Muutke küpsiste eelistusi

E-raamat: Studies on Arthritis and Joint Disorders

  • Formaat - PDF+DRM
  • Hind: 172,28 €*
  • * hind on lõplik, st. muud allahindlused enam ei rakendu
  • Lisa ostukorvi
  • Lisa soovinimekirja
  • See e-raamat on mõeldud ainult isiklikuks kasutamiseks. E-raamatuid ei saa tagastada.

DRM piirangud

  • Kopeerimine (copy/paste):

    ei ole lubatud

  • Printimine:

    ei ole lubatud

  • Kasutamine:

    Digitaalõiguste kaitse (DRM)
    Kirjastus on väljastanud selle e-raamatu krüpteeritud kujul, mis tähendab, et selle lugemiseks peate installeerima spetsiaalse tarkvara. Samuti peate looma endale  Adobe ID Rohkem infot siin. E-raamatut saab lugeda 1 kasutaja ning alla laadida kuni 6'de seadmesse (kõik autoriseeritud sama Adobe ID-ga).

    Vajalik tarkvara
    Mobiilsetes seadmetes (telefon või tahvelarvuti) lugemiseks peate installeerima selle tasuta rakenduse: PocketBook Reader (iOS / Android)

    PC või Mac seadmes lugemiseks peate installima Adobe Digital Editionsi (Seeon tasuta rakendus spetsiaalselt e-raamatute lugemiseks. Seda ei tohi segamini ajada Adober Reader'iga, mis tõenäoliselt on juba teie arvutisse installeeritud )

    Seda e-raamatut ei saa lugeda Amazon Kindle's. 

This book reviews scientific and clinical knowledge of the role of free radicals and antioxidants in the pathology of arthritis and other joint diseases. Bench-to-bedside coverage of diagnostic tools, lab methods, biomarkers as therapeutic agents and more.

This next volume in our established series proposes to systematically review the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as “oxidative stress”, in the pathology of arthritis and other joint diseases. It will describe the most current diagnostic tools , laboratory methods and technology, to suggest ways of prevention and treatment and to emphasize the concept of the bench-to-bedside approach. The book will also provide specific coverage on emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents and several more relevant aspects. In addition, the book will promote the concept of using biomarkers representative of oxidative stress reactions and free radical damage , as well as describe the effect of antioxidants in treating disease in clinical trials. The content will be valuable to researchers studying the development of arthritis/joint disease, and clinicians treating patients with these diagnoses.

Arvustused

From the reviews:

This is a thorough overview of the role of oxidative damage in joint and connective tissue disease. This is a highly specialized area that is important for rheumatologists as well as for basic scientists to understand. book is appropriate for all practitioners and academicians who are interested in the role of oxidative damage in joint disorders. The authors do a great job of connecting basic science concepts with clinical disease. easy to read, and diagrams and charts are clear and used appropriately. (Jonathan Miner, Doodys Book Reviews, July, 2013)

Part I Biology of Oxidative Stress in Joint Disorders
1 Soluble Proteomic Biomakers in the Management of Arthritis
3(30)
Yves Henrotin
Ali Mobasheri
2 Regulation of T-Cell Functions by Oxidative Stress
33(16)
Stuart J. Bennett
Helen R. Griffiths
3 Nitric Oxide and the Respiratory Chain in Synovial Cells and Chondrocytes
49(18)
Maria J. Lopez-Armada
Marta N. Valcarcel-Ares
Romina R. Riveiro-Naveira
Carlos Vaamonde-Garcia
4 Adipokines, Molecular Players at the Crossroad Between Inflammation and Oxidative Stress: Role in Arthropathies
67(22)
Morena Scotece
Javier Conde
Rodolfo Gomez
Veronica Lopez
Francisca Lago
Juan J. Gomez-Reino
Oreste Gualillo
5 Regulation of Cartilage and Bone Metabolism by Oxidative Stress
89(20)
Anja Niehoff
Christoph Ziskoven
6 Role of Oxidative Stress in Bone Ageing
109(18)
Sergio Portal-Nunez
Pedro Esbrit
Part II Clinical Aspects of Oxidative Stress in Joint Disorders
7 Genetic Component of Oxidative Stress in Rheumatoid Arthritis
127(18)
F. David Carmona
Jose-Ezequiel Martin
Javier Martin
8 Oxidative Stress in Rheumatoid Arthritis
145(24)
Katalin E. Szabo-Taylor
Gyorgy Nagy
Paul Eggleton
Paul G. Winyard
9 Oxidative Stress and Premature Atherosclerosis in Rheumatoid Arthritis
169(14)
Fredeswinda I. Romero-Bueno
10 Role of Oxidative Stress and Reactive Oxygen Radicals in the Pathogenesis of Systemic Sclerosis
183(16)
Sonsoles Piera-Velazquez
Sergio A. Jimenez
11 Antioxidant and Antiinflammatory Properties of Heme Oxygenase-1 in Osteoarthritic Articular Cells
199(24)
Maria Isabel Guillen
Isabel Garcia-Arnandis
Victoria Clerigues
Javier Megias
Maria Jose Alcaraz
12 Oxidative Stress at the Crossroads Between Osteoarthritis and Metabolic Syndrome
223(14)
James D. Katz
Manuel T. Velasquez
13 Metabolic Syndrome and Gout
237(14)
Eswar Krishnan
Part III Antioxidative Approach in Joint Disorders
14 Natural Antioxidants in the Pharmacological Treatment of Rheumatic Immune and Inflammatory Diseases
251(24)
Rosaria Meli
Giuseppina Mattace Raso
15 Antioxidants in the Treatment of Osteoarthritis and Bone Mineral Loss
275(22)
Ali Mobasheri
Mehdi Shakibaei
Hans Konrad Biesalski
Yves Henrotin
16 Anti-cytokine Agents to Combat Oxidative Stress
297(14)
Makoto Hirao
Jun Hashimoto
Norihiro Nishimoto
17 Oxidative Conditioning and Treatment for Osteoarthritis
311(22)
Prem S. Ramakrishnan
Marc J. Brouillette
James A. Martin
18 The Role of Sirtuins in Arthritis
333(16)
Diego Kyburz
Fabienne Niederer
19 MicroRNA Molecules, Master Regulators, Biomarkers, and Potential Therapies
349(20)
Olga Sanchez-Pernaute
Maria Perez-Ferro
20 Estrogen-Dependent Transcriptional Activity: A Protection Against ROS in Osteoarthritis
369(24)
Laura Lugo
Gabriel Herrero-Beaumont
Editors' Biographies 393(2)
Index 395
María José Alcaraz, Ph.D., is a full Professor in Pharmacology  at the Department of Pharmacology, University of Valencia, Spain, and former Head of this Department. After completing her Ph.D. at the University of Valencia with Extraordinary Award, she undertook postdoctoral research funded by the Spanish Ministery of Education at the Department of Pharmacology, King's Col. London (1983-1984).  She also worked as a visiting researcher at the Unité 348 INSERM, Paris (1998) and received  the Dr. Esteve Foundation Award to the best publication in pharmacology and Almirall Award to the best project in pharmacology.  In addition to act as editor or referee for several international journals and expert for scientific projects evaluation in different countries and international organizations,  she has played an active role in international cooperation with Latin America. Maria José Alcaraz is the head of the Pharmacology of Inflammation group, Department of Pharmacology, University of Valencia, Spain, which focuses on the pathogenesis of the inflammatory process, oxidative stress regulation and the development of new therapeutic targets for the treatment of joint diseases mainly rheumatoid arthritis and osteoarthritis.  













Dr. Oreste Gualillo obtained his PhD in Pharmacology at the Department of Experimental Pharmacology of the University Federico II, Naples (Italy). He received training in molecular endocrinology under Prof. Paul A. Kelly at the Necker School of Medicine, Paris. In 1998 he moved to the Laboratory of Molecular Endocrinology of the University of Santiago de Compostela, Spain, where he worked as a Marie Curie postdoctoral research fellow. In 2001 he set up his own research group at the Santiago University Clinical Hospital. He is currently a Class A Stable researcher with the SERGAS (Servizo Galegode Saude) and Carlos III Health Institute of the Spanish Ministry of Health, heading the NEIRID (NeuroEndocrine Interactions in Rheumatologyand Inflammatory Diseases) research laboratory of the Santiago University Clinical Hospital at the IDIS (Instituto de Investigación Sanitaria) of Santiago de Compostela. He has published over 80 papers and in the last years his research was focussed on defining the multifaceted role of adipokines in chondrocyte pathophysiology.

 

Olga Sánchez-Pernaute, MD, PhD, is a senior rheumatologist in the Jimenez Diaz Foundation University Hospital and assistant Prof at the Autonoma University School of Medicine in Madrid. She has a dilated background in translational research, focused on the study of innate mechanisms of disease associated to autoimmune rheumatic conditions. Of note are her early contributions to the field of inflammatory mediators in experimental models of arthritis, and the pioneer work on the role of fibrin in the progression of synovitis. She was invited for a one-year fellowship at the Laboratory of Experimental Rheumatology of Zürich University, where she developed her research interest in epigenetics. In the last few years she has created a Multidisciplinary Unit for Systemic Autoimmune Diseases that she currently directs at her Institution.