Although nitric oxide (NO) is an important biological signaling molecule, its free-radical electronic configuration makes it a most reactive molecule and the scariest colorless gas causing immense environmental and health hazards. Detection of NO levels in biological samples and in the atmosphere is therefore crucial. In the past few years, extensive efforts have been devoted to developing many active sensors and effective devices for detecting and quantifying atmospheric NO, NO generated in biological samples, and NO exhaled in the human breath.
This book provides a concrete summary of recent state-of-the-art small-molecule probes and novel carbon nanomaterials used for chemical, photoluminescent, and electrochemical NO detection. One chapter is especially dedicated to the available devices used for detecting NO in the human breath that indirectly infers to lung inflammation. The authors with expertise in diverse dimensions have attempted to cover almost all areas of NO sensing.
| Preface |
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vii | |
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1 | (6) |
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2 Small-Molecule and Metal Complexes as Nitric Oxide Sensors |
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7 | (36) |
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7 | (3) |
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2.2 Nitric Oxide Homeostasis |
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10 | (2) |
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2.3 Fluorescent Detection Kit for NO Sensors |
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12 | (1) |
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2.3.1 Different Strategies |
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12 | (1) |
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2.3.2 Fluorophore Displacement without Metal Reduction |
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13 | (1) |
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2.3.3 Metal Reduction without Fluorophore Displacement |
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13 | (1) |
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2.3.4 Metal Reduction with Fluorophore Displacement |
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13 | (1) |
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2.4 Metal Complexes for NO Sensing |
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13 | (14) |
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13 | (5) |
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18 | (1) |
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2.4.3 Reversible NO Sensing by Rhodium Complexes |
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19 | (1) |
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2.4.4 NO Detection with Ruthenium Complexes |
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20 | (3) |
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2.4.5 Copper Complex as a NO Sensing Probe |
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23 | (2) |
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2.4.6 Copper (II) Conjugate Polymer |
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25 | (1) |
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2.4.7 Copper (II) Anthracyl Cyclam Complex |
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26 | (1) |
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2.5 Polymer-Based Sensors |
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27 | (5) |
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2.6 Biomedical Applications |
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32 | (5) |
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37 | (6) |
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3 Nitric Oxide Sensing with Carbon Nanomaterials |
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43 | (36) |
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43 | (1) |
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3.2 Nitric Oxide Sensing with Carbon Dots |
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44 | (7) |
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3.3 Nitric Oxide Sensing with Carbon Nanotubes |
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51 | (7) |
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3.4 Nitric Oxide Sensing with Graphene |
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58 | (14) |
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72 | (7) |
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4 Electrochemical Nitric Oxide Detection |
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79 | (38) |
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79 | (3) |
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4.2 Scope of Electrodes for NO Detection |
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82 | (5) |
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4.3 NO Detection on Noble Metals and Pt Electrodes |
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87 | (4) |
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4.4 Biosensors with Modified Electrodes |
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91 | (6) |
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4.5 Metallocycle-Modified Electrodes |
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97 | (5) |
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4.6 Nanocomposite Electrodes |
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102 | (5) |
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107 | (10) |
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5 Nitric Oxide--Sensing Devices: A Practical Application |
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117 | (20) |
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117 | (1) |
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5.2 Devices for Exhaled NO Detection |
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118 | (12) |
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5.2.1 Chemiluminiscence Devices |
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118 | (3) |
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5.2.2 Electrochemical Devices |
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121 | (3) |
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124 | (6) |
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5.3 In Vivo NO Measurement Devices |
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130 | (2) |
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132 | (5) |
| Index |
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137 | |
Sagarika Bhattacharya is a postdoctoral fellow at Ben Gurion University of the Negev, Israel. She obtained her PhD in chemistry from the University of Calcutta, India. Her current research interest is the use of carbon nanodot gel for biosensing and optics.
Subhra Samanta is a DST Inspire faculty in the CSIR-Central Mechanical Engineering Research Institute, India. He obtained his PhD in bioinorganic chemistry from the Indian Association for the Cultivation of Sciences, India. His current research interest is the mechanism underlying nitric oxide reductase, clean energy conversion, and biowaste management.
Biswarup Chakraborty is assistant professor at the Department of Chemistry, Indian Institute of Technology Delhi, India. He obtained his PhD in chemistry from the Indian Association for the Cultivation of Science, with a specialization in bioinorganic chemistry. His current research interest is the design of photo(electro)catalysts for energy harvesting and storage applications.
Lisainfo e-raamatute kohta