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E-raamat: Nolte's The Human Brain E-Book: Nolte's The Human Brain E-Book

(Regents Professor and Head, Department of Pharmacology, Co-Director of the MD/PhD Program, University of Arizona, Tucson, Arizona, USA), (Distinguished Professor and Chair, Department of Foundational Medical Studies, Oakland University)
  • Formaat: PDF+DRM
  • Ilmumisaeg: 05-Feb-2020
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323755306
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  • Formaat: PDF+DRM
  • Ilmumisaeg: 05-Feb-2020
  • Kirjastus: Elsevier - Health Sciences Division
  • Keel: eng
  • ISBN-13: 9780323755306
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Throughout seven popular editions, Nolte's The Human Brain has accomplished the challenging task of demystifying the complexities of the gross anatomy of the brain, spinal cord, and brainstem. A clear writing style, interesting examples, and high-quality visual cues bring this complicated subject to life and make it more understandable and enjoyable to learn. You'll get the depth of coverage you need with a well-rounded presentation of all key topics in functional neuroanatomy and neuroscience.

  • Features highly templated, concise chapters that reinforce and expand your knowledge.
  • Provides a real-life perspective through clinically relevant examples, up-to-date neuroimaging techniques, and superb illustrations that support and explain the text.
  • Features a glossary of key terms that elucidates every part of the text, complimented by 3-dimensional images of the brain and the most up-to-date terminology throughout.
  • Helps you gauge your mastery of the material and build confidence with over 100 multiple choice questions available online that provide effective chapter review and quick practice for your exams.
  • New!
  • Clinical Focus Boxes, including neuropathology and neuropharmacology.
  • New!
  • Integrated coverage of neurogenetics and neuroimmunology.
  • Enhanced eBook version included with purchase.
  • Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Arvustused

"This book is an engaging overview of the human brain. Its focus is to provide readers with all the foundational knowledge needed to explore neuroanatomy and, in many instances, neurophysiology with greater focus."

-Magdalena Muchlinski, Masters/Doctorate (MA; PhD) (Oregon Health and Science University) Doody's Review Service

1 Introduction to the Nervous System
1(36)
The Nervous System Has Central and Peripheral Parts
1(1)
The Principal Cellular Elements of the Nervous System Are Neurons and Glial Cells
1(36)
2 Development of the Nervous System
37(18)
The Neural Tube Gives Rise to the Central Nervous System
37(9)
The Neural Crest and Cranial Placodes Give Rise to the Peripheral Nervous System
46(1)
Adverse Events During Development Can Cause Congenital Malformations of the Nervous System
47(8)
3 Gross Anatomy and General Organization of the Central Nervous System
55(26)
The Long Axis of the CNS Bends at the Cephalic Flexure
55(1)
Hemisecting a Brain Reveals Parts of the Diencephalon, Brainstem, and Ventricular System
56(1)
Humans, Relative to Other Animals, Have Large Brains and Many Neurons
57(1)
Named Sulci and Gyri Cover the Cerebral Surface
58(7)
The Diencephalon Includes the Thalamus and Hypothalamus
65(1)
Most Cranial Nerves Are Attached to the Brainstem
66(2)
The Cerebellum Includes a Vermis and Two Hemispheres
68(1)
Sections of the Forebrain Reveal the Basal Nuclei and Limbic Structures
69(1)
Parts of the Nervous System Are Interconnected in Systematic Ways (Generalizations)
70(11)
4 Meningeal Coverings of the Brain and Spinal Cord
81(18)
There Are Three Meningeal Layers: The Dura Mater, Arachnoid, and Pia Mater
81(1)
The Dura Mater Provides Mechanical Strength
81(5)
The Arachnoid Mater
86(2)
Pia Mater Covers the Surface of the CNS
88(1)
Lymphatics of the CNS
89(1)
The Vertebral Canal Contains a Spinal Epidural Space
90(1)
Bleeding Can Open Up Potential Meningeal Spaces
90(1)
Parts of the CNS Can Herniate From One Intracranial Compartment Into Another
91(8)
5 Ventricles and Cerebrospinal Fluid
99(20)
The Brain Contains Four Ventricles
99(3)
Choroid Plexus Is the Source of Most CSF
102(4)
Imaging Techniques Allow Noninvasive Visualization of the CNS
106(6)
Disruption of CSF Circulation Can Cause Hydrocephalus
112(7)
6 Blood Supply of the Brain
119(28)
The Internal Carotid Arteries and Vertebral Arteries Supply the Brain
119(10)
Imaging Techniques Allow Arteries and Veins to Be Visualized
129(1)
Blood Flow to the CNS Is Closely Controlled
129(8)
A System of Barriers Partially Separates the Nervous System From the Rest of the Body
137(2)
Superficial and Deep Veins Drain the Brain
139(8)
7 Electrical Signaling by Neurons
147(26)
A Lipid-Protein Membrane Separates Intracellular and Extracellular Fluids
148(5)
Inputs to Neurons Cause Slow, Local Potential Changes
153(3)
Action Potentials Convey Information Over Long Distances
156(10)
Resistors, Capacitors, and Neuronal Membranes
166(3)
Calculating the Membrane Potential
169(4)
8 Synaptic Transmission Between Neurons
173(23)
There Are Five Steps in Conventional Chemical Synaptic Transmission
174(4)
Synaptic Transmission Can Be Rapid and Point-to-Point, or Slow and Often Diffuse
178(4)
Synaptic Strength Can Be Facilitated or Depressed
182(3)
Most Neurotransmitters Are Small Amine Molecules, Amino Acids, or Neuropeptides
185(5)
Gap Junctions Mediate Direct Current Flow From One Neuron to Another
190(6)
9 Sensory Receptors and the Peripheral Nervous System
196(25)
Receptors Encode the Nature, Location, Intensity, and Duration of Stimuli
196(5)
Somatosensory Receptors Detect Mechanical, Chemical, or Thermal Changes
201(14)
Peripheral Nerves Convey Information to and From the CNS
215(6)
10 Spinal Cord
221(37)
The Spinal Cord Is Segmented
221(5)
All Levels of the Spinal Cord Have a Similar Cross-Sectional Structure
226(2)
The Spinal Cord Is Involved in Sensory Processing, Motor Outflow, and Reflexes
228(1)
Spinal Gray Matter Is Regionally Specialized
228(3)
Reflex Circuitry Is Built Into the Spinal Cord
231(3)
Ascending and Descending Pathways Have Defined Locations in the Spinal White Matter
234(12)
The Autonomic Nervous System Monitors and Controls Visceral Activity
246(4)
A Longitudinal Network of Arteries Supplies the Spinal Cord
250(1)
Spinal Cord Damage Causes Predictable Deficits
251(7)
11 Organization of the Brainstem
258(28)
The Brainstem Has Conduit, Cranial Nerve, and Integrative Functions
258(1)
The Medulla, Pons, and Midbrain Have Characteristic Gross Anatomical Features
259(3)
The Internal Structure of the Brainstem Reflects Surface Features and the Position of Long Tracts
262(7)
The Reticular Core of the Brainstem Is Involved in Multiple Functions
269(6)
Some Brainstem Nuclei Have Distinctive Neurochemical Signatures
275(3)
The Brainstem Is Supplied by the Vertebral-Basilar System
278(8)
12 Cranial Nerves and Their Nuclei
286(26)
Cranial Nerve Nuclei Have a Generally Predictable Arrangement
286(2)
Cranial Nerves III, IV, VI, XI, and XII Contain Somatic Motor Fibers
288(8)
Branchiomeric Nerves Contain Axons From Multiple Categories
296(16)
13 The Chemical Senses of Taste and Smell
312(16)
The Perception of Flavor Involves Gustatory, Olfactory, Trigeminal, and Other Inputs
312(1)
Taste Is Mediated by Receptors in Taste Buds Innervated by Cranial Nerves VII, IX, and X
313(5)
Olfaction Is Mediated by Receptors That Project Directly to the Telencephalon
318(10)
14 Hearing and Balance: The Eighth Cranial Nerve
328(34)
Auditory and Vestibular Receptor Cells Are Located in the Walls of the Membranous Labyrinth
328(6)
The Cochlear Division of the Eighth Nerve Conveys Information About Sound
334(13)
The Vestibular Division of the Eighth Nerve Conveys Information About Linear and Angular Acceleration of the Head
347(12)
Position Sense Is Mediated by the Vestibular, Proprioceptive, and Visual Systems Acting Together
359(3)
15 Atlas of the Human Brainstem
362(10)
16 The Thalamus and Internal Capsule: Getting to and From the Cerebral Cortex
372(24)
The Diencephalon Includes the Epithalamus, Subthalamus, Hypothalamus, and Thalamus
372(3)
The Thalamus Is the Gateway to the Cerebral Cortex
375(13)
Interconnections Between the Cerebral Cortex and Subcortical Structures Travel Through the Internal Capsule
388(8)
17 The Visual System
396(39)
The Eye Has Three Concentric Tissue Layers and a Lens
396(4)
The Retina Contains Five Major Neuronal Cell Types
400(6)
Retinal Neurons Translate Patterns of Light Into Patterns of Contrast
406(12)
Half of the Visual Field of Each Eye Is Mapped Systematically in the Contralateral Cerebral Hemisphere
418(8)
Primary Visual Cortex Sorts Visual Information and Distributes It to Other Cortical Areas
426(3)
Early Experience Has Permanent Effects on the Visual System
429(1)
Reflex Circuits Adjust the Size of the Pupil and the Focal Length of the Lens
430(5)
18 Overview of Motor Systems
435(15)
Each Lower Motor Neuron Innervates a Group of Muscle Fibers, Forming a Motor Unit
435(2)
Motor Control Systems Involve Both Hierarchical and Parallel Connections
437(4)
The Corticospinal Tract Has Multiple Origins and Terminations
441(9)
19 Basal Nuclei
450(19)
The Basal Nuclei Include Five Major Groups of Cells
450(4)
Basal Nuclei Circuitry Involves Multiple Parallel Loops That Modulate Cortical Output
454(1)
Interconnections of the Basal Nuclei Determine the Pattern of Their Outputs
455(7)
Perforating Branches From the Cerebral Arterial Circle (of Willis) Supply the Basal Nuclei
462(1)
Many Basal Nuclei Disorders Result in Abnormalities of Movement
462(7)
20 Cerebellum
469(28)
The Cerebellum Can Be Divided Into Both Transverse and Longitudinal Zones
469(11)
Cerebellar Cortex Receives Multiple Inputs
480(4)
Each Longitudinal Zone Has a Distinctive Output
484(6)
Clinical Syndromes Correspond to Functional Zones
490(7)
21 Eye Movements
497(16)
Six Extraocular Muscles Move the Eye in the Orbit
497(3)
There Are Fast and Slow Conjugate Eye Movements
500(6)
Changes in Object Distance Require Vergence Movements
506(2)
The Basal Nuclei and Cerebellum Participate in Eye Movement Control
508(5)
22 Cerebral Cortex
513(36)
Most Cerebral Cortex Is Neocortex
513(7)
Neocortical Areas Are Specialized for Different Functions
520(17)
The Corpus Callosum Unites the Two Cerebral Hemispheres
537(3)
Consciousness and Sleep Are Active Processes
540(9)
23 Drives and Emotions: The Hypothalamus and Limbic System
549(25)
The Hypothalamus Coordinates Drive-Related Behaviors
549(13)
Limbic Structures Are Interposed Between the Hypothalamus and Neocortex
562(12)
24 Formation, Modification, and Repair of Neuronal Connections
574(26)
Both Neurons and Connections Are Produced in Excess During Development
574(5)
Synaptic Connections Are Adjusted Throughout Life
579(14)
PNS Repair Is More Effective Than CNS Repair
593(7)
25 Atlas of the Human Forebrain
600(20)
Glossary 620(19)
Index 639
Todd W. Vanderah is Regents Professor and Head, Department of Pharmacology, Co-Director of the MD/PhD Program at the University of Arizona, Tucson, Arizona. Douglas J. Gould is Distinguished Professor and Chair in the Department of Foundational Medical Studies, Oakland University William Beaumont School of Medicine, Rochester, Michigan.