Scientists in obstetrics, gynecology, and other fields relating to reproduction report on recent developments in performing genetic analysis of human preimplantation embryos to predict the success of the implantation. They provide background on such topics as the genetic basis of inherited disease, genetic counselling, and gametogenesis and preimplantation embryo development. Then they discuss specific procedures, among then embryo biopsy, the diagnosis of single gene disorders, fluorescence in-situ hybridization and embryo sexing to avoid x-linked diseases, and chromosome abnormalities. Finally they look to the future of ethics, regulation, and the approach as a whole. Eight pages of color plates are included. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Preimplantation Genetic Diagnosis (PGD) is the detection and screening of genetic abnormality in gametes prior to fertilisation and embryos fertilised in vitro prior to implantation. This exciting new text provides an introduction and overview of the principles of PGD.
An exciting fusion of prenatal diagnosis (PD) with in vitro fertilisation (IVF), this book is will appeal to both the prenatal diagnosis community, of clinical geneticists and foetal medicine specialists within obstetrics and gynaecology, and the IVF community within reproductive medicine. It is also an essential introduction to PD, clinical genetics and IVF for non-specialists.
- A concise introduction to the field of PGD
- Detailed explanations of the techniques and procedures used
- The law and ethical implications of PGD
- Future uses of PGD
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