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1 Introduction and Motivation for Conducting Medical Image Analysis |
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1 | (26) |
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1.1 Introduction to Time-Resolved Terahertz Spectroscopy and Imaging |
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2 | (8) |
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1.1.1 Time Domain and Frequency Domain THz Spectroscopy |
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2 | (6) |
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1.1.2 Recent Advances in Simultaneous Time-Frequency Dependent THz Spectroscopy |
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8 | (2) |
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1.2 The Application of Magnetic Resonance to Biomedical Imaging |
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10 | (7) |
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1.3 Placing THz Imaging and MRI Time-Series in a Common Signal Processing Framework |
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17 | (2) |
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1.4 Introduction to Retinal Fundus Imaging |
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19 | (3) |
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1.5 Introduction to Optical Coherence Tomography (OCT) |
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22 | (5) |
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2 Overview of Clinical Applications Using THz Pulse Imaging, MRI, OCT and Fundus Imaging |
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27 | (24) |
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2.1 Recent Advances in the Application of THz Pulse Spectroscopy to Biomedical Imaging |
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27 | (24) |
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2.1.1 THz Radiation Absorption and Detection in Tissue |
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28 | (1) |
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2.1.2 Identification of Compounds with Complex Composition |
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29 | (2) |
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2.1.3 Recent Advances in the Application of DCE-MRI Imaging Techniques to Biomedical Imaging |
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31 | (2) |
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2.1.4 Recent Advances in the Application of fMRI Imaging to Biomedical Imaging |
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33 | (3) |
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2.1.5 Advantages and Shortfalls of T-Rays and DCE-MRI & FMRI |
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36 | (2) |
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2.1.6 Combining MRI with Alternative THz Spectrometric Systems and Other Imaging Modalities |
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38 | (7) |
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2.1.7 Recent Advances in the Application of the Fundus Camera to Disease Diagnosis |
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45 | (2) |
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2.1.8 Recent Advances in the Application of OCT Techniques to Disease Diagnosis |
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47 | (2) |
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2.1.9 Alternative Multichannel and MEMS Based OCT Imaging Modalities |
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49 | (2) |
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3 Recent Advances in Medical Data Preprocessing and Feature Extraction Techniques |
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51 | (42) |
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3.1 Overview of Medical Image Data Preprocessing Strategies |
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52 | (12) |
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3.1.1 Data Windowing and Model Fitting Parametric Approaches |
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52 | (1) |
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3.1.2 Multi-resolution Wavelet Analysis for Noise Removal |
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53 | (4) |
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3.1.3 Current Standards and Recent Developments in Multiresolution Feature Representation in Imaging |
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57 | (2) |
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3.1.4 Recent Advances in MRI Wavelet Denoising |
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59 | (1) |
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3.1.5 Recent Advances in Fundus Image Denoising |
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60 | (3) |
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3.1.6 The Need for a Multiresolution Image Fusion Approach |
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63 | (1) |
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3.2 Overview of Feature Selection Strategies |
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64 | (29) |
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3.2.1 Feature Selection Strategies in THz TPI Datasets |
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64 | (7) |
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3.2.2 Feature Extraction and Selection on the Basis of Cross-correlation Sequences |
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71 | (3) |
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3.2.3 Feature Selection Strategies for MRI Datasets |
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74 | (5) |
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3.2.4 Spatiotemporal Correlations and Cluster Analysis of Brain Activity Using fMRI |
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79 | (6) |
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3.2.5 Feature Selection in Retinal Fundus Photography Following Image Enhancement |
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85 | (5) |
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3.2.6 Feature Extraction and Pattern Identification of Pathology Distortion in SD-OCT Imaging |
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90 | (2) |
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3.2.7 Statistical Analysis Based on Feature Selection Strategies |
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92 | (1) |
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93 | (36) |
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4.1 Introduction to Pattern Classification |
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93 | (1) |
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4.2 Feature Based Mahalanobis Distance Classifiers |
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94 | (1) |
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4.3 Support Vector Machine Classifiers (SVMs) |
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95 | (6) |
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4.3.1 Binary Classification of SVMs |
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95 | (3) |
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4.3.2 Pairwise SVM Classification of Multiple Classes |
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98 | (1) |
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4.3.3 Application of SVM Classifiers to THz-TPI Measurements |
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99 | (2) |
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4.4 Real-Valued Extreme Learning Machine Classifier |
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101 | (2) |
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4.5 Complex Valued ELMs for Classification |
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103 | (20) |
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4.5.1 Review of Complex-Valued RKHS and Wirtinger's Calculus |
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103 | (2) |
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4.5.2 Defining Higher-Dimension Hyprplanes Using Quaternion and Other Division Algebras for Classification |
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105 | (5) |
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4.5.3 Determination of the Maximum-Margin Hyperplanes ofCELM |
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110 | (7) |
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4.5.4 Multinomial Logistic Regression Classifier with Ridge Estimators (MLR) |
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117 | (1) |
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4.5.5 Naive Bayesian (NB) Classifier |
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118 | (1) |
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4.5.6 Performance Evaluation of Several Different Classifiers |
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118 | (3) |
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4.5.7 Clustering Techniques to Segment THz Images |
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121 | (2) |
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4.6 Retinal Fundus Image Analysis via Supervised and Non-supervised Learning |
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123 | (6) |
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4.6.1 Fundus Image Vessel Segmentation |
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123 | (1) |
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4.6.2 Algorithmic Detection of the Optic Disk |
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124 | (2) |
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4.6.3 Retinal Vessel Classification: Identifying and Sorting Arteries and Veins |
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126 | (1) |
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4.6.4 Automated Image Classification Using Criteria Directly Developed from Clinicians |
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127 | (2) |
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5 Introduction to MRI Time Series Image Analysis Techniques |
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129 | (36) |
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5.1 Analysis of DCE-MRI Data |
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129 | (5) |
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5.1.1 Outlook for Future Tensorial Algebra Based Feature and Image Registration |
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131 | (2) |
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5.1.2 Performance Measures |
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133 | (1) |
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5.2 Tensorial Representations in MRI |
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134 | (2) |
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5.3 Extensions to Multi-channel Classifiers |
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136 | (7) |
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5.3.1 Suppression of Background Voxels Through Multi-channel Reconstruction |
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140 | (1) |
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5.3.2 Increased Image Contrast Between Tumours and Background Through Multi-channel Reconstruction |
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141 | (2) |
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5.4 Image Registration of MRIs |
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143 | (3) |
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5.5 Pattern Identification of Spatiotemporal Association of Features in Tumours from DCE-MRI Data |
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146 | (3) |
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5.6 Pattern Classification of Spatiotemporal Association Features in fMRI Data |
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149 | (16) |
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5.6.1 Supervised Tensor Learning of Brain Disorders in fMRI Datasets |
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149 | (2) |
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5.6.2 Supervised Multivariate Learning of Brain Disorders from fMRI Data |
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151 | (3) |
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5.6.3 Topological Graph Kernel on Multiply Thresholded Functional Connectivity Networks |
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154 | (6) |
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5.6.4 Machine Learning Using Information from Brain Graphs |
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160 | (1) |
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5.6.5 Additional Considerations Regarding MRI Feature Extraction Methodologies |
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161 | (2) |
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5.6.6 Recent Relevant Advances from the Computer Vision Community |
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163 | (2) |
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6 Outlook for Clifford Algebra Based Feature and Deep Learning AI Architectures |
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165 | (14) |
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6.1 Prospects for Medical Image Analysis Under a Clifford Algebra Framework |
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165 | (4) |
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6.2 Outlook for Developing a Geometric Neuron Deep Learning of Time Series Datasets in Medical Images |
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169 | (8) |
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6.3 Prospects for Alternative Classifiers in Deep Learning of Unlabelled Medical Image Data |
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177 | (2) |
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179 | (4) |
References |
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183 | (32) |
Index |
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215 | |