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E-raamat: Single-Cell Assays: Microfluidics, Genomics, and Drug Discovery

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  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2689
  • Ilmumisaeg: 10-Jul-2023
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071633236
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Single-Cell Assays: Microfluidics, Genomics, and Drug DiscoverySuurem pilt
  • Formaat: EPUB+DRM
  • Sari: Methods in Molecular Biology 2689
  • Ilmumisaeg: 10-Jul-2023
  • Kirjastus: Springer-Verlag New York Inc.
  • Keel: eng
  • ISBN-13: 9781071633236
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This detailed volume explores the use of single-cell assays in research for drug discovery, microfluidics, and more. The book delves into methodologies involving a variety of cell types and diseases, small molecules and biologics, as well as studies of the genome and transciptome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Single-Cell Assays: Microfluidics, Genomics, and Drug Discovery serves to enable researchers to obtain a rapid overview in state-of-the-art microfluidic single-cell assays and an impression of what possibilities these assays offer to drug discovery.
Detection of Single Non-Small Cell Lung Cancer Cell Multi-Drug
Resistance with Single Cell Bioanalyzer.- Cytosolic Calcium Measurement
Utilizing a Single Cell Biochip to Study the Effect of Curcumin and
Resveratrol on a Single Glioma Cell.- Dielectrophoresis-Assisted
Self-Digitization Chip for High-Efficiency Single-Cell Analysis.- Optical pH
Monitoring in Microdroplet Platforms for Live Cell Experiments Using
Colloidal Surfactants.- PicoShells: Hollow Hydrogel Microparticles for
High-Throughput Screening of Clonal Libraries.- Single Cell Micropatterning
by Non-Fouling Hydrogels.- Microfluidics-Enabled Isolation and Single-Cell
Analysis of Circulating Tumor Cells.- Discrimination of Multidrug Resistance
in Cancer Cells Achieved Using Single-Cell Analysis.- Microfluidic Approach
for Modelling Coupled Circadian Clock.- A High-Throughput Single-Cell Assay
on a Valve-Based Microfluidic Platform Applied to Protein Quantification,
Immune Response Monitoring, and Drug Discovery.- Single-Cell Exogenous Gene
Transfection Analysis Chip.- Double Emulsion Flow Cytometry for Rapid Single
Genome Detection.- Single-Cell Analysis of circRNA Using ddPCR.- A SINC-Seq
Protocol for the Analysis of Subcellular Gene Expression in Single Cells.-
Profiling Single-Cell Genome and Transcriptome by scONE-Seq.- Single
Extracellular Vesicle Analysis Using Droplet Microfluidics.
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