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E-raamat: Poisoning and Drug Overdose, Eighth Edition

  • Formaat: 784 pages
  • Ilmumisaeg: 22-Apr-2022
  • Kirjastus: McGraw-Hill Education
  • Keel: eng
  • ISBN-13: 9781264259090
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  • Formaat: 784 pages
  • Ilmumisaeg: 22-Apr-2022
  • Kirjastus: McGraw-Hill Education
  • Keel: eng
  • ISBN-13: 9781264259090
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When every moment counts, count on Poisoning & Drug Overdose

A Doody's Core Title for 2024 & 2023! 

Speed is crucial when dealing with toxicologic and drug-related emergencies. Finding answers quickly is easier than ever with this streamlined eighth edition of Poisoning and Drug Overdose. This instant-answer guide provides the critical information needed to diagnose and manage drug-related emergencies and chemical exposures.

Updated with newly released drugs and new information on existing drugs, the guide covers initial emergency management, including treatment of coma, seizures and hypotension; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons.

Poisoning and Drug Overdose, Eighth Edition is divided into four sections:









Section I. Provides a stepwise approach to the evaluation and treatment of coma, seizures, shock, and other complications of poisoning and the proper use of gastric decontamination and dialysis procedures.

Section II. Lists specific poisons and drugs, as well as the pathophysiology, toxic dose and level, clinical presentation, diagnosis, and specific treatment associated with each substance.

Section III. Covers descriptions of therapeutic drugs and antidotes, including pharmacology indications, adverse effects, drug interactions, and recommended dosage.

Section IV. Describes the approach to hazardous materials incidents; the evaluation of occupational exposures; and the toxic effects, physical properties, and workplace limits for over 500 common industrial chemicals.







Poisoning and Drug Overdose, Eighth Edition is enhanced by numerous tables and charts, as well as a user-friendly index. This trusted resource has consistently been relied upon by front line professionals responding to drug-related emergencies and chemical exposures.
Authors xi
Preface and Acknowledgements xvii
Section I Comprehensive Evaluation and Treatment
73(406)
Airway
1(3)
Breathing
4(4)
Ventilatory Failure
4(1)
Hypoxia
5(2)
Bronchospasm
7(1)
Circulation
8(11)
Bradycardia and Atrioventricular Block
8(1)
QRS Interval Prolongation
9(3)
Tachycardia
12(1)
Ventricular Dysrhythmias
13(2)
Hypotension
15(2)
Hypertension
17(2)
Altered Mental Status
19(7)
Coma and Stupor
19(1)
Hypothermia
20(1)
Hyperthermia
21(2)
Seizures
23(2)
Agitation, Delirium, or Psychosis
25(1)
Other complications
26(4)
Dystonia, Dyskinesia, and Rigidity
26(2)
Rhabdomyolysis
28(1)
Anaphylactic and Anaphylactoid Reactions
29(1)
Diagnosis of Poisoning
30(21)
History
30(1)
Physical Examination
30(4)
Essential Clinical Laboratory Tests
34(1)
Serum Osmolality and Osmol gap
34(2)
Anion Gap Metabolic Acidosis
36(1)
Hyperglycemia and Hypoglycemia
37(1)
Hypernatremia and Hyponatremia
38(3)
Hyperkalemia and Hypokalemia
41(1)
Renal Failure
42(1)
Hepatic Failure
43(1)
Toxicology Screening
44(6)
Imaging Studies
50(1)
Decontamination
51(5)
Skin decontamination
51(1)
Decontamination of the Eyes
51(1)
Decontamination after Inhalation
52(1)
Gastrointestinal Decontamination
52(1)
Gastric Lavage
53(1)
Activated Charcoal
54(1)
Whole-bowel Irrigation
55(1)
Enhanced Elimination
56(4)
Urinary pH Manipulation
59(1)
Hemodialysis
59(1)
Hemoperfusion
59(1)
Peritoneal Dialysis
59(1)
Continuous Renal Replacement Therapy
59(1)
Repeat-dose Activated Charcoal
59(1)
Disposition of the Patient
60(2)
Special Considerations in Pediatric Patients
62(3)
Pregnancy and Breastfeeding
65(5)
Forensic Issues/Postmortem Toxicology
70(1)
Evaluation of Drug-Facilitated Crimes
71(408)
Section II Specific Poisons and Drugs: Diagnosis and Treatment
479(118)
Acetaminophen
74(4)
Aconite and Other Sodium Channel Openers
78(1)
Amantadine
79(1)
Ammonia
80(2)
Amphetamines
82(4)
Anesthetics, Local
86(2)
Angiotensin Blockers and ACE Inhibitors
88(2)
Antiarrhythmic Drugs
90(3)
Antibacterial Agents
93(5)
Anticholinergics
98(1)
Anticoagulants, Direct Oral
99(3)
Anticonvulsants, Newer
102(2)
Antidepressants, General (Noncyclic)
104(3)
Antidepressants, Tricyclic
107(3)
Antihistamines
110(3)
Antimony and Stibine
113(2)
Antineoplastic Agents
115(15)
Antipsychotic Drugs
130(2)
Antiseptics and Disinfectants
132(2)
Antiviral and Antiretroviral Agents
134(4)
Arsenic
138(4)
Arsine
142(3)
Asbestos
145(1)
Azide, Sodium
146(1)
Barbiturates
147(2)
Barium
149(2)
Benzene
151(2)
Benzodiazepines
153(2)
Beta-adrenergic Blockers
155(2)
Beta2-adrenergic Stimulants
157(2)
Boric acid, Borates, and Boron
159(1)
Botulism
160(3)
Bromates
163(1)
Bromides
164(1)
Cadmium
165(2)
Caffeine
167(2)
Calcium Channel Antagonists
169(3)
Camphor and Other Essential Oils
172(2)
Carbamazepine and Oxcarbazepine
174(3)
Carbon Disulfide
177(1)
Carbon Monoxide
178(3)
Carbon Tetrachloride and Chloroform
181(1)
Caustic and Corrosive Agents
182(3)
Chlorates
185(1)
Chlorinated Hydrocarbon Pesticides
186(1)
Chlorine
187(2)
Chlorophenoxy Herbicides (2,4-D)
189(1)
Chloroquine and Other Aminoquinolines
190(2)
Chromium
192(2)
Clonidine and Related Drugs
194(2)
Cobalt
196(2)
Cocaine
198(3)
Colchicine
201(2)
Copper
203(2)
Cyanide
205(2)
Dapsone
207(3)
Detergents
210(2)
Dextromethorphan
212(2)
Diabetic Drugs
214(4)
Digoxin and Other Cardiac Glycosides
218(3)
Dioxins
221(1)
Disulfiram
222(2)
Diuretics
224(2)
Ergot Derivatives
226(2)
Ethanol
228(3)
Ethylene Glycol and Other Glycols
231(4)
Ethylene Oxide
235(1)
Fluoride
236(2)
Fluoroacetate
238(2)
Food Poisoning: Bacterial
240(2)
Food Poisoning: Fish and Shellfish
242(4)
Formaldehyde
246(1)
Freons and Halons
247(2)
Gamma-hydroxybutyrate (GHB)
249(2)
Gases, Irritant
251(2)
Glyphosate
253(2)
Heparins
255(2)
Herbal and Alternative Products
257(6)
Hydrocarbons
263(3)
Hydrogen Fluoride and Hydrofluoric Acid
266(3)
Hydrogen Sulfide
269(1)
Hymenoptera
270(1)
Iodine
271(2)
Iron
273(2)
Isocyanates
275(1)
Isoniazid (INH)
276(2)
Isopropyl Alcohol
278(2)
Jellyfish and Other Cnidaria
280(2)
Lead
282(5)
Lionfish and Other Scorpaenidae
287(2)
Lithium
289(2)
Lomotil and Other Antidiarrheals
291(2)
Lysergic Acid Diethylamide (LSD) and Other Hallucinogens
293(4)
Magnesium
297(2)
Manganese
299(1)
Marijuana and Cannabinoids
300(3)
Mercury
303(5)
Metal Fume Fever
308(1)
Metaldehyde
309(1)
Metformin
310(2)
Methanol
312(2)
Methemoglobinemia
314(2)
Methotrexate
316(2)
Methyl Bromide
318(2)
Methylene Chloride
320(2)
Molds
322(2)
Monoamine Oxidase Inhibitors
324(3)
Mushrooms
327(3)
Mushroom, Amatoxin-Type
330(2)
Naphthalene and Paradichlorobenzene
332(2)
Nicotine
334(2)
Nitrates and Nitrites
336(2)
Nitrogen Oxides
338(1)
Nitroprusside
339(1)
Nitrous Oxide
340(2)
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
342(2)
Nontoxic or Minimally Toxic Household Products
344(2)
Opiates and Opioids
346(3)
Organophosphorus and Carbamate Insecticides
349(9)
Oxalic Acid
358(1)
Paraquat and Diquat
359(2)
Pentachlorophenol and Dinitrophenol
361(1)
Phencyclidine (PCP) and Ketamine
362(3)
Phenol and Related Compounds
365(1)
Phenytoin
366(2)
Phosgene
368(1)
Phosphine and Phosphides
369(2)
Phosphorus
371(1)
Plants
372(19)
Polychlorinated Biphenyls (PCBs)
391(2)
Pseudoephedrine, Phenylephrine, and Other Decongestants
393(2)
Pyrethrins and Pyrethroids
395(2)
Quinidine and Other Type la Antiarrhythmic Drugs
397(1)
Quinine
398(2)
Radiation (Ionizing)
400(4)
Rodenticides, Miscellaneous
404(5)
Salicylates
409(2)
Scorpions
411(2)
Sedative-Hypnotic Agents
413(2)
Selenium
415(2)
Skeletal Muscle Relaxants
417(2)
Smoke Inhalation
419(2)
Snakebite
421(4)
Spiders
425(3)
Strychnine
428(1)
Sulfur Dioxide
429(1)
Tetanus
430(2)
Thallium
432(1)
Theophylline
433(2)
Thyroid Hormone
435(1)
Toluene and Xylene
436(2)
Trichloroethane, Trichloroethylene, and Tetrachloroethylene
438(2)
Valproic Acid
440(3)
Vasodilators
443(1)
Vitamins
444(2)
Warfare Agents - Biological
446(5)
Warfare Agents - Chemical
451(7)
Warfarin and Superwarfarins
458(3)
Pharmacokinetic Data
461(136)
Section III Therapeutic Drugs and Antidotes
597(124)
Acetylcysteine (NAC)
481(3)
Andexanet Alpha
484(2)
Antipsychotic Drugs (Haloperidol, Droperidol, Olanzapine, and Ziprasidone)
486(2)
Antivenom, Centruroides (Scorpion)
488(1)
Antivenom, Crotalidae (Rattlesnake)
489(2)
Antivenom, Latrodectus Mactans (Black Widow Spider)
491(1)
Antivenom, Micrurus Fulvius (Coral Snake) and Exotic Antivenoms
492(2)
Atropine and Glycopyrrolate
494(1)
BAL (Dimercaprol)
495(2)
Benzodiazepines (Diazepam, Lorazepam, and Midazolam)
497(3)
Benztropine
500(1)
Bicarbonate, Sodium
501(2)
Botulism Antitoxin
503(1)
Bromocriptine
504(2)
Calcium
506(2)
Carnitine (Levocarnitine)
508(1)
Charcoal, Activated
509(2)
Cimetidine and Other H2 Blockers
511(1)
Clotting Factor Replacement Products
512(3)
Cyproheptadine
515(1)
Dantrolene
515(2)
Deferoxamine
517(1)
Dexmedetomidine
518(1)
Digoxin-Specific Antibodies
519(2)
Diphenhydramine
521(1)
Dopamine
522(2)
DTPA (Diethylenetriaminepentaacetate)
524(1)
EDTA, Calcium (Calcium Disodium Edetate, Calcium Disodium Versenate)
525(2)
Epinephrine
527(2)
Esmolol
529(1)
Ethanol
530(2)
Flumazenil
532(1)
Folic Acid
533(1)
Fomepizole (4-Methylpyrazole, 4-MP)
534(2)
Glucagon
536(1)
Glucarpidase
537(1)
Glucose (Dextrose)
538(1)
Hydroxocobalamin
539(1)
Idarucizumab
540(1)
Insulin
541(1)
Iodide (Potassium Iodide, Kl)
542(2)
Isoproterenol
544(1)
Ketamine
545(2)
Labetalol
547(1)
Leucovorin Calcium
548(1)
Lidocaine
549(1)
Lipid Emulsion
550(2)
Magnesium
552(1)
Mannitol
553(1)
Methylene Blue
554(1)
Metoclopramide
555(2)
Naloxone
557(2)
Neuromuscular Blockers
559(4)
Nitrite, Sodium and Amyl
563(1)
Nitroprusside
564(1)
Norepinephrine
565(2)
Octreotide
567(1)
Ondansetron
568(1)
Oxygen and Hyperbaric Oxygen
569(2)
Penicillamine
571(1)
Pentobarbital
572(1)
Phenobarbital
573(2)
Phentolamine
575(1)
Phenylephrine
575(1)
Physostigmine and Neostigmine
576(2)
Potassium
578(1)
Pralidoxime (2-PAM) and Other Oximes
579(2)
Propofol
581(2)
Propranolol
583(2)
Protamine
585(1)
Prussian Blue
586(1)
Pyridoxine (Vitamin B6)
587(1)
Silibinin
588(1)
Succimer (DMSA)
589(2)
Thiamine (Vitamin B1)
591(1)
Thiosulfate, Sodium
592(1)
Unithiol (DMPS)
593(2)
Vasopressin
595(1)
Vitamin K, (Phytonadione)
596(125)
Section IV Environmental and Occupational Toxicology
721(2)
Emergency Medical Response to Hazardous Materials Incidents
598(8)
Evaluation of the Patient with Occupational Chemical Exposure
606(9)
The Toxic Hazards of Industrial and Occupational Chemicals
615(6)
Health Hazard Summaries for Industrial and Occupational Chemicals
621(102)
Index 723
Kent R. Olson, MD, FACEP Medical Director California Poison ontrol System, San Francisco Division San Francisco General Hospital Attenting Emergency Physician Elden Hospital Medcial Center Clinical Professor of Medicine, Pediatrics, and Pharmacy University of California, San Francisco