Acknowledgments |
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v | |
About the IFST Advances in Food Science Book Series |
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xvii | |
List of Contributors |
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xix | |
Preface |
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xxiii | |
Section I Composition And Extraction Technologies For Algal Bioactives |
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1 Algae: A Functional Food with a Rich History and Future Superfood |
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3 | (11) |
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3 | (1) |
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1.2 History of Macro- and Microalgae Consumption |
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4 | (2) |
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1.3 Economic Relevance of Macro- and Microalgae |
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6 | (1) |
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7 | (1) |
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7 | (4) |
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11 | (3) |
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2 Influence of Seasonal Variation on Chemical Composition and Nutritional Profiles of Macro- and Microalgae |
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14 | (58) |
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14 | (8) |
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2.2 Influence of Seasonal Variation on Biochemical Composition of Micro- and Macroalgae |
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22 | (2) |
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24 | (7) |
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2.4 Carbohydrates/Polysaccharides |
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31 | (5) |
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36 | (2) |
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38 | (10) |
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2.6.1 Mycosporine-Like Amino Acids (MAAs) |
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46 | (1) |
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2.6.2 Phycobiliproteins and Lectins |
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47 | (1) |
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48 | (4) |
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2.8 Inorganic Elements and Minerals |
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52 | (4) |
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56 | (1) |
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57 | (2) |
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59 | (1) |
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59 | (1) |
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60 | (12) |
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3 Advances in Drying and Milling Technologies for Algae |
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72 | (24) |
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72 | (2) |
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3.2 Algal Cell Drying Technologies |
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74 | (7) |
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74 | (2) |
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76 | (1) |
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77 | (1) |
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77 | (1) |
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78 | (1) |
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78 | (1) |
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3.2.7 Heat Circulation Drying |
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79 | (1) |
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80 | (1) |
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3.2.9 Polypropylene Nonwoven Membrane Drying |
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80 | (1) |
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3.2.10 Refractance Window® Drying |
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81 | (1) |
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3.3 Algal Cell Milling Technologies |
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81 | (6) |
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3.3.1 Vortex-Bead Milling |
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81 | (2) |
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83 | (1) |
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3.3.3 High-Pressure Homogenization |
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84 | (2) |
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3.3.4 High-Speed Homogenization |
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86 | (1) |
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3.3.5 Liquid Nitrogen Grinding |
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86 | (1) |
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3.4 Challenges and Prospects |
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87 | (2) |
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3.4.1 Processing Technology |
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87 | (1) |
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87 | (1) |
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88 | (1) |
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3.4.4 Environmental Impacts |
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88 | (1) |
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89 | (1) |
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89 | (1) |
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89 | (7) |
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4 Recent Advances in the Use of Greener Extraction Technologies for the Recovery of Valuable Bioactive Compounds from Algae |
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96 | (27) |
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96 | (2) |
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4.2 Green Extraction Technologies and Applications |
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98 | (14) |
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4.2.1 Pulsed Electric Field (PEF) |
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98 | (3) |
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4.2.2 Supercritical Fluid Extraction (SFE) |
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101 | (5) |
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4.2.3 Pressurized Liquid Extraction (PLE) |
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106 | (2) |
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4.2.4 Microwave Assisted Extraction (MAE) |
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108 | (2) |
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4.2.5 Ultrasound Assisted Extraction (UAE) |
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110 | (2) |
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4.3 Combination Techniques |
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112 | (3) |
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4.4 Challenges and Future Perspectives |
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115 | (1) |
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116 | (1) |
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116 | (7) |
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5 Extraction Technologies for Functional Lipids |
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123 | (18) |
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123 | (1) |
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5.2 Conventional Extraction Techniques for Functional Lipids |
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124 | (3) |
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5.3 Application of Novel Extraction Technologies for Functional Lipids |
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127 | (7) |
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5.3.1 Algal Cell Disruption Methods |
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127 | (2) |
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5.3.2 Novel Extraction Methods |
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129 | (5) |
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5.4 Future Recommendations |
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134 | (1) |
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134 | (1) |
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135 | (6) |
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6 Extraction Technologies for Proteins and Peptides |
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141 | (22) |
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141 | (3) |
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6.2 Conventional Extraction Techniques for Proteins and Peptides |
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144 | (7) |
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6.2.1 Cell Disruption Methods |
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144 | (3) |
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6.2.2 Chemical Extraction |
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147 | (1) |
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6.2.3 Enzymatic Processes |
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148 | (1) |
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6.2.4 Recovery/Enrichment Techniques |
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149 | (1) |
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6.2.5 Protein Extraction Methods in Proteomics |
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150 | (1) |
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6.3 Emerging Technologies for Proteins and Peptides |
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151 | (3) |
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6.3.1 Microwave Assisted Extraction (MAE) |
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151 | (1) |
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6.3.2 Pulsed Arc Technology |
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151 | (2) |
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6.3.3 Pressurized Liquid Extraction (PLE) |
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153 | (1) |
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6.3.4 Sub- and Supercritical Fluid Extraction (SFE) |
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153 | (1) |
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6.3.5 High Hydrostatic Pressure (HHP) and Ultra-high Pressure Extraction (UHP) |
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154 | (1) |
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6.4 Conclusion and Future Outlook |
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154 | (1) |
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155 | (8) |
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7 Extraction Technologies to Recover Dietary Polyphenols from Macro- and Microalgae |
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163 | (25) |
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163 | (1) |
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7.2 Conventional Extraction Techniques for Polyphenols |
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164 | (2) |
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7.2.1 Liquid-Liquid Extraction (LLE) |
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165 | (1) |
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7.2.2 Solid-Liquid Extraction (SLE) |
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165 | (1) |
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7.3 Innovative Extraction Technologies for Isolation of Polyphenols from Macroalgae |
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166 | (12) |
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7.3.1 Enzyme-Assisted Extraction (EAE) |
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166 | (3) |
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7.3.2 Microwave Assisted Extraction (MAE) |
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169 | (1) |
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7.3.3 Pressurized Liquid Extraction (PLE) |
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170 | (1) |
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7.3.4 Subcritical Water Extraction (SWE) |
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171 | (3) |
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7.3.5 Supercritical Fluid Extraction (SFE) |
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174 | (2) |
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7.3.6 Ultrasound Assisted Extraction (UAE) |
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176 | (2) |
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7.4 Factors Affecting Extraction |
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178 | (2) |
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179 | (1) |
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180 | (1) |
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7.5 Challenges and Future Recommendations |
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180 | (1) |
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180 | (1) |
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181 | (7) |
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8 Extraction Technologies for Bioactive Polysaccharides |
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188 | (23) |
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188 | (1) |
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8.2 Polysaccharides in Seaweed |
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189 | (3) |
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8.3 Conventional Technologies for Polysaccharide Extraction |
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192 | (8) |
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8.4 Advanced Technologies for Polysaccharide Extraction |
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200 | (3) |
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8.4.1 Microwave Assisted Extraction (MAE) |
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200 | (1) |
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8.4.2 Ultrasound Assisted Extraction (UAE) |
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201 | (1) |
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8.4.3 Pressurized Liquid Extraction (PLE) |
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202 | (1) |
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8.4.4 Enzyme Assisted Extraction (EAE) |
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203 | (1) |
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203 | (1) |
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203 | (8) |
Section II Biological Properties Of Algal Derived Compounds |
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9 Potential Biological Activities Associated with Algal Derived Compounds |
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211 | (20) |
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211 | (2) |
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9.2 Antioxidant and Anticarcinogenic Activities of Macro- and Microalgal Constituents |
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213 | (11) |
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9.2.1 Mycosporine-like Amino Acids (MAAs) |
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214 | (4) |
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218 | (2) |
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220 | (1) |
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9.2.4 Carotenes and Xanthophylls |
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221 | (3) |
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9.3 Antiobesogenic Biological Activities of Macroalgal Constituents |
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224 | (1) |
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9.4 Antidiabetic Biological Activities of Macroalgal Constituents |
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224 | (2) |
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9.5 Prebiotic Biological Activities of Macroalgal Constituents |
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226 | (1) |
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9.6 Immune System Biological Activities of Macroalgal Constituents |
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227 | (1) |
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9.7 Conclusion and Future Work |
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227 | (1) |
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227 | (1) |
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228 | (3) |
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10 Algal Polysaccharides and Their Biological Properties |
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231 | (47) |
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231 | (1) |
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10.2 Structure of Marine Algae Polysaccharides |
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232 | (8) |
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234 | (1) |
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234 | (1) |
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235 | (1) |
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235 | (1) |
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236 | (1) |
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237 | (1) |
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238 | (1) |
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239 | (1) |
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239 | (1) |
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239 | (1) |
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10.3 Isolation and Purification of Polysaccharides from Algae |
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240 | (8) |
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241 | (5) |
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246 | (2) |
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10.4 Health-Promoting Activities of MAP |
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248 | (15) |
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10.4.1 Antioxidant Activity |
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249 | (4) |
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10.4.2 Immunomodulatory Activity |
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253 | (3) |
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10.4.3 Anticancer Activity |
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256 | (1) |
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10.4.4 Antiviral Activity |
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257 | (3) |
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10.4.5 Antihyperlipidemic Activity |
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260 | (1) |
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10.4.6 Anticoagulant Activity |
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261 | (1) |
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10.4.7 Antimicrobial Activity |
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262 | (1) |
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10.5 Conclusion and Future Trends |
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263 | (1) |
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264 | (14) |
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11 Marine Algal Derived Phenolic Compounds and their Biological Activities for Medicinal and Cosmetic Applications |
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278 | (57) |
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278 | (2) |
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11.2 Types and Structures of Phenolic Compounds from Algae |
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280 | (5) |
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11.2.1 Phenolic Compounds from Marine Cyanobacteria and Microalgae |
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281 | (1) |
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11.2.2 Phenolic Compounds from Green and Red Macroalgae |
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282 | (1) |
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11.2.3 Phenolic Compounds from Brown Macroalgae |
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283 | (1) |
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11.2.4 Variability of Phenolic Content in Space and Time |
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284 | (1) |
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11.3 Isolation and Purification of Phenolic Compounds from Algae |
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285 | (5) |
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11.3.1 Importance of the Pretreatment of the Biomass |
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285 | (1) |
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11.3.2 Extraction Procedures |
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286 | (3) |
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11.3.3 Quantification and Analyses of Phenolic Compounds |
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289 | (1) |
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11.4 Biological Properties of Phenolic Compounds in Health, Well-Being, and Cosmetics |
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290 | (16) |
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11.4.1 Antioxidant Properties |
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290 | (3) |
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11.4.2 Antiallergenic and Anti-inflammatory Properties |
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293 | (3) |
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11.4.3 Antidiabetic, Antiobesity Properties and Cardiovascular Protection |
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296 | (2) |
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11.4.4 Antiproliferative and Anticancer Properties |
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298 | (1) |
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11.4.5 Antimicrobial and Antiparasite Properties |
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299 | (2) |
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11.4.6 Antiviral Activities |
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301 | (1) |
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11.4.7 Mineralogenic and Osteogenic Activities |
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302 | (1) |
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11.4.8 Photoprotective Properties |
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303 | (1) |
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11.4.9 Biological Properties Specific to Cosmetics or Cosmeceuticals |
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304 | (2) |
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11.5 Potential Commercial Applications |
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306 | (2) |
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11.5.1 Interest in Health and Nutraceutical Ingredients |
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306 | (1) |
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11.5.2 Interest in Cosmetics and Cosmeceutical Ingredients |
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307 | (1) |
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11.6 Conclusions and Future Trends |
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308 | (2) |
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310 | (1) |
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310 | (25) |
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12 Algal Carotenoids: Recovery and their Potential in Disease Prevention |
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335 | (35) |
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335 | (2) |
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12.2 Types and Structure of Carotenoids in Microalgae |
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337 | (6) |
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12.2.1 General Occurrence |
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337 | (1) |
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12.2.2 Carotenoids Isolated from Seaweeds |
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337 | (6) |
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12.3 Isolation and Purification of Carotenoids from Algae |
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343 | (6) |
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343 | (1) |
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12.3.2 Microwave and Ultrasound Promoted Extraction |
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344 | (1) |
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345 | (1) |
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12.3.4 Adsorbent Assisted Carotenoid Extraction |
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346 | (1) |
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12.3.5 Ionic Liquid Mediated Carotenoid Extraction |
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347 | (1) |
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12.3.6 Surfactant Assisted Extraction Method |
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347 | (2) |
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12.4 Biological Properties of Carotenoids and Possible Health Effects |
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349 | (5) |
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349 | (1) |
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12.4.2 Antioxidant Activities |
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350 | (1) |
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12.4.3 Antidiabetic Activity |
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351 | (1) |
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352 | (1) |
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12.4.5 Antimicrobial Activities |
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352 | (1) |
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353 | (1) |
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12.4.7 Miscellaneous Biological Activities |
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353 | (1) |
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12.5 Potential Commercial Applications |
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354 | (4) |
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12.5.1 Microalgal Carotenoids in Commercial Applications |
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355 | (1) |
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12.5.2 Commercial Applications of Astaxanthin and Lutein |
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355 | (1) |
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12.5.3 Macroalgal Carotenoids in Commercial Applications |
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356 | (1) |
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12.5.4 Nutraceutical Supplements |
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357 | (1) |
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12.5.5 Commercial Application of Algal Carotenoids in Feed |
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357 | (1) |
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12.6 Conclusions and Future Recommendations |
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358 | (1) |
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358 | (1) |
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358 | (12) |
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13 Algal Derived Functional Lipids and their Role in Promoting Health |
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370 | (48) |
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370 | (1) |
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13.2 Types and Structures of Fatty Acids from Algae |
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371 | (7) |
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13.3 Isolation and Purification of FAs from Algae |
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378 | (6) |
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13.3.1 Isolation of FAs from Algae |
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378 | (1) |
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13.3.2 Purification of FAs from Algae |
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378 | (6) |
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13.4 Health Properties of FAs |
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384 | (12) |
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13.4.1 Lipids, FAs from Seaweeds and Cosmetic or Cosmeceutical Uses |
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384 | (3) |
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13.4.2 Preventive Effects of n-3 PUFAs on CVD and Metabolic Syndrome |
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387 | (3) |
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13.4.3 Contribution of n-3 PUFAs in Cancer Risk Factor Prevention and/or Therapy |
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390 | (6) |
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13.4.4 Antiviral Activities |
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396 | (1) |
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13.5 Potential Commercial Applications |
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396 | (1) |
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13.6 Conclusion and Future Trends |
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397 | (1) |
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398 | (1) |
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398 | (20) |
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14 Algal Proteins and Peptides: Current Trends and Future Prospects |
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418 | (28) |
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418 | (1) |
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14.2 Isolation and Purification of Proteins from Algae |
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419 | (2) |
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14.3 Structural Characteristics of Micro- and Macroalgae Peptides |
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421 | (3) |
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14.3.1 Structures of Peptides from Microalgae |
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421 | (2) |
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14.3.2 Structure of Protein and Peptides from Macroalgae |
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423 | (1) |
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14.4 Protein and Peptide Extraction Methods from Algae |
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424 | (7) |
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14.4.1 Physical Processes |
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424 | (3) |
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14.4.2 Enzymatic Hydrolysis |
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427 | (1) |
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14.4.3 Enzyme Assisted Extraction (EAE) |
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428 | (1) |
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14.4.4 Ultrasound Assisted Extraction |
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428 | (1) |
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14.4.5 Pulsed Electric Field |
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429 | (1) |
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14.4.6 Microwave Assisted Extraction |
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429 | (1) |
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14.4.7 Membrane Filtration |
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430 | (1) |
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14.4.8 High Hydrostatic Pressure (HHP) |
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430 | (1) |
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14.5 Biological Properties of Micro- and Macroalgal Peptides and Possible Health Effects |
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431 | (5) |
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14.5.1 Antihypertensive Peptides |
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431 | (1) |
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14.5.2 Anticancer Peptides and Proteins |
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431 | (1) |
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14.5.3 Antioxidant Micro- and Macroalgal Peptides |
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432 | (1) |
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14.5.4 Anti-Inflammatory Peptides |
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432 | (1) |
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14.5.5 Algal Proteins and Peptides on Immunomodulation |
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433 | (1) |
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14.5.6 Antiobesity Peptides |
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434 | (1) |
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14.5.7 Antidiabetic Proteins and Peptides |
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434 | (1) |
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14.5.8 Antimicrobial Algal Peptides |
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435 | (1) |
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14.5.9 Biological Value of Algal Proteins in Human Nutrition |
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435 | (1) |
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14.6 Potential Commercial Applications of Micro- and Macroalgal Peptides and Proteins |
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436 | (1) |
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14.6.1 Microalgae Peptides and Proteins in Commercial Applications |
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436 | (1) |
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14.6.2 Macroalgal Peptides and Proteins in Commercial Applications |
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437 | (1) |
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14.7 Conclusion and Future Recommendations |
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437 | (1) |
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438 | (1) |
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438 | (8) |
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15 Algal Dietary Fiber and its Health Benefits |
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446 | (21) |
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446 | (1) |
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447 | (5) |
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15.2.1 Algae as a Source of Dietary Fiber |
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449 | (2) |
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15.2.2 Marine Algal Polysaccharides |
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451 | (1) |
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15.3 Physical Properties of Dietary Fiber (Dispersibility, Viscosity, Binding Capacity, Fermentability) |
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452 | (4) |
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452 | (1) |
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453 | (1) |
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454 | (1) |
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455 | (1) |
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15.4 Therapeutic Effect of Algal Dietary Fibers |
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456 | (2) |
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15.4.1 Antihypertensive Effects |
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456 | (1) |
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15.4.2 Antiobesity Attributes |
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457 | (1) |
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457 | (1) |
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15.5 Potential Commercial Applications |
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458 | (1) |
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15.6 Conclusion and Future Recommendations |
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459 | (1) |
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460 | (7) |
Section III Application Of Algae And Algal Components |
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16 Applications of Algae and Algae Extracts in Human Food and Feed |
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467 | (20) |
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467 | (1) |
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16.2 Nutritional Composition of Algae |
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468 | (1) |
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16.3 Application of Whole Algae in Food Products |
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468 | (5) |
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16.3.1 Muscle-Based Foods |
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468 | (1) |
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469 | (2) |
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16.3.3 Cereal-Based Food Products |
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471 | (2) |
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473 | (1) |
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16.4 Application of Whole Algae in Feed |
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473 | (2) |
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16.5 Algal Extracts as Ingredients in Food Products |
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475 | (6) |
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475 | (2) |
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477 | (1) |
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478 | (1) |
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479 | (1) |
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16.5.5 Phenolic Compounds |
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480 | (1) |
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16.6 Conclusion and Future Recommendations |
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481 | (1) |
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481 | (6) |
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17 Role of Algal Compounds for Human Health |
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487 | (19) |
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487 | (1) |
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17.2 Classification of Algae |
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488 | (2) |
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488 | (1) |
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489 | (1) |
|
|
489 | (1) |
|
17.2.4 Chlorophyta (Green Algae) |
|
|
489 | (1) |
|
17.2.5 Rhodophyta (Red Algae) |
|
|
490 | (1) |
|
17.2.6 Phaeophyta (Brown Algae) |
|
|
490 | (1) |
|
|
490 | (1) |
|
17.3 Proximate Composition of Algae |
|
|
490 | (10) |
|
17.3.1 Algal Carbohydrates |
|
|
490 | (4) |
|
17.3.2 Proteinaceous Biomolecules in Algae |
|
|
494 | (2) |
|
|
496 | (3) |
|
|
499 | (1) |
|
|
500 | (1) |
|
17.4 Commercial Importance of Macroalgae in Human Nutrition |
|
|
500 | (2) |
|
|
502 | (4) |
|
18 Advancements in Algae in Nutraceutical and Functional Food |
|
|
506 | (31) |
|
|
|
|
506 | (1) |
|
18.2 Algal Derived Molecules |
|
|
507 | (17) |
|
|
507 | (4) |
|
|
511 | (2) |
|
|
513 | (4) |
|
|
517 | (7) |
|
|
524 | (2) |
|
|
526 | (11) |
|
19 Role of Algal Derived Compounds in Pharmaceuticals and Cosmetics |
|
|
537 | (67) |
|
|
|
|
|
537 | (1) |
|
19.2 Algae as a Source of Active Ingredients for Pharmaceutical Products |
|
|
538 | (21) |
|
19.2.1 Sulfated Polysaccharides and Other Phycocolloids |
|
|
539 | (10) |
|
19.2.2 Phlorotannins and Other Polyphenols |
|
|
549 | (3) |
|
|
552 | (2) |
|
19.2.4 PUFAs and Other Lipidic Compounds |
|
|
554 | (2) |
|
19.2.5 Carotenoids and Other Pigments |
|
|
556 | (1) |
|
19.2.6 Peptides and Proteins |
|
|
557 | (1) |
|
19.2.7 Other Bioactive Compounds |
|
|
558 | (1) |
|
19.3 Potential Pharmaceutical Formulations from Algae |
|
|
559 | (8) |
|
19.3.1 Potential Anticancer, Cytotoxic, and Antiproliferative Pharmaceutical Formulations |
|
|
559 | (2) |
|
19.3.2 Potential Antithrombotic, Anticoagulant, and Antihypertensive Pharmaceutical Formulations |
|
|
561 | (1) |
|
19.3.3 Potential Antilipidemic and Anticholesterolemic Pharmaceutical Formulations |
|
|
562 | (1) |
|
19.3.4 Potential Antiobesity and Antidiabetic Pharmaceuticals Formulations |
|
|
562 | (2) |
|
19.3.5 Potential Antibacterial, Antiviral, and Antifungal Pharmaceutical Formulations |
|
|
564 | (1) |
|
19.3.6 Potential Immunomodulatory Anti-Inflammatory Pharmaceutical Formulations |
|
|
565 | (1) |
|
19.3.7 Potential Neuroprotective Pharmaceutical Formulations for Healthy Nervous System |
|
|
565 | (1) |
|
19.3.8 Other Potential Pharmacological Formulations from Algae |
|
|
566 | (1) |
|
19.4 Algae as a Source of Active Ingredients for Cosmeceuticals |
|
|
567 | (13) |
|
|
568 | (7) |
|
19.4.2 Phenols and Polyphenols |
|
|
575 | (1) |
|
|
576 | (1) |
|
|
576 | (1) |
|
19.4.5 PUFAs and Other Lipid Compounds |
|
|
577 | (1) |
|
19.4.6 Proteins and Amino Acids |
|
|
577 | (1) |
|
|
578 | (1) |
|
|
579 | (1) |
|
19.5 Potential Cosmeceutical Formulations from Algae |
|
|
580 | (3) |
|
19.5.1 Moisturizing Cosmeceutical Formulations |
|
|
581 | (1) |
|
19.5.2 Antiaging and Photoageing Cosmeceutical Formulations |
|
|
581 | (1) |
|
19.5.3 Skin Whitening Cosmeceutical Formulations |
|
|
582 | (1) |
|
19.5.4 Other Potential Cosmeceutical Formulations |
|
|
582 | (1) |
|
19.6 Conclusion and Future Trends |
|
|
583 | (1) |
|
|
584 | (20) |
|
20 Economic Status of Seaweed: Production, Consumption, Commercial Applications, Hazards, and Legislations |
|
|
604 | (13) |
|
|
|
|
|
604 | (1) |
|
20.2 World Seaweed Utilization |
|
|
605 | (6) |
|
20.2.1 World Seaweed Production |
|
|
605 | (1) |
|
20.2.2 Trends in Seaweed Production and Consumption |
|
|
605 | (5) |
|
20.2.3 Economic Relevance of Seaweed |
|
|
610 | (1) |
|
20.3 Commercial Usage of Seaweed and Seaweed Functional Components |
|
|
611 | (1) |
|
20.3.1 Food Applications of Seaweed |
|
|
611 | (1) |
|
20.3.2 Nonfood Applications of Seaweed |
|
|
612 | (1) |
|
20.4 Hazards Associated with Seaweed Applications |
|
|
612 | (1) |
|
|
613 | (1) |
|
|
614 | (1) |
|
|
614 | (3) |
Index |
|
617 | |