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E-raamat: Preparative Layer Chromatography

Edited by (Lafayette College, Easton, Pennsylvania, USA), Edited by (Wroclaw University of Technology, Poland)
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Kowalska (chromatography, University of Silesia, Poland) and Sherma (chemistry, emeritus, Lafayette College) offer a broad review of preparative layer chromatography (PLC) applications and working procedures for microseparations involving organic, inorganic, and organometallic compounds. The book contains theoretical background, chemical principles, and material on a range of applications, particularly the study of pharmaceuticals and biochemistry. Techniques and procedures are described in detail, and internationally available bulk sorbents and precoated chromatographic plates are evaluated. Rather than adopting a uniform style, contributors have been given the freedom present topics in whatever way they consider most effective. Although the book is designed for scientists with experience in the separation sciences, most chapters include introductory and background information, making the book appropriate for those with less experience. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)

Preparative Layer Chromatography explains how this method is used for separating large quantities of mixtures containing a wide variety of important compounds. It offers a broad review of preparative layer chromatography (PLC) applications and adaptable working procedures for microseparations involving organic, inorganic, and organometallic compounds. It describes current procedures and strategies for selecting the most suitable eluents and designing application-specific PLC systems. It also discusses all commercially available sorbents applicable to PLC including bulk sorbents and precoated chromatographic plates available on the international market.

Preparative Layer Chromatography explains how this method is used for separating large quantities of mixtures containing a wide variety of important compounds. It offers a broad review of preparative layer chromatography (PLC) applications and adaptable working procedures for microseparations involving organic, inorganic, and organometallic compounds.

The book contains theoretical background, chemical principles, and relevance of preparative layer chromatography (PLC) to a wide range of applications, particularly in the study of pharmaceuticals and biochemistry. Written by many of the best known and most knowledgeable specialists in the field, the chapters describe all the necessary techniques, current procedures, and superior strategies for selecting the most suitable eluents and designing application-specific PLC systems based on the data being sought. They provide comprehensive instructions, surrounding issues, and suggestions for optimizing optional working techniques within the framework of PLC. The book also provides a complete coverage of bulk sorbents and precoated chromatographic plates available on the international market.

A comprehensive, yet accessible source of information, Preparative Layer Chromatography is a relevant and practical text for experienced as well as novice researchers and practitioners involved in analytical, environmental, geochemical, biological, medicinal, and pharmaceutical analysis.

Arvustused

"...A valuable and important supplement to the existing vast chromatographic literature, [ this book] demonstrates the potential of planar chromatography for separation and isolation of pure compounds, even from very complex mixtures." -Journal of Liquid Chromatography, August 2006

"The contributor[ s']...experience integrated in the monograph forms a good basis for the readers." -Instrumentation Science & Technology, August 2006

"The [ first] eight chapters provide sound theoretical and methodological foundations of PLC. Numerous applications of PLC are reviewed in the second section, based on extensive literature. ...The application reviews provide numerous examples of solving experimental difficulties for the separation of complex mixtures." -Preparative Biochemistry & Biotechnology, August 2006

"The book is quite well produced and has a large number of illustrations . . . this volume is a worthy addition to the PLC literature, and a good place to start for the novice."

I.D. Wilson, in Chromatographia, January 2008, Vol. 67, No. 1/2




Teresa Kowalska, Joseph Sherma