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E-raamat: Neuroscience in Space

  • Formaat: PDF+DRM
  • Sari: Engineering
  • Ilmumisaeg: 09-Jun-2010
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9780387789507
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  • Formaat: PDF+DRM
  • Sari: Engineering
  • Ilmumisaeg: 09-Jun-2010
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9780387789507

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This book offers an overview of neuroscience research performed in space since the observations made during the first manned space flights to the detailed scientific investigations currently being carried out onboard the International Space Station. This book is for the general scientific reader. Each project and the reason why it was done is described with illustrations, rationale and hypothesis, and a summary of results. Also, reference lists guide readers to the published papers from experiments. This book is a legacy of what we have learned on brain mechanisms and functions through research done in space, and a guide for what could be investigated in the future.

To be aware of the environment, one must sense or perceive that environment. The body senses the environment by the interaction of specialized sensory organs with some aspect or another of the environment. The central nervous system utilizes these sensations in order to coordinate and organize muscular movements, shift from uncomfortable positions, and adjust properly. One relevant question is “what is the relative contribution of gravity to these sensory and motor functions?”This book reviews the effects of space flight on the functioning of the sensory organs primarily used for balance and spatial orientation. Disorientation and malaise so frequently encountered during early exposure to microgravity and on return to Earth are described. Theories and actual data regarding the role of the central nervous system in the adaptation of sensory-motor functions (including the control of posture, eye movements, and self-orientation) to changing environmental gravity levels are explored. This book contains many illustrations, including photographs of equipment and experiments flown onboard space missions.

Arvustused

From the reviews:









"Clément present a comprehensive review of animal and human neuroscience research conducted either in space or with subjects who just returned from space. The information is presented with the detail that scientists require, clearly outlining the complicated issues involved in sending humans on brief and extended space journeys. Summing Up: Recommended. Graduate students through professionals." (D. K. Fry, Choice, Vol. 46 (7), March, 2009)



"The complexities of changes to the central and peripheral nervous systems as a result of space travel are described in great detail in this 322-page book . For those of you who are thinking that now may be a good time to move to Mars, there is a section (albeit short) on what to expect you get there. if you want a bit of diversion while still remaining in the neuroscience world, here is a book that many will find intriguing." (American Journal of Neuroradiology, Vol. 30, March, 2009)

Preface v
Space Neuroscience: What Is It?
1(32)
The Space Environment
2(4)
Microgravity
2(1)
Accelerations
3(2)
Light
5(1)
Ionizing Radiation
5(1)
Confinement and Isolation
5(1)
Opportunities for Space Research
6(5)
Space Missions in Low Earth Orbit
6(1)
Interplanetary Missions
7(1)
Moon Missions
7(2)
Mars Missions
9(2)
Ground-Based Facilities
11(1)
Neuroscience
11(2)
Definitions
11(2)
The Human Brain
13(1)
Effects of Gravity on Brain Functions
13(20)
Gravity-Sensing Receptors
14(2)
Central Processing
16(2)
Motor Responses
18(1)
Otolith Reflexes
18(2)
Posture
20(1)
Locomotion
20(1)
Arm Movements
21(1)
Spatial Orientation
21(1)
Definition
21(2)
Spatial Disorientation
23(1)
Effects of Space Flight
23(2)
Cognition
25(1)
Egocentric Localization
25(1)
Motor Imagery
26(1)
Anticipation
27(1)
Internal Representation
28(1)
Navigation
28(1)
Vestibular Cortex
29(1)
Integrative Physiology
30(1)
Conclusion
31(2)
History of Space Neuroscience
33(38)
A Brief History of Human Space Flight
33(4)
The Soviet and Russian Space Program
33(1)
The United States Space Program
34(3)
Additional Human Space Programs
37(1)
Space Flight: An Engineering and Scientific Marvel
37(3)
History of Neuroscience Research during Space Flight
40(3)
Humans in Space
40(2)
Space Life Sciences Experiments
42(1)
Neuroscience Experiments Conducted during Space Flight
43(28)
Operational Aspects
71(30)
Space Motion Sickness
72(14)
Signs and Symptoms
72(1)
Incidence
73(3)
Provocative Stimuli
76(1)
Head and Body Movements
76(1)
Orientation Cues
77(1)
Time Course
77(1)
Theories for Space Motion Sickness
78(1)
Fluid Shift Theory
79(1)
Sensory Conflict Theory
79(1)
Treisman's Theory
80(1)
Otolith Mass Asymmetry Hypothesis
80(2)
Sensory Compensation Hypothesis
82(1)
Otolith Tilt-Translation Reinterpretation Hypothesis
82(2)
Prediction
84(1)
Preflight Terrestrial Motion Sickness Susceptibility
85(1)
Preflight and Postflight Susceptibility
85(1)
In-Flight Susceptibility
85(1)
Sleep Disorders
86(3)
Causes for Sleep Disturbances during Space Flight
86(1)
Sleep Monitoring
87(2)
Behavior and Performance
89(7)
Factors for Impairment Behavior and Performance
90(1)
Effects of Space Flight on Operational Performance
91(2)
Effects of Space Flight on Cognitive and Psychomotor Functions
93(2)
Research Program
95(1)
Human Factors
96(2)
Summary
98(3)
Sensory Functions in Space
101(32)
Vision
102(3)
Hearing
105(2)
Taste and Olfaction
107(2)
Proprioception
109(5)
Limb Position and Pointing Ability
110(1)
Proprioceptive Illusions
111(3)
The Sense of Motion
114(8)
The Vestibular System
114(3)
Linear Acceleration and Gravity
117(2)
Effects of Microgravity on the Vestibular System
119(1)
Anatomical Studies
119(1)
Electrophysiological Studies
120(1)
Developmental Studies
121(1)
Perception Studies
122(9)
Motion Perception
123(3)
Tilt Perception
126(5)
Summary
131(2)
Posture, Movement and Locomotion
133(30)
Introduction
134(1)
In-Flight Posture Studies in Animals
135(2)
In-Flight Posture Studies in Humans
137(7)
Rest Posture
137(2)
In-Flight Postural Responses to Voluntary Movements
139(1)
Arm Raising and Tiptoe Raising
139(1)
Bending at the Waist
140(1)
Squatting
140(1)
In-Flight Postural Responses to Involuntary Movements
140(1)
Support Surface Translation
140(1)
Sudden Drop
141(2)
Muscle Vibration
143(1)
Pre-and Postflight Studies
144(8)
Rail Tests
144(1)
Stabilometry
145(1)
Moving Platform Tests
146(1)
Support Base Translation
146(1)
Support Base Rotation
147(1)
Complex Visual, Vestibular and Proprioceptive Tests
147(3)
Tests of Vestibulo-Spinal Reflexes
150(1)
Postural Responses to Voluntary Movements
150(1)
Clinical Benefits
151(1)
Locomotion Studies
152(8)
In-Flight Observation
152(1)
Pre- and Postflight Studies
153(1)
Head and Gaze Stability
153(2)
Dynamic Visual Acuity
155(1)
Lower Limb Kinematics
156(1)
Functional Mobility Test
157(1)
Walking on the Moon and Mars
158(2)
Summary
160(3)
Compensatory Eye Movements
163(26)
Caloric Nystagmus
164(1)
Vestibulo-Ocular Reflex
165(11)
Background
165(1)
VOR Asymmetry
166(1)
Effects of Gravity on VOR
167(1)
Microgravity Investigations
167(1)
Horizontal VOR
168(1)
Vertical VOR
169(2)
Torsional VOR
171(1)
Ocular Counter-Rolling
172(2)
Linear Acceleration
174(1)
Off-Vertical Axis Rotation
175(1)
Optokinetic System
176(5)
Background
176(1)
Microgravity Investigations
176(1)
Optokinetic Nystagmus
177(2)
Spatial Orientation of Eye Movements
179(2)
Gaze, Saccades and Smooth Pursuit
181(5)
Gaze Holding
181(1)
Orienting Gaze
182(2)
Target Acquisition
184(1)
Gaze Stabilization
184(2)
Smooth Pursuit
186(1)
Summary
186(3)
Spatial Orientation
189(44)
Introduction
190(3)
Maps and Internal Models
190(1)
Adaptive Effects
191(2)
Anecdotal Reports from Crewmembers
193(9)
Spontaneous Illusions
194(1)
Inversion Illusion
194(1)
Visual Reorientation Illusion
195(1)
Falling Sensation
196(1)
Oscillopsia
197(1)
Illusions Generated by Motion
198(1)
Input-Output Gain Disturbances
199(1)
Temporal Disturbances
200(1)
Path Disturbances
201(1)
Space Experiments on Spatial Orientation
202(9)
Subjective Horizontal and Vertical
202(2)
Visual Cues
204(1)
Otolith Cues
204(1)
Passive Head Movements
205(1)
Active Head MOvements
206(1)
Refinement of OTTR
206(4)
Proprioceptive Cues
210(1)
Tactile Cues
211(1)
Cognition in Space
211(20)
Behavior and Performance
212(1)
Navigation
213(3)
Mental Rotation
216(3)
Mental Representation
219(1)
Drawing and Handwriting Tests
220(4)
Depth Perception
224(4)
Distance Perception
228(3)
Summary
231(2)
Countermeasures
233(28)
What is a Countermeasure?
234(1)
Countermeasures for Space Motion Sickness
235(13)
Selection
236(1)
Vestibular Training
237(1)
Provocative Sensory Conflicts
237(3)
Biofeedback Training
240(2)
Pharmacological Countermeasures
242(1)
Ground-Based Studies
242(2)
SMS Medication during Space Flight
244(2)
Mechanical Countermeasures
246(1)
Pressurized Insoles
246(1)
Load Suits
247(1)
Pneumatic Occlusion Cuff and LBNP
247(1)
Neck Pneumatic Shock Absorber
247(1)
Electrical Devices
248(1)
Countermeasures for Behavior and Performance
248(4)
Intra-Vehicular Activity Training
248(1)
Extra-Vehicular Activity Training
249(2)
Psychological Training
251(1)
Artificial Gravity
252(5)
Summary
257(4)
A Vision for Space Neuroscience
261(22)
Basic Space Neuroscience Research
262(9)
Neuroscience Research on Board the ISS
262(1)
Time Course of Adaptation
263(3)
Tool for Space Neuroscience Research
266(1)
Integrative Physiology
266(1)
Critical Questions in Space Neuroscience
267(1)
Gravity-Sensing Receptors
267(1)
Motor Systems
268(1)
Spatial Orientation
269(2)
Cognition
271(1)
Applied Space Neuroscience Research
271(1)
Training
272(8)
Transit Earth-Mars
273(1)
Adaptation Procedures
274(1)
Reduced Dynamic Visual Acuity
275(1)
Size Distance Illusions
275(1)
Height Vertigo
276(1)
Mental Rotation
276(1)
Individual Differences
276(1)
Living on Mars
276(1)
Landing on Mars
276(1)
Effects of Long-Term Exposure to 0.38 g
277(3)
Returning to Earth
280(1)
Conclusion
280(3)
References 283(34)
Index 317
Since the first orbital flight of John Glenn, investigations have been conducted on the adaptation of nervous functions to space flight Millard Reschke and Gilles Clément have been active in this research, with experiments flown onboard Salyut, Mir, Spacelab, and 30+ flights of the Space Shuttle . This book presents in a readable text and detailed illustrations the findings from these experiments conducted during and after space missions. The authors also identify the neuroscience research that is foreseen onboard the International Space Station and what do we need to learn to understand fully the implications and risks in this area for a human mission to Mars.