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E-raamat: New Developments in Chromatin Research

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  • Formaat: 247 pages
  • Ilmumisaeg: 01-Apr-2017
  • Kirjastus: Nova Science Publishers Inc
  • ISBN-13: 9781620818329
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  • Formaat: 247 pages
  • Ilmumisaeg: 01-Apr-2017
  • Kirjastus: Nova Science Publishers Inc
  • ISBN-13: 9781620818329
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Chromatin is DNA plus the proteins (and RNA) that package DNA within the cell nucleus. The primary functions of chromatin are: to package DNA into a smaller volume to fit in the cell, to strengthen the DNA to allow mitosis and meiosis and prevent DNA damage, and to control gene expression and DNA replication. In this book, the authors present topical research in the study of chromatin including the varied functions of aurora kinases A and B in mitosis and carcinogenesis; the chromatin state of pluripotent stem cells; MITF meets chromatin in melanoma; the state of chromatin as an integrative indicator of cell stress; analyzing DNA damage and its repair throughout entire genomes; the cloning process, structural characterization of Revolver transposon and its patented application for chromosome tags; DNA damage and Rad16; and glucocorticoid-induced chromatin remodeling.
Preface vii
Chapter 1 The Varied Functions of Aurora Kinases A and B in Mitosis and Carcinogenesis
1(28)
Jyoti Iyer
Saili Moghe
Niveditha Rajagopalan
Manabu Furukawa
Ming-Ying Tsai
Chapter 2 New Developments in Chromatin Research: An Epigenetic Perspective
29(30)
Vichithra R. B. Liyanage
Robby M. Zachariah
Genevive P. Delcuve
James R. Davie
Mojgan Rastegar
Chapter 3 Sperm Chromatin Integrity, DNA Fragmentation and Male Fertility
59(24)
Maria Enciso
Dagan Wells
Chapter 4 The Chromatin State of Pluripotent Stem Cells
83(22)
Mehdi Shafa
Derrick E. Rancourt
Chapter 5 MITF Meets Chromatin in Melanoma
105(18)
Jiri Vachtenheim
Lubica Ondrusova
Chapter 6 The State of Chromatin as an Integrative Indicator of Cell Stress
123(22)
Yuriy Shckorbatov
Chapter 7 A Genomics Approach to Analysing DNA Damage and Its Repair throughout Entire Genomes
145(16)
Yumin Teng
Mark Bennett
Katie E. Evans
Huayun Zhuang-Jackson
Andy Higgs
Simon H. Reed
Raymond Waters
Chapter 8 Recent Patent on Revolver-2: A Novel Transposon-Like Gene Useful for Chromosome Tags of Rye
161(16)
Motonori Tomita
Chapter 9 The Removal of DNA Damage Is Promoted by the Yeast Global Genome Nucleotide Excision Repair Factor Rad16
177(18)
Shirong Yu
Yumin Teng
Raymond Waters
Simon Reed
Chapter 10 Chromatin Condensation in Infertile Sperm
195(16)
Sirikul Manochantr
Chapter 11 Glucocorticoid-Induced Chromatin Remodeling: A Novel Molecular Mechanism of Traumatic Stress
211(12)
Lei Zhang
He Li
Xian-Zhang Hu
Xiao Xia Li
Stanley Smerin
Robert Ursano
Index 223