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E-raamat: New Techniques for Studying Biomembranes

Edited by (Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, USA)
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New Techniques for Studying Biomembranes describes some of the latest methods used to investigate the dynamic distribution of specific lipids in membranes and their effects on other membrane components. The contributors present important discoveries with respect to lipid analysis and lipid interactions with membrane proteins. Various methods, which have been used to study lipid bilayer structure and lipid organization in membranes, include both in vitro and in vivo membrane systems, and study membrane proteins in various membrane systems.

Key Features:











Reviews both in vivo and in vitro analytical technologies and methods for studying membrane structure and function





Explores how lipid bilayers and membrane proteins interact





Includes contributions from an international team of researchers actively studying membrane structure and function





Identifies various diseases whose causes are related to membrane proteins

Related Titles:

Christopher R. Jacobs, Hayden Huang, and Ronald Y. Kwon. Introduction to Cell Mechanics and Mechanobiology (ISBN 978-0-8153-4425-4)

Wendell Lim and Bruce Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1)

Stephen Rothman. Proteins Crossing Membranes: A Scientists Memoir (978-0-3670-7449-4)

Arvustused

"Each chapter begins with an introduction that carefully covers the fundamental operating principles of each method illuminated by details of its historical development. This extends to the mathematical functions encountered in the chapters on scanning angle interference microscopy and the analysis of protein function in reconstituted membrane systems. Each chapter appears to be well illustrated and thoroughly referenced. The end result is a concise and straightforward introduction to the topics selected for each chapter." - Peter J. Kennelly, PhD(Virginia Tech)

Preface vii
Editor ix
Contributors xi
Chapter 1 Introduction: New Tools for Challenges in Membrane Biology
1(8)
Qiu-Xing Jiang
Chapter 2 Lipidomics in Human Cancer and Malnutrition
9(16)
Iqbal Mahmud
Timothy J. Garrett
Chapter 3 Tracking and Imaging: SERS Characterization of Biomembranes
25(14)
Wen Ren
Joseph Irudayaraj
Chapter 4 Scanning Angle Interference Microscopy (SAIM): Theory, Acquisition, Analysis and Biological Applications
39(24)
Cristina Bertocchi
Timothy J. Rudge
Andrea Ravasio
Chapter 5 Atomic Force Microscopy of Biomembranes: A Tool for Studying the Dynamic Behavior of Membrane Proteins
63(30)
Yi Ruan
Lorena Redondo-Morata
Simon Scheuring
Chapter 6 Reconstituted Membrane Systems for Assaying Membrane Proteins in Controlled Lipid Environments
93(30)
Gaya P. Yadav
Qiu-Xing Jiang
Chapter 7 Cholesterol Modulation of BK (MaxiK; Slol) Channels: Mechanistic and Pharmacological Aspects
123(22)
Alex M. Dopico
Anna N. Bukiya
Kelsey North
Chapter 8 Restoration of Membrane Environments for Membrane Proteins for Structural and Functional Studies
145(16)
Liguo Wang
Index 161
Qiu-Xing Jiang is faculty in the Department of Microbiology and Cell Science and and Electron Microscopy Faculty Director at the University of Florida's Interdisciplinary Center for Biotechnology Research. His laboratory is working in two areas. One is the structural and functional studies of membrane proteins and intracellular signaling complexes. The second general direction is the development of new techniques for both single particle cryoEM and for studying eukaryotic membrane proteins in lipid environments.
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