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E-raamat: Ophthalmic Epidemiology: Current Concepts to Digital Strategies

Edited by (Duke-NUS Medical School, Singapore), Edited by (Duke-NUS Medical School, Singapore)
  • Formaat: 300 pages
  • Ilmumisaeg: 24-May-2022
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351378789
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Ophthalmic Epidemiology: Current Concepts to Digital StrategiesSuurem pilt
  • Formaat: 300 pages
  • Ilmumisaeg: 24-May-2022
  • Kirjastus: CRC Press
  • Keel: eng
  • ISBN-13: 9781351378789
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Ophthalmic Epidemiology: Current Concepts to Digital Strategies provides a comprehensive guide to graduate students, ophthalmologists, and researchers in ophthalmic epidemiology. It covers recently developed new methodologies, technologies and resources in ocular epidemiological research, such as telemedicine, disease registries, EMR, bio-banks and omics. This book also summarizes recent epidemiological findings and provides up-to-date data on ocular diseases. Furthermore, it introduces and discusses the uses of epidemiology in the evaluation of health services and population screening programs and reviews the application of epidemiology in intervention trials in the communities.

Key Features

  • Comprehensive guide to the epidemiology of common eye diseases.

  • Provides updates on the prevalence and risk factors of eye diseases.

    • Outlines how epidemiological techniques can be utilized to evaluate ophthalmic health services and programs.



    • This book provides a comprehensive guide to graduate students, ophthalmologists, and researchers in ophthalmic epidemiology. It covers recently developed new methodologies, technologies and resources in ocular epidemiological research, such as telemedicine, disease registries, EMR, bio-banks and omics.

    Arvustused

    This book broadly covers ophthalmic epidemiology. The first half of the book covers several key technologies and strategies in modern ophthalmic epidemiology while the second half discusses current epidemiologic data for many different major eye diseases. Overall, the book is very organized and each chapter is broken into an appropriate number of subsections of discussion.There are a good number of tables and figures included throughout the book.

    -- Emily M Witsberger, MD, University of Iowa Hospitals and Clinics

    Preface x
    About the Editors xi
    List of Contributors
    		xii
    Part I Current and Future Epidemiological Approaches to Ophthalmology
    		1(84)
    1 Use of Electronic Health Records, Disease Registries, and Health Insurance Databases in Ophthalmology
    		3(11)
    Rachel Marjorie Wei Wen Tseng
    Grace May Chuang
    Zhi Da Soh
    Yih-Chung Tham
    1.1 Background
    		3(1)
    1.2 Electronic Health Records and Disease Registries
    		3(5)
    1.3 Health Insurance Databases
    		8(3)
    1.4 Future Outlook and Challenges
    		11(1)
    1.5 Conclusion
    		11(3)
    2 Application of Mobile and Wearable Technology in Data Collection for Ophthalmology
    		14(9)
    Ashwin Venkatesh
    Pradeep Ramulu
    2.1 Overview of General Use Cases of Remote Monitoring
    		14(1)
    2.2 Domains of Remote Measurements
    		14(6)
    2.3 Conclusion
    		20(3)
    3 Telemedicine in Ophthalmology
    		23(18)
    Jane Scheetz
    Samantha Simkin
    Zachary Tan
    Shuan Dai
    Mingguang He
    3.1 Telemedicine
    		23(3)
    3.2 Diabetic Retinopathy Background
    		26(5)
    3.3 Retinopathy of Prematurity Background
    		31(6)
    3.4 Conclusion
    		37(4)
    4 Biochemical Markers in Ophthalmology
    		41(21)
    Abdus Samad Ansari
    Pirro G. Hysi
    4.1 Introduction
    		41(1)
    4.2 Genomic Markers in Ophthalmology
    		41(6)
    4.3 Epigenetic and Transcription Regulation Biomarkers and Ocular Disease Phenotypes
    		47(3)
    4.4 Small Molecules and Proteins in Ophthalmology
    		50(2)
    4.5 Proteomics
    		52(2)
    4.6 Microbiome and Human Disease
    		54(8)
    5 Statistical Methods for Big Data
    		62(13)
    Emmanuel Kernel
    Alexandre Thiery
    Simon Nusinovici
    5.1 Introduction
    		62(1)
    5.2 Fundamental Notions of Statistical Modeling
    		62(2)
    5.3 The Main Machine Learning Models
    		64(6)
    5.4 Examples of Statistical Methods in Big Data
    		70(2)
    5.5 Conclusion
    		72(3)
    6 Common Statistical Issues in Ophthalmic Research
    		75(10)
    Catey Bunce
    Gabriela Czanner
    6.1 Introduction
    		75(1)
    6.2 What Is Statistics and Why Do We Use It?
    		76(1)
    6.3 Common Issues in Inferential Statistical Methods
    		77(5)
    6.4 Common Issues in Descriptive Statistical Methods
    		82(1)
    6.5 Summary
    		83(2)
    Part II Updates on Epidemiology of Eye Diseases
    		85(146)
    7 Refractive Errors, Myopia, and Presbyopia
    		87(26)
    Ka Wai Kam
    Chi Pui Pang
    Jason C. S. Yam
    7.1 Introduction
    		87(1)
    7.2 Myopia
    		87(12)
    7.3 Astigmatism
    		99(1)
    7.4 Hyperopia
    		100(3)
    7.5 Presbyopia
    		103(2)
    7.6 Conclusion
    		105(8)
    8 Corneal Disorders
    		113(15)
    Darren S. J. Ting
    Rashmi Deshmukh
    Daniel S. W. Ting
    Marcus Ang
    8.1 Introduction
    		113(1)
    8.2 Epidemiology of Corneal Blindness
    		113(3)
    8.3 Big Data for Corneal Diseases
    		116(5)
    8.4 Future Technologies for Corneal Diseases
    		121(1)
    8.5 Conclusion
    		122(6)
    9 Dry-Eye Disease
    		128(6)
    Fiona Stapleton
    Revathy Mani
    9.1 Introduction
    		128(1)
    9.2 Burden, Cost, and Impact of Dry-Eye Disease
    		128(2)
    9.3 Risk Factors for Dry-Eye Disease
    		130(1)
    9.4 Conclusion
    		131(3)
    10 Cataract and Cataract Surgical Coverage
    		134(12)
    Olusola Olawoye
    Priya Adhisesha Reddy
    Ving Fai Chan
    Prabhath Piyasena
    Nathan Congdon
    10.1 Introduction
    		134(1)
    10.2 Age-Related Cataracts
    		134(1)
    10.3 Congenital Cataract
    		135(1)
    10.4 Cataract-Grading Methods
    		136(3)
    10.5 Cataract Surgical Coverage and Its Measurement
    		139(1)
    10.6 Community Intervention Programs to Increase Cataract Surgical Coverage
    		140(1)
    10.7 Conclusion
    		141(5)
    11 Glaucoma
    		146(20)
    Zhi Da Soh
    Victor Koh
    Ching-Yu Cheng
    11.1 Introduction
    		146(1)
    11.2 Glaucoma Classification
    		146(1)
    11.3 Global Prevalence of Glaucoma
    		146(4)
    11.4 Incidence of Primary Glaucoma
    		150(1)
    11.5 Undetected Glaucoma
    		151(2)
    11.6 Impact of Glaucoma
    		153(1)
    11.7 Risk Factors of Primary Glaucoma
    		154(3)
    11.8 Glaucoma Screening
    		157(1)
    11.9 Future Directions
    		158(1)
    11.10 Conclusion
    		158(8)
    12 Age-Related Macular Degeneration
    		166(7)
    Jost B. Jonas
    Songhomitra Panda-Jonas
    12.1 Introduction
    		166(1)
    12.2 Prevalence of AMD
    		166(1)
    12.3 Visual Impairment and Blindness Caused by AMD
    		166(2)
    12.4 Risk Factors of AMD
    		168(1)
    12.5 Limitations of Current Population-Based Studies and Future Works
    		169(1)
    12.6 Conclusions
    		169(4)
    13 Polypoidal Choroidal Vasculopathy
    		173(12)
    Shinji Ono
    Yasuo Yanagi
    13.1 Introduction
    		173(1)
    13.2 Definition of PCV
    		173(2)
    13.3 Pathogenesis of PCV
    		175(1)
    13.4 Epidemiology of PCV
    		175(3)
    13.5 Genetics of PCV
    		178(1)
    13.6 Randomized Controlled Trials and Real-World Data
    		179(2)
    13.7 New Technologies in Epidemiological Research of PCV
    		181(4)
    14 Diabetic Retinopathy
    		185(10)
    Charumathi Sabanayagam
    Tien Yin Wong
    14.1 Introduction
    		185(1)
    14.2 Classification of DR
    		185(1)
    14.3 Epidemiology and Impact of DR
    		185(4)
    14.4 Prevention of DR
    		189(2)
    14.5 DR Screening for Detecting Onset and Monitoring Progression of DR
    		191(1)
    14.6 Conclusion
    		191(4)
    15 Non-DR Retinal Vascular Diseases
    		195(13)
    Sobha Sivaprasad
    Luke Nicholson
    Shruti Chandra
    15.1 Introduction
    		195(1)
    15.2 Retinal Vein Occlusion
    		195(1)
    15.3 Hypertensive Retinopathy
    		196(2)
    15.4 Retinal Arterial Occlusion
    		198(3)
    15.5 Ocular Ischemic Syndrome
    		201(7)
    16 Uveitis
    		208(10)
    De-Kuang Hwang
    Yih-Shiou Hwang
    16.1 Introduction
    		208(1)
    16.2 Epidemiology of Uveitis
    		209(4)
    16.3 Conditions in Specific Disease Entities
    		213(1)
    16.4 Conclusion
    		214(4)
    17 Ocular Tumors
    		218(13)
    Vishal Raval
    Alexander Melendez
    Hansell Soto
    Allexya Affonso
    Rubens Belfort Neto
    Arun D. Singh
    17.1 Introduction
    		218(1)
    17.2 Retinoblastoma
    		218(3)
    17.3 Uveal Melanoma
    		221(4)
    17.4 Conjunctival Squamous Cell Carcinoma
    		225(6)
    Part III Epidemiological Methods for Evaluation and Intervention
    		231(44)
    18 Systematic Review and Meta-Analysis
    		233(9)
    Gianni Virgili
    Jennifer Evans
    Tianjing Li
    18.1 Introduction
    		233(1)
    18.2 Steps in Completing a Systematic Review of Interventions
    		233(2)
    18.3 Systematic Reviews of Other Types of Research Questions
    		235(3)
    18.4 A Database of Systematic Reviews
    		238(1)
    18.5 Conclusions
    		239(3)
    19 Assessment of Vision-Related Quality of Life
    		242(13)
    Eva K. Fenwick
    Preeti Gupta
    Ryan E. K. Man
    19.1 Introduction
    		242(1)
    19.2 Measurement of Patient-Reported Outcomes
    		242(1)
    19.3 Systematic Review of the VRQoL Impact of VI and Ocular Pathologies at a Population-Based Level
    		243(3)
    19.4 What Are the Best VRQoL PROMs to Use in Ocular Epidemiology?
    		246(3)
    19.5 Conclusions and Future Research
    		249(6)
    20 Screening Programs
    		255(11)
    Jakob Grauslund
    Malin Lundberg Rasmussen
    20.1 Introduction
    		255(1)
    20.2 Conceptualizing Screening
    		255(1)
    20.3 Screening Programs in Ophthalmology
    		256(5)
    20.4 Future Advancements in Ophthalmic Screening
    		261(1)
    20.5 Conclusions
    		262(4)
    21 Community Intervention Trials in Eye Health
    		266(9)
    Ving Fat Chan
    Prabhath Piyasena
    Priya Adhisesha Reddy
    Olusola Olawoye
    Nathan Congdon
    21.1 Introduction
    		266(1)
    21.2 Randomized Controlled Trials
    		266(1)
    21.3 Community Intervention Trials
    		266(5)
    21.4 Conclusions
    		271(4)
    Index 275
    Ching-Yu Cheng, MD, MPH, PhD - Professor, Duke-NUS Medical School, Singapore, Principal Clinician Scientist, Singapore Eye Research Institute. Senior Clinician Scientist, Singapore National Eye Centre

    Tien Y Wong, MD, PhD - Arthur Lim Professor of Ophthalmology, Medical Director, Singapore National Eye Centre, Chairman, Singapore Eye Research Institute, Vice Dean, Duke-NUS Medical School, Singapore
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