvianolic acids
33. Sulforaphane
34. Effects of tocopherols and
tocotrienols on microglia-mediated neuroprotection
35. Vanillin Part II.
Neurotoxicity Induced by Natural Molecules: Animals and Humans Animal-derived
Molecules
43. Scorpion toxins
44. Anura-derived molecules from Pampa Biome
Human-endogenous Molecules
45. Cellular and molecular mechanisms of
ammonia-induced neurotoxicity: A neurotherapeutic prospect
46. Biliverdin and
bilirubin
47. Neurotoxicity induced by glycotoxins
48. Amyloids as endogenous
toxicants in neurodegenerative diseases
49. Neurotoxicity induced by lipid
metabolism associated endogenous toxicants
Marcos Roberto de Oliveira, PhD earned his bachelors degree in Biological Sciences at Federal University of Rio Grande do Sul (UFRGS) in 2005, followed by a masters and a Ph.D. in Biochemistry from the same institution. He is currently a professor and coordinates research at UFRGS. His research focuses on the neuroprotection mediated by natural molecules and involves studies on mitochondrial physiology, redox biology, bioenergetics, and inflammation in both in vitro and in vivo experimental models.
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