This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 8 parts: Honorary Lectures, Measuring Tissue Oxygen in vivo, Membrane-Level Transport, Hypoxia and Metabolic Regulation, Hemodynamic Physiology, Brain Functional Dynamics, Cerebral Hemodynamics, and Peripheral Oxygen Monitoring. The articles in this book have been presented at the 52nd annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2024). Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.
Role of mitochondrial optical redox imaging in modern cancer research.-
Mind the individual physiological reactions to long term colored light
exposure assessed by SPA.- A novel approach to in vivo EPR spectroscopy for
repeatable assessments of oxygenation levels in tumors at any depth
preliminary feasibility studies utilizing a multisite oxygen sensor inside
HDR brachytherapy needles.- What is the information content of EPR oximetry.-
Letting biology validate the EPR imaging of tumor.- Random acquisition of
spectral projections in four dimensional spectral spatial EPR imaging a
feasibility study toward oxygen imaging.- A portable broadband near infrared
spectroscopy device for in vivo oxygenation and metabolism measurements.- Non
contact oxygenation assessment of biological tissues based on a time of
flight method.- Dependence of reflectance on optical properties at short
distance.- Dependence of reflectance on optical properties at short
distance.- Influence of breast tumor associated lipids on oxygen transport
across model cell membranes.- Simulating gas permeation through the central
pore of AQP5.- Role of the dual specificity phosphatase signaling by hypoxia
or acidosis in tumor cells.- Blood flow regulates metabolism in hematopoietic
development.- Erythrocytes as active regulators of blood flow a brief
overview.- Capillary red blood cell velocity is decreased in skeletal muscle
of septic rats in vivo imaging using videocapillaroscopy.- The role of nitric
oxide in regulating microvascular oxygen pressure during diaphragm
contraction in rats.- Influence of arterial occlusion at various cuff
positions on systemic circulation measured by remote photoplethymography.-
Physiological effects of photobiomodulation therapy in the treatment of
multiple concussions.- Photobiomodulation increases eye movement conjugation
in healthy volunteers.- Brain synchronization when sharing positive emotions
based on memories hyperscanning study.- Unlocking unique physiological
reactions novel insights into four cerebral and systemic physiological
responses to colored light.- Long term modulation of brain tissue oxygenation
and electrophysiological activity following neonatal anesthesia exposure.-
Unravelling the connection between reduced mobility and mild cognitive
impairment in chronic pain patients through cluster analysis.- Time dependent
efficacy of drag reducing polymers in the treatment of permanent middle
cerebral artery occlusion injury in rats.- Prefrontal cortex oxygenation
dynamics during walking in patients with acute stroke.- Cerebral edema
depends on the results of large vascular occlusion reperfusion therapy.- Net
water uptake and cerebral microcirculation in perilesional penumbra in TBI CT
perfusion study.- Uncontrolled orthostatic hypotension and multi channel
cerebral hemodynamic changes in a young male participant a case report.-
Dynamic changes in cerebral oxygenation and arterial pressure during repeated
rapid hypotension.- Patients admitted to the ICU who cannot be mobilized for
the first time within hours have low regional cerebral oxygen
saturation.- derived muscle deoxygenation during arterial occlusion at rest
before and after body weight resistance training with slow movement and tonic
force generation.- Characteristics of muscle oxygenation of the upper and
lower limb during moderate intensity upper limb crank exercise a near
infrared spectroscopy study.- Compensatory oxygenation changes in non active
and active muscles during incremental exercise in healthy adults.- Pulse
oximeters accuracy and artifacts.
Sally C. Pias, PhD, is an Associate Professor in the Department of Chemistry at the New Mexico Institute of Mining and Technology (New Mexico Tech) in Socorro, New Mexico, USA. She specializes in the biophysics of molecular transport processes important in energy metabolism, tumor cell survival, and cell death.
Qi Wang, PhD, is an Assistant Professor of Biochemistry in the Department of Chemistry and Biochemistry at Presbyterian College in Clinton, South Carolina, USA. Her research uses molecular dynamics simulations to explore how biomolecular systems interact and change, with focus on membranes and proteins.
Joseph C. LaManna, PhD, is Jeannette M. and Joseph S. Silber Professor for the Study of Brain Sciences, affiliated with the Departments of Physiology and Biophysics; Neurology; and Neuroscience at Case Western Reserve University Medical School, Cleveland, Ohio, USA. His research focuses on physiological adaptations to mild hypoxia and on brain metabolism of ketones as an alternate fuel to glucose.
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