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E-raamat: Precision Medicine Oncology: A Primer

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  • Formaat: PDF+DRM
  • Ilmumisaeg: 13-Sep-2019
  • Kirjastus: Rutgers University Press
  • Keel: eng
  • ISBN-13: 9780813575896
  • Formaat - PDF+DRM
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  • Formaat: PDF+DRM
  • Ilmumisaeg: 13-Sep-2019
  • Kirjastus: Rutgers University Press
  • Keel: eng
  • ISBN-13: 9780813575896

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Precision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, and intended for clinicians, particularly those working in the field of oncology.

Precision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. This is made possible, in part, by the ready availability and reasonable costs of comprehensive DNA and RNA sequencing assays. However, precision medicine is complex and incorporates entirely new types of data and treatment paradigms that are outside of the training of most oncologists in practice today.

Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, intended for clinicians, particularly those working in oncology. It provides an accessible introduction to the technological advances in DNA and RNA sequencing, gives a detailed overview of approaches to the interpretation of molecular test results and their point-of-care implementation for individual patients, and describes innovative clinical trial designs in oncology as well as characteristics of the computational infrastructures through which massive quantities of data are collected, stored, and used in precision medicine oncology.
 
Preface: Introduction to Precision Medicine Oncology ix
Lorna Rodriguez-Rodriguez
Kim M. Hirshfield
Shridar Ganesan
Contributors xv
1 Genomic Technology/Next-Generation Sequencing
1(35)
Hossein Khiabanian
Shridar Ganesan
Kim M. Hirshfield
Gregory Riedlinger
2 The Precision Medicine Oncology Molecular Tumor Board: Interpreting and Applying Precision Medicine to Patient Care
36(24)
Shridar Ganesan
Kim M. Hirshfield
Gregory Riedlinger
Lorna Rodriguez-Rodriguez
3 Clinical Research in Precision Medicine Oncology
60(21)
Kim M. Hirshfield
Shridar Ganesan
4 Infrastructures in Precision Medicine Oncology: Biobanks, Biomedical Informatics, and Big Data
81(12)
Shridar Ganesan
Kim M. Hirshfield
5 Future Directions in Precision Medicine Oncology
93(6)
Shridar Ganesan
Kim M. Hirshfield
Lorna Rodriguez-Rodriguez
Acknowledgments 99(2)
Index 101
Lorna Rodriguez-Rodriguez, editor, is Director of Precision Medicine at the Rutgers Cancer Institute of New Jersey and Professor of Obstetrics/Gynecology at Rutgers-RWJMS. She received her M.D. from the University of Puerto Rico, her Ph.D. from the University of Rochester, and her specialty in gynecologic cancers from the University of Michigan.