With complete, concise coverage of prevention, indications, diagnosis, and treatment, Pediatric Allergy, 4th Edition, is your go-to resource for current, clinically-focused content in the rapidly changing field of allergies and immune-mediated diseases in children. This highly regarded reference fully covers immunology and origins of allergy, growth and development, pregnancy, infancy, and early, middle, and late childhood-all with a new, practical, clinical focus. You'll find authoritative coverage of the full range of allergies in pediatric patients, from asthma and other common conditions to rare or uncommon allergies, providing a one-stop resource for clinicians across specialties who care for children.
- Focuses on the clinical application of science to the bedside, including clinical pearls discussing best practice approaches and guidelines.?
- Integrates the latest research on the origins of allergy in early life, including pregnancy, the neonate, and infants.
- Includes new, evidence-based management guidelines for various diseases, including food allergy, atopic dermatitis, asthma and immunodeficiency.
- Provides new content on the prevention of allergies; asthma, eczema, and food allergies in young children; and extensive current guidelines and new therapies.
- Offers up-to-date information on key areas such as food challenges, skin testing, IgE diagnostic labs, immunotherapy, clinical immunology diagnostic testing, molecular diagnostics, and lung function testing.
- Highlights current guidance from a new team of leading experts with 150 anatomic schematics, clinical photos, and algorithms-many new to this edition.
- Covers gene therapy, stem-cell therapy, and a host of immunodeficiency diseases found in children with allergies.
- Discusses targeted biologics for severe allergic diseases, defects of innate immunity, rheumatic diseases of childhood, and inflammatory disorders.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Arvustused
"All in all this book covers vast range of topics related with indoor, out-door allergen induced responses including the basic principles of immunology and diseases in children. Primarily, this multi-author book presents deeper understanding of the pathophysiology in a concerted manner. The same makes this book collectable for those clinicians interested in most up-to-date text on allergic conditions and the generalists who will benefitting from learning about wide range of expressions of Immunological challenges children are exposed to in the modern age."
| Contributors |
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vii | |
| Preface |
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xii | |
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Section A General Concepts |
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1 Epidemiology of Allergic Diseases |
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1 | (6) |
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2 Natural History of Allergic Diseases and Asthma |
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7 | (9) |
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3 The Genetics of Allergic Disease and Asthma |
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16 | (14) |
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Section B Immunologic Diseases |
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4 Approach to the Child With Recurrent Infections and Molecular Diagnosis |
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30 | (8) |
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Charlotte Cunningham-Rundles |
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5 Primary Antibody Deficiency |
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38 | (6) |
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6 T Cell Immunodeficiencies |
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44 | (11) |
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7 Complement Deficiencies |
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55 | (9) |
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8 Defects of Innate Immunity |
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64 | (11) |
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9 Congenital Immune Dysregulation Disorders |
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75 | (9) |
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10 Immunoglobulin Therapy |
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84 | (8) |
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11 Hematopoietic Stem Cell Therapies |
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92 | (7) |
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Section C Diagnosis and Treatment of Allergic Disease |
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12 Diagnosis of Human Allergic Disease |
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99 | (10) |
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109 | (6) |
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115 | (5) |
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120 | (6) |
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16 Immunotherapy for Allergic Disease |
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126 | (9) |
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Section D Upper Airway Disease |
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135 | (12) |
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147 | (11) |
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158 | (9) |
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20 Immunology of the Asthmatic Response |
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167 | (11) |
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21 Lung Function Testing in Children |
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178 | (7) |
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22 Infections and Asthma in Childhood |
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185 | (8) |
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23 Special Considerations for Infants and `Young Children' |
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193 | (16) |
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24 Inner City Asthma: Strategies to Reduce Mortality and Morbidity |
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209 | (7) |
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25 Asthma in Older Children: Special Considerations |
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216 | (12) |
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26 Collaborating With Schools to Support Children With Asthma |
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228 | (8) |
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27 Refractory Childhood Asthma: Assessment and Management |
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236 | (11) |
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28 Promoting Adherence and Self-Management |
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247 | (4) |
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29 Strategies for the Primary Prevention of Asthma |
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251 | (6) |
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30 Mucosal Immunology: An Overview |
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257 | (7) |
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31 Evaluation of Food Allergy |
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264 | (6) |
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32 Approach to Feeding Problems in the Infant and Young Child |
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270 | (5) |
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33 Enterocolitis, Proctocolitis, and Enteropathies |
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275 | (9) |
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34 Eosinophilic Gastrointestinal Diseases |
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284 | (7) |
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35 Management of Food Allergy |
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291 | (10) |
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36 Prevention of Food Allergy |
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301 | (6) |
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37 Immunotherapeutic Approaches to the Treatment of Food Allergy |
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307 | (11) |
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Section G Allergic Skin Diseases |
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38 Evaluation and Management of Atopic Dermatitis |
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318 | (11) |
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39 Urticaria and Angioedema |
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329 | (11) |
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340 | (14) |
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Section H Other Allergic Diseases |
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41 Allergic and Immunologic Eye Disease |
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354 | (14) |
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368 | (7) |
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375 | (12) |
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Hanneke (Joanne) N.G. Oude Elberink |
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44 Anaphylaxis: Assessment and Management |
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387 | (13) |
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45 Mast Cell Disease and Hypereosinophilic Diseases |
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400 | (10) |
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| Index |
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410 | |
Scott H. Sicherer, M.D., is the Elliot and Roslyn Jaffe professor of allergy, immunology and pediatrics at the Icahn School of Medicine at Mount Sinai and the Director of the Jaffe Food Allergy Institute. He is Chief of the Division of Pediatric Allergy and Immunology, and Medical Director of the Institution's Clinical Research Unit. Sicherer received his medical degree from the Johns Hopkins University School of Medicine. He is board-certified in allergy and immunology and specializes in food allergies. His research interests include gastrointestinal manifestations, epidemiology, psychosocial and quality of life issues, diagnostics, prevention, genetics and treatments.
He has published over 275 articles and 75 book chapters in major pediatric and allergy textbooks and journals, and has been consistently recognized as among the top 1% of researchers in his field. Hugh A Sampson, MD, is the Kurt Hirschhorn Professor of Pediatrics, the Dean for Translational Biomedical Sciences, PI and Director of Conduits; Institutes for Translational Sciences (CTSA), and the Director of the Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Sampson completed his allergy/immunology fellowship training at Duke University in 1980 and was a faculty member in the Division of Allergy/Immunology at Duke University and then Johns Hopkins University before coming to Mount Sinai. Dr. Sampson's research interests have focused primarily on food allergic disorders including the immunopathogenic role of food hypersensitivity in atopic dermatitis and anaphylaxis, characterization of food allergens, and improved diagnostic tests and immunotherapeutic strategies for treating food allergies. Dr. Sampson is the PI of the NIH-sponsored Consortium on Food Allergy Research and an AADCRC program project conducting a number of clinical trials investigating novel therapies for the treatment of food allergy and investigating basic immunologic mechanisms associated with desensitization and the eventual development of tolerance. He has published over 400 articles and 60 book chapters on food allergic disorders and co-edited four books, and was elected to membership in the Institute of Medicine of the National Academies in 2003 for his research in food allergies. Dr. Sampson is past chairman of the Section on Allergy & Immunology of the American Academy of Pediatrics and the past-president of the American Academy of Allergy, Asthma and Immunology.
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