Preface |
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xvii | |
Contributors |
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xxi | |
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1 | (20) |
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1 A brief history of the Committee of Presidents of Statistical Societies (COPSS) |
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3 | (18) |
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3 | (3) |
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1.2 COPSS activities in the early years |
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6 | (2) |
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1.3 COPSS activities in recent times |
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8 | (2) |
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10 | (11) |
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II Reminiscences and personal reflections on career paths |
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21 | (118) |
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2 Reminiscences of the Columbia University Department of Mathematical Statistics in the late 1940s |
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23 | (6) |
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2.1 Introduction: Pre-Columbia |
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23 | (1) |
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24 | (2) |
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26 | (3) |
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29 | (12) |
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29 | (3) |
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3.2 Postdoc at University of Chicago |
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32 | (2) |
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3.3 University of Illinois and Stanford |
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34 | (4) |
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38 | (3) |
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4 "... how wonderful the field of statistics is ..." |
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41 | (8) |
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41 | (1) |
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4.2 The speech (edited some) |
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42 | (3) |
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45 | (4) |
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5 An unorthodox journey to statistics: Equity issues, remarks on multiplicity |
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49 | (10) |
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5.1 Pre-statistical career choices |
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49 | (1) |
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5.2 Becoming a statistician |
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50 | (2) |
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5.3 Introduction to and work in multiplicity |
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52 | (2) |
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5.4 General comments on multiplicity |
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54 | (5) |
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6 Statistics before and after my COPSS Prize |
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59 | (14) |
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59 | (1) |
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6.2 The foundation of mathematical statistics |
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59 | (1) |
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60 | (2) |
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62 | (5) |
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67 | (6) |
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7 The accidental biostatistics professor |
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73 | (10) |
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7.1 Public school and passion for mathematics |
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73 | (1) |
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7.2 College years and discovery of statistics |
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74 | (2) |
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7.3 Thwarted employment search after college |
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76 | (1) |
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7.4 Graduate school as a fallback option |
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76 | (1) |
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7.5 Master's degree in statistics at Purdue |
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77 | (1) |
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7.6 Thwarted employment search after Master's degree |
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77 | (1) |
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7.7 Graduate school again as a fallback option |
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77 | (1) |
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7.8 Dissertation research and family issues |
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78 | (1) |
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7.9 Job offers --- finally! |
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79 | (1) |
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7.10 Four years at UNC-Chapel Hill |
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79 | (1) |
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7.11 Thirty-three years at Emory University |
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80 | (1) |
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7.12 Summing up and acknowledgements |
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81 | (2) |
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8 Developing a passion for statistics |
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83 | (14) |
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83 | (2) |
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8.2 The first statistical seeds |
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85 | (1) |
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85 | (3) |
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88 | (4) |
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8.5 Job and postdoc hunting |
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92 | (1) |
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92 | (1) |
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8.7 Starting on the tenure track |
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93 | (4) |
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9 Reflections on a statistical career and their implications |
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97 | (12) |
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97 | (3) |
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9.2 Statistical diagnostics |
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100 | (4) |
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9.3 Optimal experimental design |
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104 | (1) |
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9.4 Enjoying statistical practice |
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105 | (1) |
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106 | (3) |
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10 Science mixes it up with statistics |
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109 | (8) |
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109 | (1) |
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110 | (1) |
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10.3 Some collaborative projects |
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111 | (3) |
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114 | (3) |
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11 Lessons from a twisted career path |
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117 | (12) |
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117 | (1) |
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118 | (4) |
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11.3 Becoming a researcher |
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122 | (5) |
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127 | (2) |
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129 | (10) |
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129 | (1) |
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12.2 The Elizabeth Scott Award |
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130 | (2) |
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132 | (2) |
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134 | (1) |
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134 | (2) |
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12.6 Underrepresented groups |
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136 | (3) |
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III Perspectives on the field and profession |
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139 | (96) |
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13 Statistics in service to the nation |
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141 | (12) |
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141 | (2) |
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13.2 The National Halothane Study |
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143 | (1) |
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13.3 The President's Commission and CNSTAT |
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144 | (1) |
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13.4 Census-taking and multiple-systems estimation |
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145 | (1) |
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13.5 Cognitive aspects of survey methodology |
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146 | (1) |
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13.6 Privacy and confidentiality |
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147 | (1) |
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13.7 The accuracy of the polygraph |
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148 | (1) |
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149 | (4) |
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153 | (4) |
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153 | (1) |
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153 | (1) |
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154 | (3) |
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15 We live in exciting times |
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157 | (14) |
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157 | (2) |
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159 | (2) |
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15.3 Living the revolution |
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161 | (10) |
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16 The bright future of applied statistics |
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171 | (6) |
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171 | (1) |
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16.2 Becoming an applied statistician |
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171 | (1) |
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16.3 Genomics and the measurement revolution |
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172 | (3) |
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175 | (2) |
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17 The road travelled: From statistician to statistical scientist |
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177 | (12) |
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177 | (1) |
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17.2 Kin-cohort study: My gateway to genetics |
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178 | (1) |
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17.3 Gene-environment interaction: Bridging genetics and theory of case-control studies |
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179 | (2) |
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17.4 Genome-wide association studies (GWAS): Introduction to big science |
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181 | (2) |
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17.5 The post-GWAS era: What does it all mean? |
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183 | (1) |
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184 | (5) |
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18 A journey into statistical genetics and genomics |
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189 | (14) |
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189 | (2) |
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18.2 My move into statistical genetics and genomics |
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191 | (1) |
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18.3 A few lessons learned |
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192 | (1) |
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18.4 A few emerging areas in statistical genetics and genomics |
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193 | (4) |
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18.5 Training the next generation statistical genetic and genomic scientists in the 'omics era |
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197 | (2) |
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199 | (4) |
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19 Reflections on women in statistics in Canada |
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203 | (14) |
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19.1 A glimpse of the hidden past |
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203 | (1) |
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19.2 Early historical context |
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204 | (2) |
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19.3 A collection of firsts for women |
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206 | (3) |
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209 | (1) |
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210 | (2) |
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19.6 Statistical practice |
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212 | (1) |
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213 | (4) |
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20 "The whole women thing" |
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217 | (12) |
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217 | (1) |
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20.2 "How many women are there in your department?" |
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218 | (2) |
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20.3 "Should I ask for more money?" |
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220 | (1) |
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221 | (3) |
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20.5 "I loved that photo" |
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224 | (1) |
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225 | (4) |
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21 Reflections on diversity |
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229 | (6) |
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229 | (1) |
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21.2 Initiatives for minority students |
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230 | (1) |
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21.3 Impact of the diversity programs |
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231 | (2) |
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233 | (2) |
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IV Reflections on the discipline |
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235 | (328) |
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22 Why does statistics have two theories? |
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237 | (16) |
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237 | (2) |
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22.2 65 years and what's new |
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239 | (1) |
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22.3 Where do the probabilities come from? |
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240 | (3) |
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22.4 Inference for regular models: Frequency |
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243 | (2) |
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22.5 Inference for regular models: Bootstrap |
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245 | (1) |
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22.6 Inference for regular models: Bayes |
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246 | (1) |
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22.7 The frequency-Bayes contradiction |
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247 | (1) |
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248 | (5) |
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23 Conditioning is the issue |
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253 | (14) |
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253 | (1) |
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23.2 Cox example and a pedagogical example |
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254 | (1) |
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23.3 Likelihood and stopping rule principles |
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255 | (2) |
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23.4 What it means to be a frequentist |
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257 | (2) |
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23.5 Conditional frequentist inference |
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259 | (5) |
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264 | (3) |
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24 Statistical inference from a Dempster--Shafer perspective |
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267 | (14) |
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267 | (1) |
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24.2 Personal probability |
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268 | (1) |
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24.3 Personal probabilities of "don't know" |
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269 | (2) |
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24.4 The standard DS protocol |
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271 | (4) |
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24.5 Nonparametric inference |
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275 | (1) |
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24.6 Open areas for research |
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276 | (5) |
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281 | (12) |
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281 | (3) |
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25.2 A brief history of NP Bayes |
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284 | (3) |
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25.3 Gazing into the future |
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287 | (6) |
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26 How do we choose our default methods? |
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293 | (10) |
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26.1 Statistics: The science of defaults |
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293 | (2) |
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295 | (2) |
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26.3 The pluralist's dilemma |
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297 | (2) |
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299 | (4) |
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27 Serial correlation and Durbin--Watson bounds |
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303 | (6) |
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303 | (1) |
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27.2 Circular serial correlation |
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304 | (1) |
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305 | (1) |
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27.4 Uniformly most powerful tests |
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305 | (1) |
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306 | (3) |
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28 A non-asymptotic walk in probability and statistics |
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309 | (14) |
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309 | (1) |
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310 | (5) |
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28.3 Welcome to Talagrand's wonderland |
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315 | (3) |
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28.4 Beyond Talagrand's inequality |
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318 | (5) |
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29 The past's future is now: What will the present's future bring? |
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323 | (12) |
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323 | (1) |
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324 | (1) |
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325 | (6) |
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331 | (4) |
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30 Lessons in biostatistics |
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335 | (14) |
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335 | (1) |
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30.2 It's the science that counts |
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336 | (2) |
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338 | (3) |
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341 | (4) |
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345 | (4) |
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31 A vignette of discovery |
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349 | (10) |
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349 | (1) |
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31.2 CMV infection and clinical pneumonia |
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350 | (4) |
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354 | (3) |
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357 | (2) |
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32 Statistics and public health research |
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359 | (10) |
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359 | (2) |
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32.2 Public health research |
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361 | (1) |
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32.3 Biomarkers and nutritional epidemiology |
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362 | (1) |
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32.4 Preventive intervention development and testing |
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363 | (2) |
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32.5 Clinical trial data analysis methods |
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365 | (1) |
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32.6 Summary and conclusion |
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365 | (4) |
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33 Statistics in a new era for finance and health care |
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369 | (12) |
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369 | (1) |
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33.2 Comparative effectiveness research clinical studies |
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370 | (1) |
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33.3 Innovative clinical trial designs in translational medicine |
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371 | (2) |
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33.4 Credit portfolios and dynamic empirical Bayes in finance |
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373 | (2) |
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33.5 Statistics in the new era of finance |
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375 | (1) |
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376 | (5) |
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34 Meta-analyses: Heterogeneity can be a good thing |
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381 | (10) |
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381 | (1) |
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34.2 Early years of random effects for meta-analysis |
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382 | (1) |
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34.3 Random effects and clinical trials |
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383 | (2) |
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34.4 Meta-analysis in genetic epidemiology |
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385 | (2) |
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387 | (4) |
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35 Good health: Statistical challenges in personalizing disease prevention |
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391 | (14) |
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391 | (1) |
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35.2 How do we personalize disease risks? |
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391 | (2) |
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35.3 How do we evaluate a personal risk model? |
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393 | (1) |
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35.4 How do we estimate model performance measures? |
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394 | (3) |
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35.5 Can we improve how we use epidemiological data for risk model assessment? |
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397 | (4) |
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401 | (4) |
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405 | (8) |
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405 | (4) |
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409 | (4) |
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37 Survey sampling: Past controversies, current orthodoxy, and future paradigms |
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413 | (16) |
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413 | (2) |
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37.2 Probability or purposive sampling? |
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415 | (1) |
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37.3 Design-based or model-based inference? |
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416 | (7) |
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37.4 A unified framework: Calibrated Bayes |
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423 | (2) |
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425 | (4) |
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38 Environmental informatics: Uncertainty quantification in the environmental sciences |
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429 | (22) |
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429 | (1) |
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38.2 Hierarchical statistical modeling |
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430 | (1) |
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38.3 Decision-making in the presence of uncertainty |
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431 | (2) |
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433 | (1) |
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38.5 EI for spatio-temporal data |
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434 | (10) |
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38.6 The knowledge pyramid |
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444 | (1) |
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444 | (7) |
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39 A journey with statistical genetics |
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451 | (14) |
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451 | (1) |
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39.2 The 1970s: Likelihood inference and the EM algorithm |
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452 | (2) |
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39.3 The 1980s: Genetic maps and hidden Markov models |
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454 | (1) |
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39.4 The 1990s: MCMC and complex stochastic systems |
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455 | (2) |
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39.5 The 2000s: Association studies and gene expression |
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457 | (1) |
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39.6 The 2010s: From association to relatedness |
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458 | (1) |
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458 | (7) |
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40 Targeted learning: From MLE to TMLE |
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465 | (16) |
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465 | (2) |
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40.2 The statistical estimation problem |
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467 | (2) |
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40.3 The curse of dimensionality for the MLE |
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469 | (4) |
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473 | (1) |
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474 | (2) |
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476 | (1) |
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477 | (4) |
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41 Statistical model building, machine learning, and the ah-ha moment |
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481 | (16) |
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41.1 Introduction: Manny Parzen and RKHS |
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481 | (9) |
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41.2 Regularization methods, RKHS and sparse models |
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490 | (1) |
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41.3 Remarks on the nature-nurture debate, personalized medicine and scientific literacy |
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491 | (1) |
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492 | (5) |
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42 In praise of sparsity and convexity |
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497 | (10) |
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497 | (1) |
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42.2 Sparsity, convexity and l1 penalties |
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498 | (2) |
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500 | (1) |
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500 | (3) |
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503 | (4) |
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43 Features of Big Data and sparsest solution in high confidence set |
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507 | (18) |
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507 | (1) |
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508 | (1) |
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509 | (1) |
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43.4 Spurious correlation |
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510 | (2) |
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43.5 Incidental endogeneity |
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512 | (3) |
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515 | (1) |
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43.7 Sparsest solution in high confidence set |
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516 | (5) |
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521 | (4) |
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525 | (12) |
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525 | (1) |
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44.2 The conference culture |
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526 | (1) |
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44.3 Neglected research areas |
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527 | (1) |
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527 | (6) |
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44.5 Computational thinking |
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533 | (1) |
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44.6 The evolving meaning of data |
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534 | (1) |
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44.7 Education and hiring |
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535 | (1) |
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44.8 If you can't beat them, join them |
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535 | (2) |
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45 A trio of inference problems that could win you a Nobel Prize in statistics (if you help fund it) |
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537 | (26) |
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45.1 Nobel Prize? Why not COPSS? |
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537 | (2) |
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45.2 Multi-resolution inference |
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539 | (6) |
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45.3 Multi-phase inference |
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545 | (6) |
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45.4 Multi-source inference |
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551 | (6) |
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45.5 The ultimate prize or price |
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557 | (6) |
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V Advice for the next generation |
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563 | |
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46 Inspiration, aspiration, ambition |
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565 | (6) |
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46.1 Searching the source of motivation |
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565 | (1) |
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46.2 Examples of inspiration, aspiration, and ambition |
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566 | (1) |
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46.3 Looking to the future |
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567 | (4) |
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47 Personal reflections on the COPSS Presidents' Award |
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571 | (10) |
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47.1 The facts of the award |
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571 | (1) |
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571 | (1) |
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47.3 Luck: Have a wonderful Associate Editor |
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572 | (1) |
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47.4 Find brilliant colleagues |
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572 | (2) |
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47.5 Serendipity with data |
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574 | (1) |
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47.6 Get fascinated: Heteroscedasticity |
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575 | (1) |
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47.7 Find smart subject-matter collaborators |
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575 | (2) |
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47.8 After the Presidents' Award |
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577 | (4) |
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48 Publishing without perishing and other career advice |
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581 | (12) |
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581 | (1) |
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48.2 Achieving balance, and how you never know |
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582 | (4) |
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48.3 Write it, and write it again |
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586 | (4) |
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590 | (3) |
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49 Converting rejections into positive stimuli |
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593 | (12) |
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594 | (1) |
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594 | (1) |
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49.3 My first JASA submission |
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595 | (1) |
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596 | (1) |
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49.5 Find reviewers who understand |
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597 | (1) |
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49.6 Sometimes it's easy, even with errors |
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598 | (1) |
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49.7 It sometimes pays to withdraw the paper! |
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598 | (3) |
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601 | (4) |
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50 The importance of mentors |
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605 | (10) |
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605 | (1) |
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50.2 The years at Princeton University |
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606 | (2) |
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50.3 Harvard University --- the early years |
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608 | (1) |
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50.4 My years in statistics as a PhD student |
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609 | (1) |
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610 | (1) |
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50.6 Interim time in DC at EPA, at the University of Wisconsin, and the University of Chicago |
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611 | (1) |
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50.7 The three decades at Harvard |
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612 | (1) |
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612 | (3) |
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51 Never ask for or give advice, make mistakes, accept mediocrity, enthuse |
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615 | (6) |
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51.1 Never ask for or give advice |
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615 | (1) |
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616 | (1) |
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617 | (1) |
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618 | (3) |
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621 | |
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621 | (1) |
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52.2 Thirteen rules for giving a really bad talk |
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621 | |